A5020626829- Renal Transplantation Outcomes and Treatments
- Cytomegalovirus and herpesvirus research
- Neurological Complications and Syndromes
- Organ Transplantation Techniques and Outcomes
- Cutaneous lymphoproliferative disorders research
- Cutaneous Melanoma Detection and Management
- Pharmacological Effects and Toxicity Studies
- Xenotransplantation and immune response
- Medication Adherence and Compliance
- Transplantation: Methods and Outcomes
- Nonmelanoma Skin Cancer Studies
- Polyomavirus and related diseases
- Parvovirus B19 Infection Studies
Hospital do Rim e Hipertensão
2016-2023
Universidade Federal de São Paulo
2016-2018
Institute of Nephro Urology
2017
Pediatric Nephrology of Alabama
2016
In Brief Background De novo use of mammalian target rapamycin inhibitors after kidney transplantation is associated with a concentration-dependent incidence wound healing adverse events (WHAE). The objective this analysis was to compare the WHAE in patients receiving everolimus (EVR) or mycophenolate sodium (MPS). Methods This predefined subanalysis single-center prospective randomized study which 288 transplant recipients tacrolimus and prednisone were for 3 different regimens: rabbit...
Although mammalian target of rapamycin inhibitors (mTORi) are associated with a lower incidence the first episode cytomegalovirus (CMV) infection/disease in kidney transplant recipients receiving calcineurin (CNIs), efficacy and safety conversion from antimetabolite to an mTORi for prevention CMV recurrence unknown.In this single-center prospective randomized trial, low-immunological-risk, CMV-positive preemptive therapy were be converted (sirolimus [SRL]) or not (control [CTR]) immediately...
Cytomegalovirus (CMV) infection in kidney transplantation has changed its clinical spectrum, mostly due to the current and more effective immunosuppression. In absence of preventive strategies it is associated with significant morbi-mortality. Objective: This study evaluated incidence CMV events effect on outcomes recipients without pharmacological prophylaxis or targeted preemptive treatment. Results: The cohort comprised 802 transplants between 04/30/2014 04/30/2015. majority received...
<b><i>Background:</i></b> This analysis compared efficacy, renal function, and histology in kidney transplant recipients receiving tacrolimus (TAC) combined with everolimus (EVR) or mycophenolate (MPS). <b><i>Methods:</i></b> was a retrospective from randomized trial who received single 3 mg/kg dose of rabbit antithymocyte globulin (r-ATG), TAC, EVR, prednisone (PRED; r-ATG/EVR, <i>n</i> = 85), basiliximab (BAS), PRED (BAS/EVR, 102)...
Abstract Background The use of m TOR inhibitors is associated with lower incidence CMV infections but its effect on viral load has not been investigated. Aims, Materials and Methods This post‐hoc analysis included data from 273 seropositive kidney transplant recipients randomized to receive anti‐thymocyte globulin everolimus ( rAGT / TAC EVR , n = 81), basiliximab BAS 97) or mycophenolate MPS 95). All patients received tacrolimus ) corticosteroids. Preemptive therapy based weekly pp65...
Renal transplant recipients are submitted to immunosuppression avoid graft rejection, which makes them susceptible various conditions. Furthermore, these individuals present malignant tumors more frequently than the general population, including nonmelanoma skin cancer. The individual genetic basis that acts in pathogenesis of cutaneous cancer may a protection or susceptibility factor for disease development. One factors is HLA complex.