Vipul T. Lakhani

ORCID: 0000-0002-4784-963X
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About
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Research Areas
  • Neuroendocrine Tumor Research Advances
  • Thyroid Cancer Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • BRCA gene mutations in cancer
  • Pituitary Gland Disorders and Treatments
  • Genetic factors in colorectal cancer
  • Ovarian cancer diagnosis and treatment
  • Lung Cancer Research Studies
  • Ion channel regulation and function
  • Pharmacology and Obesity Treatment
  • Gastrointestinal Tumor Research and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Gestational Trophoblastic Disease Studies
  • Medical Imaging and Pathology Studies
  • Colorectal Cancer Screening and Detection
  • Thyroid Disorders and Treatments
  • Soft tissue tumor case studies
  • Endometrial and Cervical Cancer Treatments
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Cardiovascular Syncope and Autonomic Disorders
  • Multiple Myeloma Research and Treatments
  • Cancer-related Molecular Pathways
  • Thyroid and Parathyroid Surgery
  • Sphingolipid Metabolism and Signaling
  • Lipid Membrane Structure and Behavior

Oregon Medical Research Center
2016

Vanderbilt University Medical Center
2006-2013

Diabetes Australia
2013

Vanderbilt University
2006-2012

Tennessee Oncology
2008

Duke University
2007

Duke Medical Center
1995-2006

Institut Gustave Roussy
2006

Duke University Hospital
1995-2006

AstraZeneca (United States)
2006

Our purpose was to evaluate the safety and efficacy of (68)Ga-DOTATATE PET/CT compared with (111)In-pentetreotide imaging for diagnosis, staging, restaging pulmonary gastroenteropancreatic neuroendocrine tumors.(68)Ga-DOTATATE scans were obtained 78 97 consecutively enrolled patients known or suspected tumors. Safety toxicity measured by comparing vital signs, serum chemistry values, acquisition-related medical complications before after injection. Added value determined changes in treatment...

10.2967/jnumed.115.163865 article EN Journal of Nuclear Medicine 2016-01-14

Lenalidomide is an antiangiogenic drug associated with hypothyroidism. We describe a case-series of lenalidomide use in hematological cancers and the prevalence thyroid abnormalities. reviewed medical records patients treated at single center form 2005 to 2010 extracted demographic, clinical, laboratory data. Of 170 confirmed (age 64.9 ± 15 years), 148 were for multiple myeloma 6% had abnormalities attributable only lenalidomide. In previous diagnosis dysfunction, addition therapy was higher...

10.1002/ajh.22008 article EN American Journal of Hematology 2011-02-18

5533 Background: Medullary thyroid carcinoma (MTC) is the most common cause of death in patients with hereditary syndromes caused by specific mutations RET protooncogene. activation oncogenic event, which results intrinsic receptor tyrosine kinase activity, but other pathways, such as VEGFR- and EGFR-dependent signaling, also participate tumor growth development. ZD6474 a once-daily oral agent that selectively targets RET, VEGFR EGFR kinases. The clinical activity was evaluated MTC. Methods:...

10.1200/jco.2006.24.18_suppl.5533 article EN Journal of Clinical Oncology 2006-06-20

Sphingolipid-gated Ca2+ signaling is mediated through Ca2+-permeable channels. In this report, we characterize the properties of channel in a human endothelial cell line (EA.hy926). release from intracellular stores not antagonized by nifedipine, ω conotoxin G-VIa, or heparin. To further molecular channel, developed novel assay to directly measure efflux permeabilized Xenopus oocytes. Following size fractionation sucrose gradient, poly(A)+ RNA EA.hy926 cells microinjected into oocytes...

10.1074/jbc.270.10.5266 article EN cc-by Journal of Biological Chemistry 1995-03-01

10.1016/j.jamcollsurg.2007.06.323 article EN Journal of the American College of Surgeons 2007-10-01

This case report describes a woman treated for stage 1 B grade 3 endometrial adenocarcinoma with surgery and adjuvant radiation therapy who presented 6 months later pain symptoms of adrenal insufficiency. A large right mass revealed consistent the primary.

10.1155/2013/428456 article EN cc-by Case Reports in Surgery 2013-01-01

10.1007/s00268-007-9426-3 article World Journal of Surgery 2008-02-22
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