A5063259879- Hemoglobinopathies and Related Disorders
- Blood donation and transfusion practices
- Blood groups and transfusion
- COVID-19 Clinical Research Studies
- Blood transfusion and management
- Iron Metabolism and Disorders
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- SARS-CoV-2 and COVID-19 Research
- Neonatal Health and Biochemistry
- COVID-19 Impact on Reproduction
- Erythrocyte Function and Pathophysiology
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Complement system in diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Acute Myeloid Leukemia Research
- Blood disorders and treatments
- Long-Term Effects of COVID-19
- Viral Infections and Outbreaks Research
- Organ Donation and Transplantation
- Pregnancy and preeclampsia studies
- Hematological disorders and diagnostics
- Trauma and Emergency Care Studies
- COVID-19 diagnosis using AI
- COVID-19 and healthcare impacts
- Vector-borne infectious diseases
King Abdulaziz University
2015-2024
Health Affairs
2024
Directorate of Health
2024
King Fahd Medical City
2024
King Abdulaziz Hospital
2020-2023
University Research Co (United States)
2023
All India Institute of Medical Sciences
2021
World Health Organization Regional Office for South-East Asia
2021
Wuhan Blood Center
2021
Shaanxi Blood Center
2021
The coronavirus disease 2019 (COVID-19) pandemic has impacted blood systems worldwide. Challenges included maintaining supplies and initiating the collection use of COVID-19 convalescent plasma (CCP). Sharing information on challenges can help improve utilization.A survey questionnaire was distributed to International Society Blood Transfusion members in 95 countries. We recorded respondents' demographic information, impacts supply, CCP use, transfusion demands operational...
Iron chelation therapy is often used to treat iron overload in patients requiring transfusion of red blood cells (RBC). A 76-year-old man with MDS type refractory cytopenia multilineage dysplasia, intermediate-1 IPSS risk, was referred when he became dependent. He declined infusional but subsequently accepted oral therapy. Following the initiation chelation, RBC requirement ceased and remained independent over 40 months later. Over same time course, ferritin levels decreased did not...
Abstract Many patients with primary myelofibrosis (PMF) become red blood cell (RBC) transfusion dependent (TD), risking iron overload (IOL). Iron chelation therapy (ICT) may decrease the risk of haemosiderosis associated organ dysfunction, though its benefit in PMF is undefined. To assess effect TD and ICT on survival PMF, we retrospectively reviewed 41 patients. Clinical data were collected from database by chart review. The median age at diagnosis was 64 (range 43–86) years. Median white...
Abstract Background Novel SARS‐CoV‐2 (COVID‐19) virus has rapidly spread worldwide and was declared a pandemic, making identifying prioritizing individuals most at risk critical challenge. The literature describes an association between blood groups the susceptibility to various viral infections their severity. Knowing if specific group more COVID‐19 may help improve understanding pathogenesis severity of disease. We aimed assess ABO/RhD severity, compare results with similar studies in...
BACKGROUND Blood transfusion is the first‐line treatment for patients with thalassemia and many sickle cell patients. However, cases of unregulated blood are shown to carry a high risk alloimmunization red cells (RBCs), which can lead hemolytic reaction be fatal Screening identification alloantibodies are, therefore, essential practice in services. Transfusion phenotyped minimize these risks STUDY DESIGN AND METHODS A prospective study was carried out on 1015 donors, retrospective 208...
In response to the coronavirus disease 2019 (COVID-19), Saudi Arabia have imposed timely restrictions minimize infection spread, lower risk for vulnerable groups, and reduce pressure on healthcare services. The effectiveness of these measures has not been assessed comprehensively and, thereby, remains uncertain. Besides monitoring number COVID-19 cases diagnosed by molecular assays, seroprevalence can serve as an indicator incidence rate among general population. This study aimed evaluate...
Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome (SARS-CoV-2), is associated with significant morbidity and mortality. The clinical features of COVID-19 were mentioned in previous studies. However, risk factors for are not fully recognized. aim this study to characterize Jeddah, Saudi Arabia. A retrospective, chart-review, case-control was conducted at King Abdulaziz University, Demographic, clinical, radiological, laboratory data on patients diagnosed between...
Background: Therapeutic plasma exchange (TPE) is a procedure involving the filtration of patient's to eliminate pathogenic components or address deficiencies. This technique finds varied indications in pediatric age group, particularly neuroinflammatory diseases. Objectives: The objective this study delve into our local experience with TPE, focusing on indications, outcomes, and complications among children neurological diseases at King Abdulaziz University Hospital (KAUH) Jeddah, Saudi...
Abstract Iron deficiency (ID) and iron anemia (IDA) are extremely common in females Saudi Arabia highly prevalent pregnancy. The MOH Mother Health Passport recommends that pregnant women undergo testing for complete blood count ferritin every trimester. purpose of this study was to describe practices screening ID or IDA during pregnancy identify the prevalence IDA. inclusion criteria were all patients who had at least 2 antenatal visits same center 336 included. It noted 591 (51.5%)...
To report 2-years experience of using transfusion-related quality indicators as a tool in hemovigilance system implementation. The study was carried out between 2012 and 2013. Blood transfusion service data were prospectively collected at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Donor reactions, fresh frozen plasma (FFP) in-date wastage, incidents, errors pertaining to orders, or requests quarterly forwarded the Hospital Transfusion Committee (HTC) for review. population...
Screening all blood donors for human T-cell lymphotropic viruses 1 and 2 (HTLV HTLV 2) is mandatory in Saudi Arabia. The aim of this study to evaluate the results costs associated with current testing policy at King Abdulaziz University Hospital (KAUH), Jeddah.Donor-testing from Blood Transfusion Services KAUH were reviewed over a 10-year period, January 2006 through December 2015. All screened using chemiluminescent microparticle immunoassay. Reactive samples then tested by Western blot...
Plasmapheresis and IVIG use in cases of alloimmunization during pregnancy are effective strategies when severe early fetal anemia is anticipated. Despite no change antibody titer levels before after plasmapheresis, clinical response was observed both fetuses, had an excellent obstetrical outcome.
The coronavirus disease 2019 (COVID-19) pandemic is challenging healthcare systems worldwide. prediction of prognosis has a critical role in confronting the burden COVID-19. We aimed to investigate feasibility predicting COVID-19 patient outcomes and severity based on clinical hematological parameters using machine learning techniques. This multicenter retrospective study analyzed records 485 patients with COVID-19, including demographic information, symptoms, variables, treatment outcomes....
Background: Since the beginning of COVID-19 pandemic, many associated factors have been investigated to clarify susceptibility and severity among affected individuals. Biological markers can play an important role in identification individual such pandemic. Growing evidence suggest influence different blood group systems on virus, with a particular type conferring selection advantage.
 Objectives: The study aimed determine association ABO, Rhesus (D) P1 groups Taif city, Western Saudi...
Around the world, millions of blood donations are collected annually. Whereas most from countries with a high or medium development index (HDI MDI respectively) processed into components, this may not yet be case in low (LDI) where transfusions whole common. As all therapeutic interventions, should only prescribed when clinically indicated. Careful consideration expected benefits and potential risks take place before every transfusion order. Although save many lives, they conversely...
Abstract Background Hemolytic disease of the fetus and newborn (HDFN) is a challenging condition that may necessitate need for intrauterine or neonatal transfusion. The ability to provide compatible blood depends on antibody identification antigen prevalence. We describe case was affected by HDFN secondary high‐prevalence unknown specificity. Study Design Methods A 29‐year‐old mother underwent emergency cesarean section fetal distress. had severe anemia hyperbilirubinemia. Antibody screening...
Background and Objective Sickle cell disease ( SCD ) is a chronic associated with myriad of complications including pain vaso‐occlusive manifestations. Transfusion the mainstay management ‐related complications. However, side‐effects alloimmunisation may develop affect outcomes. Marked phenotypic heterogeneity blood donors recipients increases risk alloimmunisation. We report on prevalence clinical among patients in Jeddah, Saudi Arabia. Materials Methods Medical records were reviewed for...
Background. The coronavirus disease-19 (COVID-19) pandemic caused a major impact on blood donation process and supply globally. A lockdown management procedure was launched nationally in Saudi Arabia to manage this global health crisis. main aim of study determine the effect COVID-19 services different regions Arabia. Study Design Methods. retrospective cross-sectional conducted bank centers 5 cities including Riyadh, Jeddah, Dammam, Hail, Jizan Demographic characteristics were retrieved...
BACKGROUND Turbidity tests are commonly used for screening blood units the presence of sickle cell trait (SCT) before transfusion to specific patient populations, based on recommendations AABB. In this pilot study, we evaluate a new method donors and hemoglobin. STUDY DESIGN AND METHODS This study was at King Abdulaziz University Hospital in Jeddah, Saudi Arabia. Study participants were approached consecutively between July 24, 2016, August 8, 2016. Blood donors, control individuals, known...
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory coronavirus 2(SARS-CoV-2), has rapidly spread since its first declaration the World Health Organization (WHO) as a global pandemic in March 2020 [1]. Until vaccination started to be rolled out an increasing number of countries, different modalities treatment were deployed attempt combat this deadly virus but with limited efficacy so far [2]. Collection and use convalescent plasma for (COVID-19) (CCP) passive...
In the absence of specialized care centers for hemoglobinopathies in Saudi Arabia, there are insufficient data on prevalence clinical complications this population. This is a retrospective record review about associated with at King Abdulaziz University Hospital, patients followed between January 1st 2010 through June 30th 2016. A total 349 were included, mean age 25.45 years, including 266 sickle cell disease and 80 thalassemia. Of those receiving regular transfusions, 17.5% developed...