- Analytical Chemistry and Chromatography
- Analytical Methods in Pharmaceuticals
- Various Chemistry Research Topics
- Chromatography in Natural Products
- Microfluidic and Capillary Electrophoresis Applications
- Antibiotics Pharmacokinetics and Efficacy
- Pesticide Residue Analysis and Safety
- Analytical chemistry methods development
- Ionic liquids properties and applications
- Advanced Chemical Sensor Technologies
- Pharmacological Effects and Assays
- E-Learning and Knowledge Management
- Protein purification and stability
- History and advancements in chemistry
- Biochemical Analysis and Sensing Techniques
- Crystallization and Solubility Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Innovative Teaching Methods
- Problem and Project Based Learning
- Dye analysis and toxicity
- Chemistry and Chemical Engineering
- Insect and Pesticide Research
- Experimental Learning in Engineering
- Melamine detection and toxicity
- Analytical Chemistry and Sensors
Universitat Jaume I
2015-2025
Universitat de València
1997-2024
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
2023-2024
Hospital General Universitari de Castelló
2015
Ayuntamiento de Castellón de la Plana
2014
Université Claude Bernard Lyon 1
2003-2006
Centre National de la Recherche Scientifique
2003-2004
Iowa State University
2003
This review is the result of a survey across bibliography about determination several antibiotics in biological, food and environmental samples by liquid chromatography. Their those usually made clinical monitoring, safety studies. A brief description pharmacological activity provided, to complement relevance topic bioanalytical method. Exposure antimicrobial agents, which can be evaluated analysis biological fluids, comes mainly from their extensive use as veterinary agents industrial...
Countercurrent chromatography (CCC) is a liquid technique with stationary phase. Taking advantage of the nature phase, it possible to perform unique operations not in classical solid It easy avoid any solute-irreversible absorption CCC column. If retention volumes solutes become too high, dual mode will be used. The roles phases are reversed. phase becomes mobile and column started again. elute rapidly what was previously theoretical basis dual-mode method recalled. discontinuous method....
Abstract Salts with low melting points, also termed room‐temperature ionic liquids, can be used as matrices in matrix‐assisted laser desorption/ionization time‐of‐flight (MALDI‐TOF). They have great vacuum stability, and dissolve polar apolar solutes including carbohydrates, biological oligomers proteins. The liquids give much more homogeneous sample solutions compared solid matrices. We demonstrate the usefulness of using to determine molecular weight DNA by direct TOF mass spectrometric...
Countercurrent chromatography was used to determine the octanol−water partition coefficients (Po/w) of 23 diuretic drugs. The measured Po/w values ranged over 4 orders magnitude from 0.05 550 (−1.3 < log +2.7). All compounds, except spironolactone, were ionizable. strongly depending on aqueous-phase pH. A theoretical model linking these with pH derived for four cases: (i) molecular acid−anionic base, (ii) cationic acid−molecular (iii) biprotic systems two acidic or basic groups showing same...
ABSTRACT We developed a practical and economic method based on micellar liquid chromatography for the quantification of atomoxetine methylphenidate, two central nervous system stimulants used to treat attention deficit hyperactivity disorder, in solid dosage forms. Samples were solved mobile phase directly injected, after filtration. Both drugs resolved from matrix compounds using carbon‐18 column consisting solution 0.10 mol/L sodium dodecyl sulfate—6% 1‐pentanol, phosphate‐buffered pH 7,...