Rada M. Grubovic Rastvorceva

ORCID: 0000-0002-4885-3323
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Research Areas
  • Hematopoietic Stem Cell Transplantation
  • Blood donation and transfusion practices
  • Mesenchymal stem cell research
  • COVID-19 Clinical Research Studies
  • Erythrocyte Function and Pathophysiology
  • Hemoglobinopathies and Related Disorders
  • Acute Myeloid Leukemia Research
  • SARS-CoV-2 and COVID-19 Research
  • Blood groups and transfusion
  • Blood transfusion and management
  • Venous Thromboembolism Diagnosis and Management
  • Neutropenia and Cancer Infections
  • Hematological disorders and diagnostics
  • Prostate Cancer Treatment and Research
  • Cancer Research and Treatments
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Cancer Treatment and Pharmacology
  • Multiple Sclerosis Research Studies
  • Monoclonal and Polyclonal Antibodies Research
  • Dietary Effects on Health
  • Immunodeficiency and Autoimmune Disorders
  • Tissue Engineering and Regenerative Medicine
  • Pregnancy and preeclampsia studies
  • Systemic Sclerosis and Related Diseases
  • Organ Donation and Transplantation

Institute of public health of Republic of Macedonia
2019-2024

Goce Delcev University
2021-2024

Sportska Akademija Beograd
2023

Serbian Academy of Sciences and Arts
2023

Saints Cyril and Methodius University of Skopje
2017-2022

Institute for Transfusion Medicine
2014-2021

Croatian Institute of Transfusion Medicine
2014-2021

UCLA Health
2011

Enabling universal access to safe blood components should be a key component of every country's national healthcare strategy. This study aimed assess the current status infrastructure and resources transfusion services (BTS) in low- middle-income countries.A cross-sectional survey was designed gather information on donations, components, redistribution, testing quality management systems (QMSs). The distributed International Society Blood Transfusion members between October 2021 November...

10.1111/vox.13373 article EN Vox Sanguinis 2022-11-08

BACKGROUND: Successful hematopoietic stem cell transplantation (HSCT) requires a rapid and durable recovery.AIM: The aim of our study was to analyse factors that influence recovery after autologous HSCT.MATERIALS AND METHODS: Multiple regression analysis used affecting neutrophil platelet engraftment in 90 transplanted patients – 30 with acute myeloid leukaemia (AML), lymphoma multiple myeloma (MM) from 2008 till 2016.RESULTS: AML significantly influenced by transfusion support...

10.3889/oamjms.2017.039 article EN Open Access Macedonian Journal of Medical Sciences 2017-06-03

Background: The frequency of ABO, Rh and Kell blood group antigens differs among populations different ethnic ancestry. There are low-frequency (<1%) high-frequency (>90%). A rare is defined as the absence a antigen in general population, well multiple frequent within single or systems. Aim: To perform red cell typing to calculate phenotype frequencies, order identify donors clinically most important АВО, Material Methods: (D, C, E, c, e) (K) was performed using specific monoclonal sera...

10.2478/prilozi-2022-0021 article EN PRILOZI 2022-07-01

Abstract Artificial intelligence (AI) uses sophisticated algorithms to “learn” from large volumes of data. This could be used optimise recruitment blood donors through predictive modelling future supply, based on previous donation and transfusion demand. We sought assess utilisation AI establishments (BE) conducted illustrate its use. A BE survey data was disseminated the International Society Blood members. Additional anonymzed were obtained Italy, Singapore United States (US) build models...

10.1111/tme.13071 article EN Transfusion Medicine 2024-08-08

Abstract Background and Objectives The use of coronavirus disease 2019 (COVID‐19) convalescent plasma (CCP) in the treatment patients with severe acute respiratory syndrome‐2 infection has been controversial. Early administration CCP before hospital admission offers a potential advantage. This manuscript summarizes current trials early explores feasibility this approach different countries. Materials Methods A questionnaire was distributed to International Society Blood Transfusion (ISBT)...

10.1111/vox.13347 article EN Vox Sanguinis 2022-09-14

&#x0D; BACKGROUND: Allogeneic stem cell transplantation (ASCT) is a potentially curative therapeutic approach in patients with intermediate and high-risk myelodysplastic syndrome (MDS). If family sibling or unrelated donor not available mismatched donors are viable option for young no comorbidities. The aim of this case presentation was to evaluate our first experience haploidentical indication.&#x0D; CASE PRESENTATION: We present 50 years male patient (MDS) diagnosed at University Clinic...

10.3889/oamjms.2021.7542 article EN Open Access Macedonian Journal of Medical Sciences 2021-11-23

BACKGROUND: Peripheral blood hematopoietic stem cells (PBSC) have largely replaced bone marrow derived in autologous transplantations, and become the preferred source of majority allogeneic transplantations. Sufficient number mobilized collected (HSC) is needed for successful cell transplantation.MATERIAL AND METHOD: This study was performed Institute Transfusion Medicine RM University Clinic Hematology from 2008 till 2016. There were 30 90 donors that underwent mobilization collection PBSC....

10.3889/seejim.2017.20012 article EN South East European Journal of Immunology 2017-12-26

Inherited fibrinogen disorders introduce risk for recurrent abortions, sub-chorionic haematoma, placental abruption and postpartum haemorrhage. This is a case report of successful pregnancy outcome in 37-year old woman with hypofibrinogenaemia. She was referred to coagulation test the first trimester because history preeclampsia HELLP syndrome previous pregnancy. Hypofibrinogenaemia diagnosed level 0.7 g/L. During she regularly monitored levels multiple cryoprecipitate concentrates were...

10.5937/scriptamed51-26499 article EN cc-by SCRIPTA MEDICA 2020-01-01

Background: COVID-19 convalescent plasma (CCP) is an important antiviral option for selected patients with COVID-19. Materials and Methods: In this open-label, phase 2, clinical trial conducted from 30 April 2020 till 10 May 2021 in the Republic of North Macedonia, we evaluated efficacy safety CCP hospitalized patients. Treatment was a single unit having anti-RBD IgG concentration higher than 5 AU/mL. Results: There were 189 that completed study, which 65 (34.4%) had WHO 8-point progression...

10.3390/life12101565 article EN cc-by Life 2022-10-09

The Safety of the Blood Supply in any country is utmost importance to safeguard patients from serious adverse events blood transfusion. Implementation a Quality System Transfusion Service, with support Government and Ministry Health key element guarantee safe blood. IPA TAIB 2009 project - Strengthening executed 2013/14 provided the means start implementing Institute for Medicine Republic Macedonia. This aimed ultimately bring Service European Union standards, allowing exchange components...

10.3889/oamjms.2014.091 article EN Open Access Macedonian Journal of Medical Sciences 2014-09-15

There are many factors for in vitro fertilization (IVF) failure, and hereditary thrombophilia has been mentioned as one of them the last few years. Thrombophilia is a condition predisposition to thromboembolism. The aim study was evaluate sociodemographic characteristics examine representation thrombophilic mutations women with IVF failure. Material methods: In retrospective-prospective case-control we evaluated 52 women, divided two groups. Twenty-twowomen at least three failures were...

10.3889/aph.2019.4195 article EN cc-by-nc Archives of Public Health 2019-08-22
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