A5021877136- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- Advanced Data Compression Techniques
- Genetic and Kidney Cyst Diseases
- Genetic Associations and Epidemiology
- Renal cell carcinoma treatment
- Advanced Steganography and Watermarking Techniques
- Prostate Cancer Treatment and Research
- Cardiovascular Disease and Adiposity
- Genetics and Neurodevelopmental Disorders
- Multiple and Secondary Primary Cancers
- Pleural and Pulmonary Diseases
- Occupational and environmental lung diseases
- Head and Neck Cancer Studies
- Hormonal Regulation and Hypertension
- Video Coding and Compression Technologies
- Liver physiology and pathology
- Flavonoids in Medical Research
- Traditional Chinese Medicine Analysis
- Ferroptosis and cancer prognosis
- Global Cancer Incidence and Screening
- Diagnosis and treatment of tuberculosis
- Thyroid Disorders and Treatments
- Hippo pathway signaling and YAP/TAZ
Fudan University Shanghai Cancer Center
2024
Fujian Medical University
2024
ETH Zurich
2024
Queen Mary University of London
2021-2024
William Harvey Research Institute
2021-2024
Tzu Chi Foundation
2021-2022
Zhejiang Cancer Hospital
2008-2021
University of Chinese Academy of Sciences
2021
Sir Run Run Shaw Hospital
2019
Zhejiang University
2019
Reduced heart rate (HR) increase (HRI), recovery (HRR), and higher resting HR are associated with cardiovascular (CV) disease, but causal inferences have not been deduced. We investigated effects of HRI, HRR, on CV risk, all-cause mortality (ACM), atrial fibrillation (AF), coronary artery disease (CAD), ischemic stroke (IS) using Mendelian Randomization.11 variants for 11 two sets 46 414 were obtained from four genome-wide association studies (GWASs) UK Biobank. performed a lookup GWASs risk...
The purpose of this study was to investigate the efficacy and safety drug-eluting beads transarterial chemoembolization (DEB-TACE) treatment in Chinese hepatocellular carcinoma (HCC) patients prognostic factors for response as well survival. A total 275 HCC were included prospective study. Treatment assessed by modified Response Evaluation Criteria Solid Tumors (mRECIST), progression-free survival (PFS) overall (OS) determined. Liver function adverse events (AEs) before after DEB-TACE...
This study aimed to investigate the efficacy, safety, and prognostic factors of drug-eluting beads transarterial chemoembolization (DEB-TACE) in treating Chinese patients with liver cancer. A total 367 cancer from 24 medical centers were consecutively enrolled this multiple-center, prospective cohort study, including 275 hepatocellular carcinoma (HCC) cases, 37 intrahepatic cholangiocarcinoma (ICC) 55 secondary cases. All received CalliSpheres ® DEB-TACE treatment. Treatment response,...
Abstract This study aimed to investigate the efficacy and safety of drug-eluting beads (DEB) transarterial chemoembolization (TACE) treatment in Chinese intrahepatic cholangiocarcinoma (ICC) patients. 37 ICC patients underwent DEB-TACE CTILC (registered on clinicaltrials.gov with registry No. NCT03317483) were included this present study. Treatment response was assessed according modified Response Evaluation Criteria Solid Tumors (mRECIST). Overall survival (OS) calculated from time...
Z-ligustilide (or ligustilide) is found in Angelica sinensis (Oliv.) Diels and may exert potential benefits cancer treatment. Previous research has reported that ligustilide anti-cancer effects on several types of cells. However, studies oral cells have not been reported, especially under hypoxic conditions. This study focuses the molecular mechanism ligustilide-induced apoptosis We TW2.6 cells, inhibited cell migration induced caspase-dependent apoptosis. Accumulation c-Myc accompanied by...
Background: The purpose of this study is to evaluate the efficacy transcatheter arterial chemoembolization (TACE) combined with computed tomography-guided radiofrequency ablation (CT-RFA) in treatment hepatocellular carcinoma (HCC) using magnetic resonance diffusion weighted imaging (MR-DWI) and CT perfusion (CT-PI). Methods: From January 2008 2014, a total 522 HCC patients receiving TACE CT-RFA were included study. All underwent followed by CT-RFA, 1 day before month after they received...
In this paper, we propose a new reversible watermarking of medical images for the applications in telemedicine. By using bit-stream insertion scheme, patient’s information can be treated as watermark and embedded into cover image remote transmission. The propos
To evaluate the characteristics of enhancement focal nodular hyperplasia (FNH) liver by analyzing dynamic contrast-enhanced multislice computed tomography (MSCT) features and correlating them with pathological findings.Nine males 16 females pathologically confirmed FNH complete preoperative MSCT data were recruited for this study. The imaging on pre- postcontrast analyzed two experienced radiologists consensus.Pathology showed central scars abnormal blood vessels in 17 21 25 lesions,...
To evaluate the efficacy of transarterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) for both primary and recurrent early-stage hepatocellular carcinoma (HCC) to analyze significant prognostic factors.
Abstract An elevated resting heart rate (RHR) is associated with increased cardiovascular mortality. Genome-wide association studies (GWAS) have identified > 350 loci. Uniquely, in this study we applied genetic fine-mapping leveraging tissue specific chromatin segmentation and colocalization analyses to identify causal variants candidate effector genes for RHR. We used RHR GWAS summary statistics from 388,237 individuals of European ancestry UK Biobank performed fine mapping using...
Background . Accurate and effective biomarkers for the prognosis of patients with hepatocellular carcinoma (HCC) are poorly identified. A network‐based gene signature may serve as a valuable biomarker to improve accuracy risk discrimination in patients. Methods The expression levels cancer hallmarks were determined by Cox regression analysis. Various bioinformatic methods, such GSEA, WGCNA, LASSO, statistical approaches applied generate an MTORC1 signaling‐related (MSRS). Moreover, decision...
Objective To explore the feasibility of CT guided percutaneous incisional needle biopsy （PINB） for deep pelvic masses at different locations via various puncture approaches. Methods PINBs under guidance were performed in 70 patients with 72 lesions through Their pathological findings and safety evaluated after follow-up a period 1-34 months. Results transpiriform-muscle 27 cases, 16 transgluteal approach, 5 posterior oblique approach prone position, 8 by anterior or lateral transabdominal...
(1) Background: In Taiwan, prostate cancer is a major malignancy with an increasing incidence among men. This study explores the medical utilization of emergency departments patients in Taiwan. (2) Methods: nationwide, population-based was conducted via cross-sectional method based on Registry for Catastrophic Illness Patient Database from Taiwan's National Health Insurance Research Database. Patients newly diagnosed between 1997 and 2013 were enrolled divided into four treatment-related...
Background: This study aimed to assess the treatment response, short-term overall survival (OS) and safety profiles of drug-eluting beads transarterial chemoembolization (DEB-TACE) in patients with secondary liver cancer. Methods: Fifty-five cancer underwent DEB-TACE were enrolled this prospective cohort study. Treatment response was assessed by modified Response Evaluation Criteria Solid Tumors (mRECIST). OS calculated from time operation until date death. Results: The complete (CR)...
This study aimed to assess the treatment response, short-term overall survival (OS) and safety profiles of drug-eluting beads transarterial chemoembolization (DEB-TACE) in patients with secondary liver cancer.Fifty-five cancer underwent DEB-TACE were enrolled this prospective cohort study. Treatment response was assessed by modified Response Evaluation Criteria Solid Tumors (mRECIST). OS calculated from time operation until date death.The complete (CR) objective rate (ORR) at 1-3 months post...
Abstract Background Androgen deprivation therapy (ADT) is the major treatment for metastatic prostate cancer (PCa), but few studies have investigated effects of ADT on thyroid diseases. Methods This population‐based, nationwide cohort study utilized Taiwan National Health Insurance Research Database (NHIRD) with 17,192 PCa patients between 1997 and 2013. We used Cox proportional hazards models propensity score‐matched analysis to analyze association development Results A total newly...