A5035539073- Genomics and Phylogenetic Studies
- Gut microbiota and health
- Vector-borne infectious diseases
- Clostridium difficile and Clostridium perfringens research
- Phytoplasmas and Hemiptera pathogens
- Chromosomal and Genetic Variations
- Genetic diversity and population structure
- Infant Nutrition and Health
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Pediatric health and respiratory diseases
- Plant Virus Research Studies
- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
Microbiology Institute of Shaanxi
2024
Institute of Microbiology
2021-2024
Chinese Academy of Sciences
2021-2024
State Key Laboratory of Microbial Resources
2024
Tianjin University
2020-2022
Autism spectrum disorders (ASDs) are a set of complex neurobiological disorders. Growing evidence has shown that the microbiota resides in gut can modulate brain development via gut-brain axis. However, direct clinical role microbiota-gut-brain axis ASD is relatively limited.A case-control study 71 boys with and 18 neurotypical controls was conducted at China-Japan Friendship Hospital. Demographic information fecal samples were collected, microbiome evaluated compared by 16S ribosomal RNA...
Abstract Background In the present study, we used long-PCR amplification coupled with Next-Generation Sequencing (NGS) to obtain complete mitochondrial (mt) genomes of individual ticks and unprecedently performed precise annotation these mt genomes. We aimed to: (1) develop a simple, cost-effective accurate method for study extremely high AT-content within an animal (e.g. Dermacentor silvarum ) containing miniscule DNA; (2) provide high-quality reference genome D. also future studies other...
Dysregulation of the gut microbiome has been implicated in progression many diseases. This study explored role microbial and metabolic signatures, their interaction between Human inflammatory bowel disease (IBD) healthy controls (HCs) based on combination machine learning traditional statistical analysis, using data collected from Microbiome Project (HMP) Integrative (iHMP). It was showed that signatures IBD patients were significantly different those HCs. Compared to HCs, subjects...
ABSTRACT In China, 45% of adolescents with obesity develop fatty liver disease, a condition that increases the long-term risk developing cirrhosis and cancer. Although factors triggering nonalcoholic disease (NAFLD) vary in children, composition intestinal microflora has been found to play an increasingly important role. However, evidence is limited on prevalence (NAFL) steatohepatitis (NASH) Chinese children. Therefore, this study aimed evaluate fecal microbiome children NAFLD further...
Abstract Background: In the present study, we used long-PCR amplification coupled with Next-Generation Sequencing (NGS) to obtain complete mitochondrial (mt) genomes of individual ticks and unprecedently performed precise annotation these mt genomes. We aimed to: (1) develop a simple, cost-effective accurate method for study extremely high AT-content within an animal containing miniscule DNA (e.g. Dermacentor silvarum); (2) provide high-quality reference genome D. silvarum also future...
To explore the effect of gestational diabetes mellitus on gut microbiota their offsprings, 3-month-old infants whose mothers diagnosed with and without mellitus(GDM) was compared.Pregnant women who were examined, delivered follow-up visited in a county Hebei Province from June 2016 to December 2019 included our study. The pregnants result fasting venous blood glucose≥5.1 mmol/L second or third trimester GDM group. Fecal samples collected 16 S rDNA high-throughput sequencing technology used...
Abstract Background : In the present study, we used long-PCR amplification coupled with Next-Generation Sequencing (NGS) to obtain complete mitochondrial (mt) genomes of individual ticks and unprecedently performed precise annotation these mt genomes. We aimed to: (1) develop a simple, cost-effective accurate method for study extremely high AT-content within an animal (e.g. Dermacentor silvarum ) containing miniscule DNA; (2) provide high-quality reference genome D. also future studies other...
Abstract In the present study, we performed precise annotation of Drosophila melanogaster , D. simulans grimshawi Bactrocera oleae mitochondrial (mt) genomes by pan RNA-seq analysis. Our new annotations corrected or modified some previous and two important findings were reported for first time, including discovery conserved polyA(+) polyA(−) motifs in control regions (CRs) insect mt adding CCAs to 3’ ends antisense tRNAs genome. Using PacBio cDNA-seq data from precisely annotated...