A5024277943- Pain Mechanisms and Treatments
- Osteoarthritis Treatment and Mechanisms
- Proteoglycans and glycosaminoglycans research
- Tendon Structure and Treatment
- Dermatologic Treatments and Research
- Muscle Physiology and Disorders
- Amyotrophic Lateral Sclerosis Research
- Neurogenetic and Muscular Disorders Research
- Adipose Tissue and Metabolism
- Neuroinflammation and Neurodegeneration Mechanisms
- Diagnosis and Treatment of Venous Diseases
- Biochemical effects in animals
- RNA regulation and disease
- Stress Responses and Cortisol
- Olfactory and Sensory Function Studies
- Parkinson's Disease Mechanisms and Treatments
- MicroRNA in disease regulation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Memory and Neural Mechanisms
- Exercise and Physiological Responses
- Neurological Disorders and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Rheumatoid Arthritis Research and Therapies
- Dermatology and Skin Diseases
- Facial Rejuvenation and Surgery Techniques
University of Ferrara
2022-2024
British American Tobacco (United Kingdom)
2023
Benemérita Universidad Autónoma de Puebla
2021
Charles River Laboratories (United Kingdom)
2020
Concrete Repairs (United Kingdom)
2020
Torbay and South Devon NHS Foundation Trust
2019
University of Sheffield
2013-2018
University of Leeds
2011-2018
University of Bristol
2018
University of Kentucky
2012-2017
Parkinson's disease (PD) is a progressive neurodegenerative disorder which may be misdiagnosed with atypical conditions such as Multiple System Atrophy (MSA), due to overlapping clinical features. MicroRNAs (miRNAs) are small non-coding RNAs key role in post-transcriptional gene regulation. We hypothesized that identification of distinct set circulating miRNAs (cmiRNAs) could distinguish patients affected by PD from MSA and healthy individuals. Results. Using TaqMan Low Density Array...
Abstract Background Multiple sclerosis (MS), a demyelinating disease of the central nervous system, is one most prevalent neurological disorders in industrialized world. This afflicts more than two million people worldwide, over thirds which are women. MS typically diagnosed between ages 20–40 and can produce debilitating impairments including muscle spasticity, paralysis, chronic pain. Despite large sex disparity prevalence, clinical basic research investigations how estrous cycle impact...
Background: Pulsed electromagnetic field (PEMF) therapy has shown promising therapeutic effectiveness on bone- and cartilage-related pathologies, being also safe for management of knee osteoarthritis. Aim: The aim this study was to investigate the clinical efficacy a PEMF device osteoarthritis in elderly patients. Materials methods: A total 33 patients were screened, 28 patients, aged between 60 83 affected by bilateral osteoarthritis, enrolled study. They received right leg three 30-minute...
Multiple sclerosis (MS) is an autoimmune-inflammatory neurodegenerative disease that often accompanied by a debilitating neuropathic pain. Disease-modifying agents slow down the progression of multiple and prevent relapses, yet it remains unclear if they yield analgesia. We explored analgesic potential fingolimod (FTY720), agonist and/or functional antagonist at sphingosine-1-phosphate receptor 1 (S1PR1), because reduces hyperalgesia in models peripheral inflammatory used myelin...
J Oral Pathol Med (2012) 41 : 649–661 Free radicals play a key role in the development of several pathological conditions. Therefore, methods have been developed to measure oxidative stress from bodily fluids including blood, urine and, more recently, saliva. radical and antioxidant defences within oral cavity may odontostomatological pathologies. This review provides an update literature concerning association with conditions associated cavity. It focuses on diagnostic therapeutic...
Abstract Background hyaluronic acid (HA), a non-sulphated glycosaminoglycan, is present in synovial fluid, vitreous humour serum and many connective tissues. Pharmaceutical preparations of HA are used clinical practice for wound healing, joint pain, kerato-conjunctivitis, asthma, mouth care, oesophageal-reflux, gastritis. Moreover, it as filler to counteract ageing facial lipoatrophy. Our study aims at investigating the vitro antiviral activity high molecular weight HA. Methods MTT test was...
This study investigated whether sensitivity to nociceptive stimuli is altered in obese rats using established models of inflammatory pain, and real-time PCR, profiled alterations expression key adipokine mediator mRNA (adiponectin, tumor necrosis factor-α, interleukin-1β, cyclooxygenase-2, inducible nitric oxide synthase (iNOS)) spinal cord with obesity. Responses thermal mechanical stimulation the hindpaw paw oedema were assessed adult male Zucker fatty (fa/fa) their lean littermates (fa/-;...
Excessive exposure to the sun can cause severe photoaging as early second decade of life resulting in a loss physiological elastic fiber functions. We designed first study assess differences facial skin pH, sebum, elasticity, hydration and tonicity serum levels fibronectin, elastin, neutrophil elastase 2, hyaluronic acid carbonylated proteins between patients affected by healthy controls. In we tested hypothesis that dietary supplement would improve photoaging, also promoting changes above...