Tingting Lan

ORCID: 0000-0002-4865-4092
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About
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Research Areas
  • Orthodontics and Dentofacial Orthopedics
  • Temporomandibular Joint Disorders
  • Tissue Engineering and Regenerative Medicine
  • Mesenchymal stem cell research
  • Electrospun Nanofibers in Biomedical Applications
  • Periodontal Regeneration and Treatments
  • Cardiac Ischemia and Reperfusion
  • Electrochemical sensors and biosensors
  • Dental Implant Techniques and Outcomes
  • 3D Printing in Biomedical Research
  • Analytical Chemistry and Sensors
  • Organ Transplantation Techniques and Outcomes
  • Liver physiology and pathology
  • Apelin-related biomedical research
  • Plant Molecular Biology Research
  • Proteoglycans and glycosaminoglycans research
  • Surgical Sutures and Adhesives
  • Endodontics and Root Canal Treatments
  • Hepatitis C virus research
  • Medical Research and Treatments
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Advanced Wireless Communication Techniques
  • dental development and anomalies
  • Renin-Angiotensin System Studies
  • Oropharyngeal Anatomy and Pathologies

Tianjin First Center Hospital
2023-2024

Tianjin Medical University
2023-2024

Nankai University
2022-2024

Sichuan University
2017-2023

State Key Laboratory of Oral Diseases
2017-2023

Central South University
2023

Hebei Medical University
2022

Second Hospital of Hebei Medical University
2022

Deyang Stomatological Hospital
2022

Zhangzhou Municipal Hospital of Fujian Province
2020

Abstract Mounting casts accurately on an articulator is a prerequisite for the treatment planning/execution of complex dental cases that require occlusal rehabilitation. A full digital approach to transfer position maxillary dentition virtual articulator, by using intraoral scans and cone beam computed tomography (CBCT) files presented. This technique offers reduced chairside time flexibility choosing orientation plane. It can be used in orthognathic surgeries, interdisciplinary treatments...

10.1111/jopr.13023 article EN Journal of Prosthodontics 2019-01-21

Abstract Xenogenic organ transplantation has been considered the most promising strategy in providing possible substitutes with physiological function of failing organs as well solving problem insufficient donor sources. However, xenograft, suffered from immune rejection and ischemia-reperfusion injury (IRI), causes massive reactive oxygen species (ROS) expression subsequent cell apoptosis, leading to xenograft failure. Our previous study found a positive role PPAR-γ anti-inflammation...

10.1038/s41368-023-00217-4 article EN cc-by International Journal of Oral Science 2023-02-16

Continuous in vivo monitoring (CIVM) of pH value is essential for personalized medicine, as many diseases are closely related to acid-base imbalances. However, conventional meters limited their ability perform CIVM due excessive blood consumption, large device volume, frequent calibration, and inadequate real-time monitoring. There thus an urgent need a portable method value. To address this need, we propose minimally invasive, continuous solution the form implantable microneedle sensor...

10.3390/polym15132796 article EN Polymers 2023-06-23

Rapid, low-cost and high-specific diagnosis based on nucleic acid detection is pivotal in both detecting controlling various infectious diseases, effectively curbing their spread. Moreover, the analysis of circulating DNA whole blood has emerged as a promising noninvasive strategy for cancer monitoring. Although traditional methods are reliable, time-consuming intricate processes restrict application rapid field assays. Consequently, an urgent emphasis point-of-care testing (POCT) acids...

10.1080/10408347.2024.2366943 article EN Critical Reviews in Analytical Chemistry 2024-06-18

Abstract Periodontitis is a destructive and chronic inflammatory disease initiated sustained by multiple proinflammatory mediators. Current therapies mainly deal with bacteria elimination, but directly addressing the over‐accumulated mediators in periodontal microenvironment still remains substantial challenge for regenerative periodontitis treatment. Herein, inspired blood coagulation, an off‐the‐shelf artificial clot hydrogel encapsulated platelet‐rich plasma (PRP) reported to mitigate...

10.1002/advs.202504106 article EN cc-by Advanced Science 2025-05-28

The low survival rate or dysfunction of extracellular matrix (ECM)-based engineered organs caused by the adverse effects unfavourable local microenvironments on seed cell viability and stemness, especially excessive reactive oxygen species (ROS), prompted us to examine importance controlling oxidative damage for tissue transplantation regeneration. We sought improve tolerance cells transplant microenvironment via antioxidant pathways, thus promoting efficiency achieving better improved...

10.1186/s13287-021-02237-5 article EN cc-by Stem Cell Research & Therapy 2021-03-22

Recent advances in 3D printing offer a prospective avenue for producing transplantable human tissues with complex geometries; however, the appropriate 3D-printed scaffolds possessing biological compatibility tooth regeneration remain unidentified. This study proposes personalized scaffold of multiple bioactivities, including induction stem cell proliferation and differentiation, biomimetic mineralization, angiogenesis. A brand-new bioink system comprising biocompatible biodegradable polymer...

10.1002/adhm.202300625 article EN Advanced Healthcare Materials 2023-07-31

To detect parameters associated with the craniomaxillofacial system that could be altered during hyperdivergent skeletal class II malocclusion camouflage treatment for better profile improvement.Forty-two subjects who had finished their orthodontic treatments and achieved good soft tissue responses were included in this study. Cephalometric analyses of these patients taken before (T1) after (T2) treatment. Measurements made at each stage analyzed within between groups.No obvious decrease...

10.21037/atm-22-135 article EN Annals of Translational Medicine 2022-02-01

Abstract Background The effectiveness of anterior crossbite treatment in preschool-aged children depends on the design and patient compliance. Common early appliances with steel wires acrylic resin can bring about numerous problems, such as toothache, sore gums mucous membrane injury. aim this study was to propose a new clear removable appliance provide preschool-age an improved experience occlusal interference treatment. Methods Appliances were designed help 3-dimensional (3D) digital...

10.1186/s12903-021-01393-7 article EN cc-by BMC Oral Health 2021-01-21

With the kinematic face bow, condyle movements representing temporomandibular joint function can be recorded instantly. The condylography curves utilized for diagnostic analysis, as different pathophysiological conditions have unique curve patterns. By tracing specific alterations on curves, structural and functional statuses of predicted. However, to best our knowledge, no standardized practicable evaluation protocol jaw movement exists. In current study, features either normal or abnormal...

10.7518/hxkq.2017.05.021 article EN PubMed 2017-10-01

Diabetes and periodontitis develop influence each other. The peroxisome proliferator-activated receptor gamma (PPARγ) agonist rosiglitazone (RSG) controls blood glucose hence the systemic diseases associated with diabetes by increasing sensitivity of tissues to insulin. However, whether how RSG can treat diabetic is poorly understood.Insulin-resistant periodontal ligament stem cells (IR-PDLSCs) were induced glucosamine (18 mM, 24 h) in presence or absence GW9662 (a PPARγ antagonist). uptake...

10.21037/atm-22-2207 article EN Annals of Translational Medicine 2022-05-01

Abstract Pump is a vital component for expelling the perfusate in small animal isolated organ normothermic machine perfusion (NMP) systems whose flexible structure and rhythmic contraction play crucial role maintaining system homeostasis. However, continuous extrusion forming with rigid stationary shaft of peristaltic pumps can damage cells, leading to metabolic disorders eventual dysfunction transplanted organs. Here, we developed novel biomimetic blood‐gas (BBGs) preventing cell damage....

10.1002/btm2.10724 article EN cc-by Bioengineering & Translational Medicine 2024-09-23
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