Fenghua Geng

ORCID: 0000-0002-4763-8445
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • DNA and Nucleic Acid Chemistry
  • Molecular Sensors and Ion Detection
  • RNA Interference and Gene Delivery
  • Advanced Nanomaterials in Catalysis
  • Luminescence and Fluorescent Materials
  • Sulfur Compounds in Biology
  • Nanocluster Synthesis and Applications
  • Nanoplatforms for cancer theranostics
  • Biosensors and Analytical Detection
  • Carbon and Quantum Dots Applications
  • Analytical Chemistry and Sensors
  • Catalysis and Hydrodesulfurization Studies
  • Graphene and Nanomaterials Applications
  • Ionic liquids properties and applications
  • Synthetic Organic Chemistry Methods
  • Petroleum Processing and Analysis
  • Electrochemical sensors and biosensors
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Asymmetric Synthesis and Catalysis
  • Asymmetric Hydrogenation and Catalysis

Shangqiu Normal University
2012-2024

China University of Mining and Technology
2020-2022

China University of Petroleum, Beijing
2021

Shangqiu Institute of Technology
2015

A dual-signal sensing system based on the inner-filter effect (IFE) was demonstrated, in which combination of two signaling mechanisms allows metal binding to turn fluorescence emission bands, independently. proof-of-concept fluorescent ratiometric assay for Al3+ pure aqueous solution is presented. The proposed Al3+-induced color and changes Alizarin red S (ARS) IFE between ARS meso-tetra(N-methyl-4-pyridyl)porphine tetratosylate salt (TMPyP). In absence Al3+, absorption spectrum 0.2 M...

10.1039/c1an15566k article EN The Analyst 2011-01-01

A G-quadruplex molecular switch (G4-MS) assembled using auramine O and the G-rich single stranded DNA is developed for a assay.

10.1039/c5cc02624e article EN Chemical Communications 2015-01-01

Binding-induced quenching of AMT to G-quadruplex is used for the first time design an improved fluorescent Pb<sup>2+</sup> aptasensor.

10.1039/d0cc03669b article EN Chemical Communications 2020-01-01

A novel fluorescent Hg2+ sensor was developed based on the T–Hg2+–T structure and a thioflavine T monomer–excimer switch. Under optimum conditions, selectivity is remarkably high, can be quantified over dynamic range of 0.1 to 1.2 μM, with limit detection (LOD) ∼20 nM linear correlation coefficient 0.995.

10.1039/c1an15465f article EN The Analyst 2011-01-01

A sensing ensemble for cysteine was assembled conveniently by simply mixing curcumin (Cur) and Hg2+ in buffered acetonitrile/HEPES (10 mM, 7/3, v/v, pH 7.4) solutions. In the ensemble, serves as receptor, Cur functions indicator analyte. The detection can be performed either spectroscopically, decrease of UV-Vis absorbance at 430 nm increase 355 nm, or visually color change from colorless to yellow upon addition an aqueous solution analyte ensemble.

10.1039/c3ay40550h article EN Analytical Methods 2013-01-01

A novel fluorescent aptasensor based on the G-quadruplex induced quenching of psoralen and competitive interactions between 4'-aminomethyl-4,5',8-trimethylpsoralen (AMT), adenosine triphosphate (ATP) G-rich DNA functionalized split ATP aptamer was proposed. The binding to a significant enhancement in fluorescence emission intensity while undergoing excitation at 340 nm. Under optimal conditions, developed showed high selectivity good accuracy for detecting ATP. practicality proposed has been...

10.2116/analsci.19p455 article EN Analytical Sciences 2020-02-13

This communication demonstrates the feasibility of using Mn 2+ -triggered aggregation-induced emission transformation levodopa fluorescent copolymer nanoparticles as a direct in situ alkaline phosphatase-labeled luminescent nanoimmunoassay platform.

10.1039/d4ay00973h article EN Analytical Methods 2024-01-01

Alkaline phosphatase (ALP)-induced in situ fluorescent immunosensor is less investigated and reported. Herein, a high-performance ALP-labeled immunoassay platform was constructed. The developed based on fluorogenic self-assembly reaction between pyridineboronic acid (PyB(OH)2) alizarin red S (ARS). We first used density functional theory (DFT) to theoretically calculate the changes of Gibbs free energy chemicals before after combination simulated electrostatic potential its′ surfaces. ARS...

10.2139/ssrn.4253425 article EN SSRN Electronic Journal 2022-01-01
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