A5061248903- Renal Transplantation Outcomes and Treatments
- Renal Diseases and Glomerulopathies
- Neurological Complications and Syndromes
- Cytomegalovirus and herpesvirus research
- Polyomavirus and related diseases
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Complement system in diseases
- Vasculitis and related conditions
- Esophageal and GI Pathology
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Transplantation: Methods and Outcomes
- Chronic Kidney Disease and Diabetes
- Blood groups and transfusion
- Blood disorders and treatments
- Renal and Vascular Pathologies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Immunodeficiency and Autoimmune Disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Pharmacological Effects and Toxicity Studies
- Drug-Induced Adverse Reactions
- Retinal Imaging and Analysis
- Antifungal resistance and susceptibility
- AI in cancer detection
- Mycobacterium research and diagnosis
Hospital do Rim e Hipertensão
2017-2024
Universidade Federal da Bahia
2023
Universidade Estadual de Feira de Santana
2023
Universidade de Brasília
2023
Yahoo (United Kingdom)
2023
Universidade Federal de São Paulo
2017-2021
Introduction Thrombotic microangiopathy (TMA) in post-transplant setting has heterogeneous clinical manifestations. Methods We retrospectively studied data of 89 patients with TMA, which was characterized by thrombi at least one glomerulus and/or arteriole. Systemic TMA defined thrombocytopenia and microangiopathic anemia early onset when occurred less than 90 days post transplant. Results The cumulative incidence 0.93%. majority the recipients were young (mean age 39 years), female (52%)...
Abstract Early hospital readmission (EHR) is associated with increased mortality after kidney transplantation. This influenced by population demographics and the comprehensiveness of healthcare system. We investigated incidence risk factors EHR 1‐year patient graft survivals. Methods included all recipients transplant between 2011 2012. excluded younger than 18 years, retransplants who died or lost during index admission. Results Among 1175 recipients, was 26.6%. The main reasons for were...
Background. Mammalian target of rapamycin inhibitors (mTORi), sirolimus (SRL) and everolimus (EVR), have distinct pharmacokinetic/pharmacodynamics properties. There are no studies comparing the efficacy safety de novo use SRL versus EVR in combination with reduced-dose calcineurin inhibitor. Methods. This single-center prospective, randomized study included first kidney transplant recipients receiving a single 3 mg/kg antithymocyte globulin dose, tacrolimus, prednisone, without...
<b><i>Background:</i></b> This analysis compared efficacy, renal function, and histology in kidney transplant recipients receiving tacrolimus (TAC) combined with everolimus (EVR) or mycophenolate (MPS). <b><i>Methods:</i></b> was a retrospective from randomized trial who received single 3 mg/kg dose of rabbit antithymocyte globulin (r-ATG), TAC, EVR, prednisone (PRED; r-ATG/EVR, <i>n</i> = 85), basiliximab (BAS), PRED (BAS/EVR, 102)...
Aims The technique used for classification of membranoproliferative glomerulonephritis ( MPGN ) has been changed from an electron microscopy‐based to immunofluorescence IF )‐based semiquantitative with immunoperoxidase IP staining as a backup option when is not possible. Since data on that matter lacking, our aims were study the interobserver variability, correlation and reclassification based these two techniques. Methods results We retrospectively analysed cases type 1 . repeated performed...
Background. The short-term efficacy and safety of everolimus in combination with tacrolimus have been described several clinical trials. Yet, detailed long-term data comparing the use or mycophenolate kidney transplant recipients receiving are lacking. Methods. This is a 5-y follow-up post hoc analysis prospective trial including 288 patients who were randomized to receive single 3-mg/kg dose rabbit antithymocyte globulin, tacrolimus, (EVR), prednisone (rabbit globulin/EVR, n = 85);...
Optimizing antithymocyte globulin (rATG) dosage is critical for high immunological risk patients undergoing a repeat kidney transplant. This natural retrospective cohort study compared clinical outcomes of two successive cohorts consecutive recipients retransplants receiving 5 x 1 mg/kg (rATG-5, n = 100) or single 3 (rATG-3, 110) dose rATG induction therapy. All had negative complement-dependent cytotoxicity crossmatch and no anti-HLA A, B, DR donor-specific antibodies (DSA). The primary...
Background. There is no consensus on the ideal strategy to treat posttransplant focal segmental glomerulosclerosis. The multiple-target therapy, which consisted of high-dose intravenous cyclosporine, prednisone, and plasmapheresis, showed favorable results. Methods. This single-center, prospective study sought evaluate therapy in an independent cohort patients. Results. Thirteen patients with glomerulosclerosis received therapy. Complete remission was achieved 2 (15.4%), partial another...
Podocyte degenerative changes are common in various kidney diseases, and their accurate identification is crucial for pathologists to diagnose treat such conditions. However, this can be a difficult task, previous attempts automate the of podocytes have not been entirely successful. To address issue, study proposes novel approach that combines pathologists' expertise with an automated classifier enhance podocytopathies. The involved building new dataset renal glomeruli images, some others...
A 56-year-old man was submitted to a simultaneous pancreas-kidney transplant 6 years ago. He received induction therapy with thymoglobulin, and maintenance immunosuppressive regimen consisted of tacrolimus (trough levels 6–8 ng/mL), prednisone mycophenolate. Pulmonary tuberculosis treated in the first year post-transplant. reported cough, nasal congestion, anosmia for at least months. No fever documented. Chest CT normal. Sinus showed opacification right maxillary ethmoidal sinuses without...
Abstract The authors have requested that this preprint be removed from Research Square.
Introduction Kidney retransplant is a high risk procedure, without consensus about the best induction imunnossupression strategy. Only few studies have evaluated these growing proportion patients outcomes, specially in Brazil. Objectives Assess rates of CMV infection/disease, DGF, readmission 30 days and biopssy-proven acute rejection. graft survival after 12 months. kidney function Methods Single-center, open, retrospective, exploratory cohort retransplants performed between -06/16/2014...
Introduction: Human neutrophil antigens 3 (HNA-3a and HNA-3b) are located on choline transporter protein 2 (CTL2) expressed neutrophils, lungs, kidneys other human tissues. Alloantibodies directed against these formed from allogeneic exposure mainly associated with transfusion-related acute lung injury (TRALI) immune neutropenias, however due to the presence of this antigen in renal tissue doubt that HNA-3 alloimmunization may also be involved cases kidney transplant rejection, study...