Yong Chen

ORCID: 0000-0002-4846-7131
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About
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Research Areas
  • Advanced Memory and Neural Computing
  • Neuroscience and Neural Engineering
  • Neural dynamics and brain function
  • Ferroelectric and Negative Capacitance Devices
  • Conducting polymers and applications
  • Photoreceptor and optogenetics research
  • Analytical Chemistry and Sensors
  • Semiconductor materials and devices
  • Advanced biosensing and bioanalysis techniques
  • Molecular Junctions and Nanostructures
  • CCD and CMOS Imaging Sensors
  • Neural Networks and Reservoir Computing
  • Microfluidic and Bio-sensing Technologies
  • Advanced Biosensing Techniques and Applications
  • Transition Metal Oxide Nanomaterials
  • Nanofabrication and Lithography Techniques
  • Perovskite Materials and Applications
  • Quantum-Dot Cellular Automata
  • Force Microscopy Techniques and Applications
  • Advancements in Battery Materials
  • Advanced Power Amplifier Design
  • Influenza Virus Research Studies
  • Biosensors and Analytical Detection
  • T-cell and B-cell Immunology
  • Click Chemistry and Applications

University of California, Los Angeles
2013-2025

California NanoSystems Institute
2007-2025

Samueli Institute
2024

University of Macau
2022

Chemnitz University of Technology
2021

Hubei University
2018

University of California System
2015

UCLA Health
2010

Northwestern University
2008

Nanjing University
2007

Molecular electronics offer an alternative pathway to construct nanoscale circuits in which the critical dimension is naturally associated with molecular sizes. We describe fabrication and testing of molecular-electronic that comprise a monolayer [2]rotaxanes sandwiched between metal nanowires form 8 × crossbar within 1 µm2 area. The resistance at each cross point can be switched reversibly. By using as active memory cell, were operated rewritable, nonvolatile density 6.4 Gbits cm−2. setting...

10.1088/0957-4484/14/4/311 article EN Nanotechnology 2003-03-20

A synaptic transistor is fabricated by integrating ionic/electronic hybrid materials to emulate biological synapses with spike signal processing, learning, and memory functions. potential generates transient ionic fluxes in a polymer layer the gate, triggering an excitatory postsynaptic current drain. Temporally correlated pre- post-synaptic spikes modify ions stored polymer, resulting nonvolatile modification of spike-timing-dependent plasticity. Detailed facts importance specialist readers...

10.1002/adma.201000282 article EN Advanced Materials 2010-05-05

A carbon nanotube (CNT) synapse emulates a biological with its dynamic logic, learning, and memory functions induced by the interactions between CNTs hydrogen ions in an electrochemical cell. circuit of CNT synapses operates extremely low-energy consumption could potentially emulate neuronal network.

10.1002/adma.201203116 article EN Advanced Materials 2012-12-27

We report an analog neuromorphic module composed of p-type carbon nanotube (CNT) synapses and integrate-and-fire (I&F) circuit. The CNT synapse has a field-effect transistor structure with random network as its channel aluminum oxide dielectric layer implanted indium ions gate. A positive voltage pulse (spike) applied on the gate attracts electrons into defect sites layer, trapped are gradually released after is removed. modify hole concentration induce dynamic postsynaptic current in...

10.1021/nn401946s article EN ACS Nano 2013-06-27

Computers based on the Turing model execute artificial intelligence (AI) algorithms that are either programmed by humans or derived from machine learning. These AI cannot be modified during operation process according to environmental changes, resulting in significantly poorer adaptability new environments, longer learning latency, and higher power consumption compared human brain. In contrast, neurobiological circuits can function while simultaneously adapting changing conditions. Here, we...

10.1126/sciadv.adr2082 article EN cc-by-nc Science Advances 2025-02-28

Magnetic nanomaterials with multimodal functionalities have emerged as a versatile platform for biomedical applications that range from basic cellular interrogation to clinical nanomedicine. In this work, we prepared electrodeposited ferromagnetic nickel nanowires efficient internalization into 3T3 fibroblasts. Agitation of the by low external field induced cell death, assessed MTT viability assays. The response interleukin-6 (IL-6) gene expression fibroblasts nanowire-mediated manipulation...

10.1021/jp806187r article EN The Journal of Physical Chemistry C 2008-09-10

The fastest supercomputer, Summit, has a speed comparable to the human brain, but is much less energy-efficient (≈1010 FLOPS W-1 , floating point operations per second watt) than brain (≈1015 ). processes and learns from "big data" concurrently via trillions of synapses in parallel analog mode. By contrast, computers execute algorithms on physically separated logic memory transistors serial digital mode, which fundamentally restrains handling efficiently. existing electronic devices can...

10.1002/adma.201808032 article EN publisher-specific-oa Advanced Materials 2019-03-25

Neurobiological circuits containing synapses can process signals while learning concurrently in real time. Before an artificial neural network (ANN) execute a signal-processing program, it must first be programmed by humans or trained with respect to large and defined data set during processes, resulting significant latency, high power consumption, poor adaptability unpredictable changing environments. In this work, crossbar circuit of synaptic resistors (synstors) is reported, each synstor...

10.1002/adma.202210484 article EN Advanced Materials 2023-02-13

The optical switching properties of gadolinium–magnesium hydride have been demonstrated in a solid-state electrochromic device. With positive polarization the electrode, visible reflectance approaches 35% with virtually zero transmission, while negative polarization, transmission exceeds 25% at 650 nm. is reversible, intermediate between transparent and reflecting states.

10.1063/1.124853 article EN Applied Physics Letters 1999-09-27

We report an organic, nonvolatile memory based on dopant concentration-induced conductance changes in a conjugated polymer. Consisting of polymer poly [2-methoxy-5-(2′-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV)/ionic conductor (RbAg4I5) bilayer sandwiched between two metal electrodes, the device is electrically switched its low-conductance “off” state and high-conductance “on” reversibly repeatedly with on/off ratios above orders magnitude pulse durations as short 1μs when voltage...

10.1063/1.2191874 article EN Applied Physics Letters 2006-03-27

An organic bistable device with a structure Cu∕Cu2S/copperphthalocyanine (Cu-Pc)∕Pt was fabricated. Compared to the single layer composed of Cu∕Cu-Pc∕Pt, bilayer devices were observed show distinct bistability resistance ratio off/on states up 107 and low switch voltage (0.75–0.85V). At least 105 switching cycles achieved in “write-read-erase-read” cycle voltage. The filament mechanism for is supported by “metallic” behavior their temperature dependence on state. Such memory provides...

10.1063/1.2771064 article EN Applied Physics Letters 2007-08-13

Abstract A nonvolatile analog memory transistor is demonstrated by integrating C60 molecules as charge storage in the gate, and carbon nanotubes (CNTs) channel. The currents through CNT channel can be tuned quantitatively reversibly to values controlling number of electrons trapped molecules. After tuning, current channel, preserved a manner, indicating characteristics memory.

10.1002/smll.201202593 article EN Small 2013-02-06

The rational design of surfaces for immobilization proteins is essential to a variety biological and medical applications ranging from molecular diagnostics advanced platforms fundamental studies cell biology. We have developed an electrochemically based approach site-selective reaction-controlled on surfaces. When monolayer 4-nitrothiophenol gold electrode reduced in selective fashion at its nitro groups, afford amino groups by potentiometric scans, the amine can be employed orchestrate...

10.1021/bc7002296 article EN Bioconjugate Chemistry 2007-10-26

In the study described in this report orthogonal Click reactions were utilized to immobilize two different proteins on surfaces side-by-side and multilayer constructs. Alkyne- azide-functionalized poly(ethylene glycol) hydrogel features fabricated. Copper-catalyzed Huisgen 1,3 dipolar cycloaddition oxime chemistry employed conjugate an ubiquitin oxoamide-modified myoglobin, respectively. Multicomponent patterning was verified by fluorescence imaging.

10.1039/c1sm05991b article EN Soft Matter 2011-01-01

A doping‐modulated carbon nanotube (CNT) electronic device, called a “synapstor,” emulates the function of biological synapse. The CNT synapstor has field‐effect transistor structure with random network as its channel. An aluminium oxide (Al 2 O 3 ) film is deposited over half channel in synapstor, converting covered part from p‐type to n‐type, forming p–n junction and increasing Schottky barrier between n‐type metal contact. This scheme significantly improves postsynaptic current (PSC)...

10.1002/smll.201402528 article EN Small 2014-11-25

In this work, the effect of rapid thermal annealing (RTA) temperature on ferroelectric polarization in zirconium-doped hafnium oxide (HZO) was studied. To maximize remnant (2P r ), in-plane tensile stress induced by tungsten electrodes under optimal RTA temperatures. We observed an increase 2P with temperature, likely due to increased proportion polar phase HZO. The HZO capacitors annealed at 400°C did not exhibit any behavior, whereas 800°C became highly leaky and shorted for voltages above...

10.3389/fmats.2022.969188 article EN cc-by Frontiers in Materials 2022-08-25

Paint by number? Magnetic nanoparticles (MNPs) coated with distinct biomolecules (see picture) can be assembled onto nanoelectrodes on a template under the control of magnetic and electric fields. The MNP–biomolecule conjugates then transferred from to biocompatible polymer substrate. Arbitrary nanopatterns fabricated lithography process over large area resolution down 10 nm. Detailed facts importance specialist readers are published as ”Supporting Information”. Such documents peer-reviewed,...

10.1002/anie.200803456 article EN Angewandte Chemie International Edition 2008-11-12

Abstract Resistive random-access memory is a candidate for next-generation non-volatile architectures. In this study, we use flexographic roll-to-roll printing technology deposition of the resistive layer, method that allows fast and cost-effective fabrication to create devices. Metal-free organic polymers blends composed poly(methyl methacrylate) (PMMA) surplus poly(vinyl alcohol) (PVA) serve as active layer. Microscopic studies printed layers show circular domains PMMA embedded in PVA. The...

10.1007/s00339-021-04851-9 article EN cc-by Applied Physics A 2021-08-25
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