A5032704832- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Pulmonary Hypertension Research and Treatments
- Health and Conflict Studies
- Cardiac pacing and defibrillation studies
- Maternal and fetal healthcare
- Acute Myocardial Infarction Research
- Takotsubo Cardiomyopathy and Associated Phenomena
- Ion channel regulation and function
- Cardiac Imaging and Diagnostics
- Reproductive Health and Contraception
- Sepsis Diagnosis and Treatment
- Aortic Disease and Treatment Approaches
- Congenital heart defects research
- Cardiac electrophysiology and arrhythmias
- Pregnancy and preeclampsia studies
- Mitochondrial Function and Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Cardiac Valve Diseases and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Coronary Artery Anomalies
- Emergency and Acute Care Studies
Erasmus MC
2017-2021
Institute of Cardiology
2021
Albert Schweitzer Ziekenhuis
2016-2021
Erasmus University Rotterdam
2018-2020
McGill University
2020
Université Claude Bernard Lyon 1
2020
Maria Cecilia Hospital
2020
Ghent University Hospital
2020
European Society of Cardiology
2020
University of East Anglia
2019
Abstract Aims Reducing maternal mortality is a World Health Organization (WHO) global health goal. Although deaths due to haemorrhage and infection are declining, those related heart disease increasing now the most important cause in western countries. The aim define contemporary diagnosis-specific outcomes pregnant women with disease. Methods results From 2007 2018, were prospectively enrolled Registry Of Pregnancy And Cardiac (ROPAC). Primary outcome was or failure, secondary other...
Background Cardiovascular disease is the leading cause of death during pregnancy with thoracic aortic dissection being one main causes. Thoracic commonly related to hereditary disorders and congenital heart malformations such as bicuspid valve (BAV). Pregnancy considered a high risk period in women underlying aortopathy. Methods The ESC EORP Registry Of And Cardiac (ROPAC) prospective global registry that enrolled 5739 pre-existing cardiac disease. With this analysis, we aim study maternal...
Background The prevalence of ischemic heart disease (IHD) in women child‐bearing age is rising. Data on pregnancies however are scarce. objective to describe the pregnancy outcomes these women. Methods and Results European Society Cardiology‐EURObservational Research Programme ROPAC (Registry Pregnancy Cardiac Disease) a prospective registry which data with were collected from 138 centers 53 countries. Pregnant preexistent pregnancy‐onset IHD included. Primary end point maternal cardiac...
Cardiac disease is a major cause of maternal mortality. Data regarding pregnancy outcomes in women with systemic right ventricle (sRV) are scarce. We studied an sRV after the atrial switch procedure for transposition great arteries (TGA) or congenitally corrected TGA (CCTGA).
(Abstracted from Eur Heart J 2019;40:3848–3855) The World Health Organization recognizes that the reduction of maternal mortality worldwide is a critical goal. Currently, 1% to 4% pregnant women have heart disease, which has translated into 15% deaths.
Objective Pregnancy in women with aortic coarctation (CoA) has an estimated moderately increased risk (mWHO II–III) of adverse cardiovascular, obstetric or fetal events, but prospective data to validate this classification are scarce. We examined pregnancy outcomes and identified associations outcomes. Methods Pregnancies CoA were selected from the worldwide Registry Cardiac Disease (ROPAC, n=303 out 5739), part European Society Cardiology EURObservational Research Programme. The frequency...
Background In the past 3 decades, arterial switch procedure has replaced atrial as treatment of choice for transposition great arteries. Although survival is superior after procedure, data on pregnancy outcomes are scarce and arteries not yet included in modified World Health Organization classification maternal cardiovascular risk. Methods Results The ROPAC (Registry Pregnancy Cardiac disease) an international prospective registry pregnant women with cardiac disease, part European Society...
Objective In existing risk stratification and resuscitation guidelines for sepsis, a hypotension threshold of systolic blood pressure (SBP) below 90–100 mmHg is typically used. However, older patients, the clinical relevance SBP in seemingly ‘normal’ range (>100 mmHg) still poorly understood, as they may need higher adequate tissue perfusion due to arterial stiffening. We therefore investigated association between mortality emergency department (ED) patients hospitalised with suspected...
Pregnant women with mechanical heart valves are at significant risk of obstetric/cardiac complications. This study compares the anticoagulation management in two obstetric cardiac centres.Retrospective case-note review from Chelsea and Westminster/Royal Brompton Hospitals (CR) Erasmus Medical Centre (EMC). Main outcome measure was valve thrombosis.Nineteen pregnancies CR 25 EMC were included. Most on low-molecular-weight heparin (LMWH) throughout pregnancy CR, whereas most had LMWH first...
Tetralogy of Fallot (TOF) is the commonest cyanotic congenital heart defect. When surgically repaired at young age over 90% patients reach adult and most women have a desire to become pregnant However, pregnancy associated with up 50% increase in cardiac output also an elevated risk arrhythmias thrombosis. The aim this study was describe outcomes TOF for both mother baby assess influence on right ventricular (RV) dimensions. Within prospective, international ESC EORP Registry Of Pregnancy...
Congenital long-QT (LQT) syndrome can lead to torsades de pointes (TdP), which deteriorate into ventricular fibrillation resulting in sudden death. Thus far, more than 16 genes have been linked the LQT syndrome. We report an orgasm-induced TdP a patient with type 2 novel mutation KCNH2 gene. A 24-year-old Caucasian woman medical history of depression, no medication use and family death, presented recurrent syncope during sexual activity. Immediately after achieving orgasm intercourse she...
1272 Best Posters in congenital heart diseases / hypertension basic research monitored by weekly anti-Xa levels during the first trimester.In second arm (n=17), warfarin dose was decreased to 2.5 mg/day trimester and combined with enoxaparine given a similar manner.In third 4 used trimester.Full continued after all arms.If patient's therapeutic less than 5 mg before pregnancy, alone same throughout entire pregnancy 4th observational (n=9).All patients were followed serial transesophageal...
Abstract Background Cardiac disease is one of the major causes maternal mortality. We studied pregnancy outcomes in women with a systemic right ventricle (sRV) after atrial switch procedure for transposition great arteries (TGA) or congenitally corrected TGA (CCTGA). Methods The ESC-EORP Registry Pregnancy and Disease an international prospective registry pregnant cardiac disease. (maternal fetal) sRV are described. primary endpoint was cardiovascular event (MACE) defined as death,...