A5100318201- Microfluidic and Capillary Electrophoresis Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Bio-sensing Technologies
- 3D Printing in Biomedical Research
- Polymer Surface Interaction Studies
- Advanced Sensor and Energy Harvesting Materials
- Electrowetting and Microfluidic Technologies
- Surface Modification and Superhydrophobicity
- Analytical Chemistry and Sensors
- Cancer Cells and Metastasis
- Electrospun Nanofibers in Biomedical Applications
- Advanced Drug Delivery Systems
- Nanofabrication and Lithography Techniques
- Electrohydrodynamics and Fluid Dynamics
- Advanced Materials and Mechanics
- Advancements in Transdermal Drug Delivery
- Biosensors and Analytical Detection
- Hydrogels: synthesis, properties, applications
- Advanced Polymer Synthesis and Characterization
- Analytical Chemistry and Chromatography
- Wound Healing and Treatments
- Carbon Nanotubes in Composites
- biodegradable polymer synthesis and properties
- Modular Robots and Swarm Intelligence
- Digital Holography and Microscopy
Texas Tech University
2016-2025
Chongqing University
2018-2024
Institute of Engineering Thermophysics
2018-2024
Chongqing Medical University
2023-2024
Chongqing Medical and Pharmaceutical College
2024
State Ethnic Affairs Commission
2024
Dalian Maritime University
2024
Yunnan Nationalities University
2024
Jinan University
2020-2023
Wuhan University
2008-2023
This paper reports a microfluidic method for fast continuous synthesis of Janus particles and three-phase with narrow size distribution. Synthesis included emulsification monomer liquids in-situ photoinitiated polymerization multiphase droplets. We show the strategy precise control over structure their structure-dependent assembly in clusters. demonstrate an asymmetric chemical modification surface JPs by conjugating them protein molecules. The ternary were synthesized from largely...
Self-organization of nanoparticles is an efficient strategy for producing nanostructures with complex, hierarchical architectures. The past decade has witnessed great progress in nanoparticle self-assembly, yet the quantitative prediction architecture ensembles and kinetics their formation remains a challenge. We report on marked similarity between self-assembly metal reaction-controlled step-growth polymerization. act as multifunctional monomer units, which form reversible, noncovalent...
The detection of rare circulating tumor cells (CTCs) in the blood cancer patients has potential to be a powerful and noninvasive method for examining metastasis, evaluating prognosis, assessing sensitivity drugs, monitoring therapeutic outcomes. In this study, we have developed an efficient strategy isolate CTCs from breast using microfluidic immune-affinity approach. Additionally, gain further access these downstream characterization, our allows easy detachment captured substrate without...
The direct local delivery of short interfering RNA (siRNA) into target tissues presents a real solution to several complex medical conditions that today lack efficacious therapies. development an ultrathin polymer coating is described sustain the siRNA for up 2 weeks in vitro and vivo. This technology successfully reduces expression MMP-9 within wounds diabetic mice, significantly accelerating wound healing process improving quality tissue formed. As service our authors readers, this journal...
A layer-by-layer gelatin nanocoating is presented for use as a tunable, dual response biomaterial the capture and release of circulating tumor cells (CTCs) from cancer patient blood. The entire can be dissolved surface microfluidic devices through biologically compatible temperature shifts. Alternatively, individual CTCs released locally applied mechanical stress.
We report a study of the continuous generation polymer particles in parallel multiple modular microfluidic (M3) reactors. Each module consisted sixteen reactors comprising emulsification and polymerization compartments. identified minimized effects following factors that could result broadening distribution sizes synthesized M3 reactors, comparison with an individual reactor: (i) fidelity fabrication droplet generators; (ii) crosstalk between generators sharing liquid supply sources; (iii)...
An easy and flexible two-step approach consisting of annealing subsequently selective pitting corrosion has been developed to prepare porous carbonyl iron flakes (CIFs). Based on the dependence morphologies compositions resultant CIFs temperature time, a formation mechanism for substantiated. In our protocol, process carried out as first step in causes an increase grain size forces Fe nanocrystals react with N impurities raw generate dispersed Fe4N domains. These domains induce corrosion,...
Abstract With ethylene glycol as a green solvent, general transition metal‐free photocatalytic system using 9‐mesityl‐10‐methylacridinium perchlorate (Acr + −Mes ⋅ ClO 4 − ) catalyst was developed for the synthesis of sulfone‐containing heterocycles including thioflavones, oxindoles, and quinoline‐2,4(1 H ,3 )‐diones through cascade sulfonation/cyclization reactions under irradiation blue light at room temperature. magnified image
Hydrogels with multifunctional properties such as biocompatibility, adhesion, and self-healing inherent antibacterial are of great significance in biomedical applications, especially for wound dressings drug release. However, it remains a significant challenge to combine all these one-component hydrogel system. Furthermore, most injectable hydrogels mechanically weak not self-healing, which limits their applications dressings. Herein, we designed tunable two-layer structure that endows the...
Lignin from different biomasses possess biological antioxidation and antimicrobial activities, which depend on the number of functional groups molecular weight lignin. In this work, organosolv fractionation was carried out to prepare lignin fraction with a suitable structure tailor excellent activities. Gel permeation chromatography (GPC) analysis showed that decreased fractions were obtained by sequentially anhydrous acetone, 50% acetone 37.5% hexanes. Nuclear magnetic resonance (NMR)...
Although barium titanate (BaTiO
The D antigen includes category D, partial and weak types, which are important because anti-D alloimmunization can occur in some but not all persons that express a variant RHD allele. At present, there is little prospective information on the prevalence of variants among obstetric patients potential transfusion recipients.The alleles were prospectively examined large patient population identified basis difference reactivity between two reagents.Fifty-five discrepancies (0.96% D-) noted...
We report a versatile "inside-out" microfluidic approach to producing monodisperse particle-stabilized emulsions, as well supracolloidal polymer microspheres. This addresses the challenges faced in conventional strategies for preparation of Pickering that is, an insufficient control droplet dimensions and excess particles continuous media. The proposed method minimizes waste particles, due their introduction phase, rather than medium; allows over coverage droplets with by manipulating...
This paper describes geometric coupling of the dynamics break-up liquid threads in parallel flow-focusing devices (FFD), which are integrated into a multiple quadruple-microfluidic droplet generator (QDG). We show weak parametric between FFDs with an identical design, leads to slight broadening distribution sizes droplets. Using distinct geometries we simultaneously generated several populations droplets different volumes, yet, each these was characterized by narrow size distribution....
We report a cost-efficient and easy to implement process for fabricating microfluidic reactors in thermoplastic materials. The method includes (i) the fabrication of an imprint template (master), which consists photoresist deposited on metal plate; (ii) thermoembossing reactor features into polymer sheets; (iii) activation embossed planar surfaces; (iv) low-temperature bonding these surfaces. generality is established by with complex geometry range polymers, including cycloolefin,...
We present a new concept for studies of the kinetics fast gas–liquid reactions. The strategy relies on microfluidic generation highly monodisperse gas bubbles in liquid reaction medium and subsequent analysis time-dependent changes bubble dimensions. Using reactions CO2 with secondary amines as an exemplary system, we demonstrate that method enables rapid determination rate constant conversion, comparison various binding agents. proposed approach addresses two challenges reactions:...
We developed a microfluidic inline digital holography microscopy platform to fingerprint tumor cells in blood based on cell size and optical signatures.
Abstract Smart surfaces that can dynamically respond to environmental stimuli have demonstrated great promise in wearable electronics and optical detectors. Herein, a photopatternable nanolayered polymeric film reversibly display hide structural colors the visible range response relative humidity (RH) changes is reported. This fabricated on silicon substrate using layer‐by‐layer assembly of chitosan photoreactive carboxymethyl cellulose‐azido derivative, selectively crosslinked through UV...
Encapsulation of cells inside microfluidic droplets is central to several applications involving cellular analysis. Although, theoretically the encapsulation statistics are expected follow a Poisson distribution, experimentally this may not be achieved due lack full control experimental variables and conditions. Therefore, there need for automatic detection cell count enumeration within so process feedback adjust conditions can implemented. In study, we use deep learning object detector...