Introduction: Asthma is the most common respiratory disorder in children.Knowledge about asthma helps achieving control.Self-management of disease includes adherence to medication, avoidance trigger factors, and appropriate response symptoms Education essential improve health reduce negative impact on daily life.Materials Methods: In this study, 62 patients aged 14.04 ± 2.25 years, who had been followed up for at least 6 months Dokuz Eylül University Pediatric Allergy Immunology outpatient...

Accurate use of adrenaline auto-injectors (AAIs) for anaphylaxis is critical to decrease mortality and morbidity.In this study, we aimed assess user knowledge AAIs evaluate the factors that affect their correct use.The study involved caregivers pediatric patients diagnosed with who were trained trainer injectors up 24 months ago. The demographics caregivers, history patients, usage in case anaphylaxis, reasons not using evaluated. Users asked demonstrate Penepin® a injector.Fifty-nine...

Nicolau syndrome (NS) is a rare complication of intramuscular, intraarticular or subcutaneous injection particular drugs leading to ischemic necrosis the surrounding skin, soft tissue and muscular tissue. Benzathine penicilin one most widely used antibiotic for upper respiratory tract infections has been rarely reported cause NS. Here we describe 4 year old boy with diagnosis NS after benzathine penicillin who was successfuly treated unfractionized heparin (enoxaparine) pentoxifylline. The...

Objective: One of the most frequently investigated epigenetic factors in pathogenesis atopic dermatitis (AD) is food.There are different views on effects micronutrients AD development and disease severity.In our study, we aimed to determine feeding style micronutrient levels investigate their relationship with clinical scores infants AD. Materials Methods:We determined serum vitamin A, B12, D, E, zinc, iron at time presentation pediatric allergy clinic.We recorded types infants.The between...

Allergic bronchopulmonary aspergillus (ABPA) is a lung disease caused by hypersensitivity from Aspergillus fumigatus. Diagnostic criteria, staging systems and treatment methods for ABPA have been reported in studies evaluating populations, the majority of which are adult patients. Our study aimed to discuss use diagnostic criteria children, success other alternative regimens oral corticosteroids ABPA, changes that occur during treatment, light literature.Between January 2017 2020, patients...

Background: In recent years, the epithelial barrier hypothesis has been emphasized in formation of allergic diseases. Transepidermal water loss (TEWL) occurs through diffusion and evaporation from skin to external environment. There are few studies on TEWL Objective: This study evaluated relationship between patients with atopic diseases healthy controls hygiene habits TEWL. Methods: The was conducted who were followed up for disease (asthma, rhinitis, immunoglobulin E mediated food allergy,...

Cystic fibrosis is a life-shortening disease characterized by the mutation of salt transporter cystic transmembrane conductance regulator (CFTR) protein.Elexacaftor/tezacaftor/ivacaftor treatment, which has been used since 2019, had effects such as improving quality life, respiratory functions, and reducing rate pulmonary exacerbations.The real-life side drug are still emerging due to new use modulator therapies their spread around world.There no proven protocols regarding these...

Abstract Objective A misdiagnosed “penicillin allergy” is a common problem in childhood. Recently, skipping skin tests (STs) and performing direct oral challenge test (OCT) have become an increasingly approach children with suspected β-lactam (BL) allergy. In our study, we aimed to evaluate the safety efficacy of OCT without using ST who had history hypersensitivity reactions BL antibiotics. Materials Methods We retrospectively evaluated outcomes both nonimmediate immediate-type reaction STs...

Primary immune deficiencies (PIDs) are rare genetic disorders characterized by impaired function, leading to frequent infections and dysregulation. Studies have shown that individuals with PID at an increased risk of developing malignancies lymphoproliferative compared the general population. In this single-center study, we aimed analyze occurrence lymphoproliferations in children diagnosed PID. We retrospectively analyzed medical records 550 pediatric patients PIDs our center. Among them,...

ÖzNeonatal akut solunum sıkıntısı sendromu (ARDS), nispeten yeni bir tanıdır.Altta yatan hastalığın tedavisinden başka, özgül tedavi

Anaphylaxis is a severe systemic hypersensitivity reaction that usually has rapid onset and can be fatal. Presentations of childhood anaphylaxis vary widely in accordance with the triggers patient's age, geographical region dietary lifestyle habits.

Aim: Atopic dermatitis (AD) is a chronic, itchy inflammatory skin disease. This study aimed to examine the clinical features, investigate laboratory test results, and evaluate disease prognosis using allergy tests in patients with AD. Materials Methods: retrospective analyzed patient demographics, characteristics, data, including serum eosinophils, total IgE, other immunoglobulin (Ig) levels, prick patch results. Results: A of 564 were diagnosed AD, whom 343 (60.8%) boys. Skin positive 138...

Atopic dermatitis (AD) is a chronic skin disease caused by genetic and environmental factors. Often it begins in early childhood. It located at the first step of process we refer to as atopic march. This feature precursor development other allergic diseases such asthma rhinitis. Especially patients with atopy food inhalant allergens, occurrence more common. Although role these sensitivities AD controversial, has been determined that some may trigger eczematous lesions. In this report,...

Stridor is divided into two groups as acute and chronic based on its onset duration.Stridor with an manifests within minutes, hours, or days (subacute) usually progresses rapidly.Foreign body aspiration, anaphylaxis, bacterial tracheitis, epiglottitis, laryngotracheitis (croup), retropharyngeal abscess, peritonsillar abscess airway burns may cause stridor.Chronic stridor typically caused by a congenital acquired structural abnormality that leads to obstruction of the upper from inside...

Vaccines, which make it possible to be protected from many life-threatening infectious diseases, have been used safely and effectively for years. Most vaccines today contain a variety of adjuvants exogenous proteins. Severe reactions, in addition transient self-limiting mild mostly caused by these components, reported. The effects vaccine on the pathogenesis immunemediated diseases are still under investigation. syndrome called Autoimmune/inflammatory induced (ASIA) has defined literature.We...

Cystic fibrosis (CF) is an inherited autosomal recessive disorder that causes chronic airway disease. In addition to genetic factors, environmental factors may affect the clinical phenotype of CF. this study, presence aeroallergen sensitivity in our patients with CF and its effects on findings are evaluated.In included were diagnosed followed Pediatric Respiratory Allergy Clinic Faculty Medicine, Dokuz Eylul University, Izmir, Turkey. Demographic characteristics, laboratory findings, skin...

Atopic dermatitis is a chronic, recurrent inflammatory skin disease usually caused by genetic predisposition, immune dysregulation, epidermal barrier dysfunction and interaction of environmental factors. part atopic march often accompanied food allergy. Aeroallergenic sensitization at early age not an expected finding. Here, we present five cases with moderate-severe during infancy, in whom allergy was detected the symptoms improved only partially despite elimination treatment. Sensitization...

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Objective: The prevalence of food allergy (FA) has gradually increased. Bloody stool is among the symptoms associated with non-immunoglobulin E (IgE) mediated FA in infants. In our study, we shared clinical characteristics patients who applied to clinic bloody stool. Material and Methods: data were reviewed. Patients’ time onset tolerance recorded, retrospectively. Results: 110 patient files 68% diagnosed (63 proctocolitis/12 enterocolitis), 22% an anal fissure, 9% nonspecific colitis. most...

Background: Respiratory system involvement is common in congenital plasminogen deficiency. Although many treatment approaches have been tried, there still no definitive for respiratory involvement. Observation(s): We report 2 deficiency cases, who presented with severe symptoms, whom a novel modality was tried. After intravenous administration of FFP (fresh frozen plasma), tissue activator and were administered intratracheally, findings improved. Conclusions: Intratracheal an available...