- Advanced biosensing and bioanalysis techniques
- DNA and Nucleic Acid Chemistry
- Molecular Sensors and Ion Detection
- RNA Interference and Gene Delivery
- Advanced Nanomaterials in Catalysis
- Luminescence and Fluorescent Materials
- Sulfur Compounds in Biology
- Nanocluster Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Biosensors and Analytical Detection
- Carbon and Quantum Dots Applications
- Analytical Chemistry and Sensors
- Catalysis and Hydrodesulfurization Studies
- Graphene and Nanomaterials Applications
- Ionic liquids properties and applications
- Synthetic Organic Chemistry Methods
- Petroleum Processing and Analysis
- Electrochemical sensors and biosensors
- Gold and Silver Nanoparticles Synthesis and Applications
- Asymmetric Synthesis and Catalysis
- Asymmetric Hydrogenation and Catalysis
Shangqiu Normal University
2012-2024
China University of Mining and Technology
2020-2022
China University of Petroleum, Beijing
2021
Shangqiu Institute of Technology
2015
A dual-signal sensing system based on the inner-filter effect (IFE) was demonstrated, in which combination of two signaling mechanisms allows metal binding to turn fluorescence emission bands, independently. proof-of-concept fluorescent ratiometric assay for Al3+ pure aqueous solution is presented. The proposed Al3+-induced color and changes Alizarin red S (ARS) IFE between ARS meso-tetra(N-methyl-4-pyridyl)porphine tetratosylate salt (TMPyP). In absence Al3+, absorption spectrum 0.2 M...
A G-quadruplex molecular switch (G4-MS) assembled using auramine O and the G-rich single stranded DNA is developed for a assay.
Binding-induced quenching of AMT to G-quadruplex is used for the first time design an improved fluorescent Pb<sup>2+</sup> aptasensor.
A novel fluorescent Hg2+ sensor was developed based on the T–Hg2+–T structure and a thioflavine T monomer–excimer switch. Under optimum conditions, selectivity is remarkably high, can be quantified over dynamic range of 0.1 to 1.2 μM, with limit detection (LOD) ∼20 nM linear correlation coefficient 0.995.
A sensing ensemble for cysteine was assembled conveniently by simply mixing curcumin (Cur) and Hg2+ in buffered acetonitrile/HEPES (10 mM, 7/3, v/v, pH 7.4) solutions. In the ensemble, serves as receptor, Cur functions indicator analyte. The detection can be performed either spectroscopically, decrease of UV-Vis absorbance at 430 nm increase 355 nm, or visually color change from colorless to yellow upon addition an aqueous solution analyte ensemble.
A novel fluorescent aptasensor based on the G-quadruplex induced quenching of psoralen and competitive interactions between 4'-aminomethyl-4,5',8-trimethylpsoralen (AMT), adenosine triphosphate (ATP) G-rich DNA functionalized split ATP aptamer was proposed. The binding to a significant enhancement in fluorescence emission intensity while undergoing excitation at 340 nm. Under optimal conditions, developed showed high selectivity good accuracy for detecting ATP. practicality proposed has been...
This communication demonstrates the feasibility of using Mn 2+ -triggered aggregation-induced emission transformation levodopa fluorescent copolymer nanoparticles as a direct in situ alkaline phosphatase-labeled luminescent nanoimmunoassay platform.
Alkaline phosphatase (ALP)-induced in situ fluorescent immunosensor is less investigated and reported. Herein, a high-performance ALP-labeled immunoassay platform was constructed. The developed based on fluorogenic self-assembly reaction between pyridineboronic acid (PyB(OH)2) alizarin red S (ARS). We first used density functional theory (DFT) to theoretically calculate the changes of Gibbs free energy chemicals before after combination simulated electrostatic potential its′ surfaces. ARS...