A5082672076- Cardiac Health and Mental Health
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Heart Rate Variability and Autonomic Control
- Colorectal Cancer Screening and Detection
- Cardiovascular Health and Risk Factors
- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Mental Health Treatment and Access
- Cardiovascular and exercise physiology
- Cardiac pacing and defibrillation studies
- Health disparities and outcomes
- Parathyroid Disorders and Treatments
- Cardiovascular Disease and Adiposity
- Mobile Health and mHealth Applications
- Chronic Kidney Disease and Diabetes
- Pancreatic and Hepatic Oncology Research
- Stroke Rehabilitation and Recovery
- Cardiovascular Health and Disease Prevention
- Stress Responses and Cortisol
- Cardiac Valve Diseases and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Atrial Fibrillation Management and Outcomes
- Telemedicine and Telehealth Implementation
University of California, San Francisco
2015-2024
San Francisco VA Medical Center
2015-2024
Quality Enhancement Research Initiative
2017-2024
San Francisco VA Health Care System
2015-2024
Lee University
2023
Collaborative Group (United States)
2021
United States Department of Veterans Affairs
1998-2021
University of California System
2006-2020
Veterans Health Administration
2009-2020
University of Pennsylvania
2020
<h3>Context</h3>Depressive symptoms predict adverse cardiovascular outcomes in patients with coronary heart disease, but the mechanisms responsible for this association are unknown.<h3>Objective</h3>To determine why depressive associated an increased risk of events.<h3>Design and Participants</h3>The Heart Soul Study is a prospective cohort study 1017 outpatients stable disease followed up mean (SD) 4.8 (1.4) years.<h3>Setting</h3>Participants were recruited between September 11, 2000,...
Little is known regarding the extent to which patient-reported health status, including symptom burden, physical limitation, and quality of life, determined by psychosocial vs physiological factors among patients with chronic disease.To compare contributions depressive symptoms measures cardiac function status coronary artery disease.Cross-sectional study 1024 adults stable disease recruited from outpatient clinics in San Francisco Bay Area between September 2000 December 2002. Main Measures...
OBJECTIVES: To determine whether current use of central nervous system (CNS)‐active medications, including benzodiazepines, antidepressants, anticonvulsants, and narcotics, increases the risk for subsequent falls. DESIGN: Prospective cohort study. SETTING: Four clinical centers in Baltimore, Maryland; Portland, Oregon; Minneapolis, Minnesota; Monongahela Valley, Pennsylvania. PARTICIPANTS: Eight thousand one hundred twenty‐seven women aged 65 older participating fourth examination Study...
Researchers increasingly use meta-analysis to synthesize the results of several studies in order estimate a common effect. When outcome variable is continuous, standard meta-analytic approaches assume that primary report sample mean and deviation outcome. However, when skewed, authors sometimes summarize data by reporting median one or both (i) minimum maximum values (ii) first third quartiles, but do not deviation. To include these meta-analysis, methods have been developed from reported...
<h3>Background</h3> Depression leads to adverse outcomes in patients with coronary heart disease (CHD). Medication nonadherence is a potential mechanism for the increased risk of CHD events associated depression, but it not known whether depression medication outpatients stable CHD. <h3>Methods</h3> We examined association between current major (assessed using Diagnostic Interview Schedule) and self-reported adherence cross-sectional study 940 <h3>Results</h3> A total 204 participants (22%)...
A longstanding but controversial hypothesis is that individuals who exhibit frequent, large increases in blood pressure (BP) during psychological stress are at risk for developing essential hypertension. We tested whether BP changes predict incident hypertension young adults.We used survival analysis to hypertensive status 13 years of follow-up a sample >4100 normotensive black and white men women (age entry, 18 30 years) enrolled the CARDIA study. responses 3 challenges--cold pressor, star...
Background: Despite cardiac rehabilitation (CR) being shown to improve health outcomes among patients with heart disease, its use has been suboptimal. In response, the Million Hearts Cardiac Rehabilitation Collaborative developed a road map CR use, including increasing participation rates ≥70% by 2022. This observational study provides current estimates measure progress and identifies populations regions most at risk for service underutilization. Methods Results: We identified Medicare...
<h3>Background</h3> Previous studies have suggested that depression is associated with falls and low bone density, but it not known whether leads to an increased risk of fracture. <h3>Subjects Methods</h3> We conducted a prospective cohort study in elderly white women who were recruited from population-based listings the United States. At second visit (1988-1990), 7414 participants completed 15-item Geriatric Depression Scale considered depressed if they reported 6 or more symptoms...
Background— Serum creatinine and related estimating equations predict cardiovascular events mortality among persons with coronary heart disease (CHD). Cystatin C is a novel sensitive endogenous marker of kidney function. Whether cystatin concentrations are associated adverse ambulatory CHD unknown. Methods Results— Nine hundred ninety were categorized into quartiles serum at inception, ≤0.91 mg/L constituting the lowest quartile (I) ≥1.30 highest (IV). Cox proportional hazards models...
ContextPostmenopausal hormone therapy is commonly used by women for disease prevention, but its effects on quality of life have not been well documented.ObjectiveTo determine the effect estrogen plus progestin as secondary prevention in with coronary artery disease.Design, Setting, and ParticipantsA total 2763 postmenopausal documented (mean age, 67 years) Heart Estrogen/Progestin Replacement Study, a randomized, placebo-controlled, double-blind trial conducted from January 1993 to July 1998...
Fetuin-A is a multifunctional hepatic secretory protein that inhibits the action of insulin in experimental animals. We evaluated association between human serum fetuin-A and metabolic syndrome (MetS) cohort persons with coronary artery disease.We defined MetS by National Cholesterol Education Program criteria among 711 nondiabetic outpatients disease. The mean age was 67 years, 82% were male. divided participants into quartiles concentrations. A total 45% (80 177) highest quartile had...
Identification of individuals at high risk for cardiovascular events is important the optimal use primary and secondary prevention measures.To determine whether plasma levels amino terminal fragment prohormone brain-type natriuretic peptide (NT-proBNP) predict or death independent other available prognostic tests.Prospective cohort study (2000-2002) 987 in California with stable coronary heart disease Heart Soul Study, who were followed up a mean 3.7 (range, 0.1-5.3) years.The association...
<h3>Background</h3> Major depression is associated with increased mortality, but it not known whether patients who report depressive symptoms have greater mortality. <h3>Subjects and Methods</h3> We performed a prospective cohort study of 7518 white women 67 years age or older were recruited from population-based listings in Baltimore, Md, Minneapolis, Minn, Portland, Ore, the Monongahela Valley, Pa. Participants completed Geriatric Depression Scale (short form) considered depressed if they...
<h3>Background</h3> Use of central nervous system (CNS) active medications may increase the risk for fractures. Prior studies are limited by incomplete control confounders. <h3>Methods</h3> To determine whether use CNS medications, including benzodiazepines, antidepressants, anticonvulsants, and narcotics, increases fracture in elderly, community-dwelling women, we examined these 4 categories a cohort 8127 older women followed participants prospectively incident nonspine fractures, hip...
Major depressive disorder is a risk factor for the development of incident coronary heart disease events in healthy patients and adverse cardiovascular outcomes with established disease. Depression present 1 5 outpatients 3 congestive failure, yet majority cases are not recognized or appropriately treated. It known whether treating depression improves outcomes, but antidepressant treatment selective serotonin reuptake inhibitors generally safe, alleviates depression, quality life. This...