- Cognitive Functions and Memory
- Parkinson's Disease Mechanisms and Treatments
- Dementia and Cognitive Impairment Research
- Neural and Behavioral Psychology Studies
- Neurological disorders and treatments
- Attention Deficit Hyperactivity Disorder
- Psychosomatic Disorders and Their Treatments
- Autism Spectrum Disorder Research
- Traumatic Brain Injury Research
- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Pharmacological Effects and Toxicity Studies
- Action Observation and Synchronization
- Transcranial Magnetic Stimulation Studies
- Balance, Gait, and Falls Prevention
- Obsessive-Compulsive Spectrum Disorders
- Neurobiology of Language and Bilingualism
- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Migraine and Headache Studies
- COVID-19 and Mental Health
- Pregnancy and Medication Impact
- Neuroscience and Neuropharmacology Research
- Cardiac Arrest and Resuscitation
- Memory and Neural Mechanisms
Fondazione Santa Lucia
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2025
University Niccolò Cusano
2015-2025
Universidade Estadual de Campinas (UNICAMP)
2004-2022
Italian University Line
2018
Cambridge University Press
2017
International Society of Nephrology
2017
University of Rome Tor Vergata
2010-2015
Masimo (United States)
2014
Hospital de Clínicas da Unicamp
2014
Among Parkinson's disease (PD) symptoms, freezing of gait (FoG) is one the most debilitating. To assess FoG, current clinical practice mostly employs repeated evaluations over weeks and months based on questionnaires, which may not accurately map severity this symptom. The use a non-invasive system to monitor activities daily living (ADL) PD symptoms experienced by patients throughout day could provide more accurate objective evaluation FoG in order better understand evolution allow for...
The COVID-19 pandemic and government imposed social restrictions like lockdown exposed most individuals to an unprecedented stress, increasing mental health disorders worldwide. We explored subjective cognitive functioning changes their possible interplay related COVID-19-lockdown. also investigated potential risk factors identify more vulnerable groups. Across Italy, 1215 respondents completed our Qualtrics-based online-survey during the end of a seven 10-week home confinement (from April...
Aims of this study were (i) to verify whether a deficit or lack self-awareness can lead difficulties in assuming another person's perspective after severe traumatic brain injury (TBI); (ii) perspective-taking deficits emerge more from performance-based tasks than self-reports; and (iii) evaluate the possible relationships between some clinical, neuropsychological, neuropsychiatric, neuroimaging variables. The Interpersonal Reactivity Index, Empathy Quotient, first-order false-belief, faux...
Parkinson's disease (PD) patients, besides motor dysfunctions, may also display mild cognitive deficits (MCI) which increase with progression. The neurotrophin brain-derived neurotrophic factor (BDNF) plays a role in the survival of dopaminergic neurons and regulation synaptic connectivity. Moreover, brain peripheral level this protein be significantly reduced PD patients. These data suggest that rehabilitation protocol aimed at restoring patients involve changes neurotrophin. Thus, pilot...
Brain-derived neurotrophic factor (BDNF) is a trophic regulating cell survival and synaptic plasticity. Recent findings indicate that BDNF could be potential regulatory for cognitive functioning in normal and/or neuropathological conditions. With regard to neurological disorders, recent data suggest individuals with Parkinson's disease (PD) may affected by deficits they have altered production. Therefore, the hypothesis can advanced levels are associated state of these patients. this mind,...
Background Our group earlier developed a small monitoring device, which uses accelerometer measurements to accurately detect motor fluctuations in patients with Parkinson's (On and Off state) based on an algorithm that characterizes gait through the frequency content of strides. To further validate algorithm, we studied correlation its outputs section Unified Disease Rating Scale (UPDRS-III). Method Seventy-five suffering from disease were asked walk both On phase while wearing inertial...
Visual-spatial working memory (WM) impairment is frequently associated with the early stage of Parkinson’s disease (PD). The aim this study was to evaluate performance a group PD patients in visual-spatial and visual-object WM tasks investigate effect administering dopaminergic agonist apomorphine (experiment 1) or dopamine precursor <i>L</i>-dopa 2) on tests assessing these functions. To processes, age-matched normal controls were given an n-back task paradigm. In both...
Stroke patients suffer from a high rate of behavioral disorders, and the laterality lesion may affect expression emotional disturbances. This study tested hypothesis that stroke with in right hemisphere are at risk developing alexithymic features.Forty-eight were interviewed Structured Clinical Interview for DSM-IV (patient edition), Mini-Mental State Examination, State-Trait Anxiety Inventory (state form), Beck Depression Inventory, Toronto Alexithymia Scale (20-item version). Alexithymic...
This study investigated prospective memory and its relationship to executive functions in persons with Parkinson's disease (PD). Twenty-three individuals PD 25 healthy comparison participants participated the study. In tasks, were asked execute 3 actions after 20 min (time-based condition) or a timer ring (event-based condition). A score was computed for correct recall of intention perform (prospective component) execution (retrospective component). Participants also received an extensive...
Primary Objective: The primary aim of this study was to determine the frequency severe impaired self-awareness (ISA) in patients with traumatic brain injury (TBI) and correlates selected clinical, neuropsychiatric cognitive variables. secondary assess depression apathy on basis their level self-awareness.Methods: Thirty TBI 30 demographically matched healthy control subjects (HCs) were compared measures ISA, depression, anxiety, alexithymia, symptoms flexibility.Results: Twenty percent...
Understanding the mental states of others entails a number cognitive processes known as Theory Mind (ToM). Behavioural and functional neuroimaging evidence suggests that prefrontal temporo-parietal cortices are involved in these abilities. The present study was aimed at investigating role dorsolateral cortex junction ToM by using repetitive transcranial magnetic stimulation (rTMS) paradigm.Eleven healthy subjects participated study. experimental procedure constituted false belief faux-pas...