A5012587617- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Antibiotic Use and Resistance
- Travel-related health issues
- COVID-19 Impact on Reproduction
- Virus-based gene therapy research
- Plant Virus Research Studies
- Pediatric health and respiratory diseases
- Hepatitis C virus research
- Vaccine Coverage and Hesitancy
- interferon and immune responses
- Urinary Tract Infections Management
- Hepatitis B Virus Studies
- Ubiquitin and proteasome pathways
- CAR-T cell therapy research
- Plant Pathogenic Bacteria Studies
- Antibiotic Resistance in Bacteria
- Plant-Microbe Interactions and Immunity
- Global Maternal and Child Health
- Genomics and Rare Diseases
- Protein Structure and Dynamics
- Animal Virus Infections Studies
- Adolescent Sexual and Reproductive Health
- Transgenic Plants and Applications
Umm al-Qura University
2021-2025
King Abdulaziz University
2022-2023
Jazan University
2020
University of Birmingham
2019
Due to the adverse effects of obesity on host immunity, this study investigated effectiveness COVID-19 vaccines (BNT162b2, ChAdOx-nCov-2019, and mRNA-1273) in inducing anti-SARS-CoV-2 Spike (S) neutralizing antibodies among individuals with various classes (class I, II, III, super obesity). Sera from vaccinated obese (n = 73) normal BMI controls 46) were subjected S-based enzyme-linked immunosorbent assay (ELISA) serum-neutralization test (SNT) determine prevalence titer antibodies....
Acinetobacter baumannii is pathogen of global concern. It causes infection, especially among immunocompromised individuals in intensive care units, due to its ability survive for long periods on hard surfaces and under a wide range environmental conditions become resistant almost all the available antibiotics used clinical practice. Objectives: This study aims address gap A. surveillance Saudi Arabia by tracking prevalence, patterns, trends acquired resistance at healthcare facility western...
This study was aimed at determining the prevalence estimate and association of transfusion-transmitted infections (TTIs) with ABO Rh blood groups among donors King Faisal Specialist Hospital Research Center (KFSH & RC) in western region Saudi Arabia. A retrospective conducted bank center KFSH RC from 1 January 2013 to 31 December 2019. Data on group testing, serological molecular investigations, assays, nucleic acid testing (NATs), socio-demographic information were gathered. During period,...
Introduction The human immunodeficiency virus (HIV) and acquired syndrome (HIV/AIDS) are worldwide public health issues. Since Saudi Arabia is growing more accessible to the outside world, it critical analyze general population's knowledge of HIV/AIDS transmission modes attitudes toward infected people, level awareness. Therefore, this study aimed assess as well awareness among population in Kingdom Arabia. Methods current online community-based cross-sectional descriptive was conducted...
The number of reports menstrual changes after COVID-19 vaccination in the Saudi population is still unknown. Therefore, this study aimed to assess effect vaccine(Pfizer, AstraZeneca, and Moderna) on cycle among females Arabia.
Antimicrobial stewardship programs (ASPs) are collaborative efforts to optimize antimicrobial use in healthcare institutions through evidence-based quality improvement strategies. The general administration of pharmaceutical care the Saudi ministry health (MOH) is putting outstanding implementing settings. Several surveys have been conducted globally and reported many types strategies their effectiveness. This study aims identify ASPs Makkah region hospitals perceived level success. We...
Cucumber mosaic virus (CMV, Bromoviridae: Cucummovirus), one of the most widespread plant viruses with several hosts, causes huge losses in yield quality and quantity. The occurrence various CMV strains high genetic diversity within complicate its management. We describe population structure Nigeria using partial RNA1 RNA3 gene sequences from three natural hosts: pepper (Capsicum annuum), tomato (Solanum lycopersicum), watermelon (Citrullus lanatus). One hundred six leaf samples were...
In response to the coronavirus disease 2019 (COVID-19), Saudi Arabia have imposed timely restrictions minimize infection spread, lower risk for vulnerable groups, and reduce pressure on healthcare services. The effectiveness of these measures has not been assessed comprehensively and, thereby, remains uncertain. Besides monitoring number COVID-19 cases diagnosed by molecular assays, seroprevalence can serve as an indicator incidence rate among general population. This study aimed evaluate...
The wild-type SARS-CoV-2 has continuously evolved into several variants with increased transmissibility and virulence. Delta variant which was initially identified in India created a devastating impact throughout the country during second wave. While efficacy of existing vaccines against latest remains unclear, extensive research is being carried out to develop potential antiviral drugs through approaches like silico screening drug-repurposing. This study aimed conduct docking-based virtual...
The risk of transmission viral respiratory tract infections (RTIs) is high in mass gatherings including Hajj. This cohort study estimated the incidence symptomatic RTIs and hand hygiene compliance with its impact among Hajj pilgrims during COVID-19 pandemic.During week rituals 2021, domestic were recruited by phone asked to complete a baseline questionnaire. Pilgrims followed up after seven days using questionnaire about development symptoms, practices hygiene. Syndromic definitions used...
Iron is a crucial micronutrient for immunity induction in response to infections and vaccinations. This study aimed investigate the effect of iron deficiency on COVID-19-vaccine-induced humoral immunity. We investigated effectiveness COVID-19 vaccines (BNT162b2, mRNA-1273, ChAdOx nCov-2019) iron-deficient individuals (n = 63) provide side-by-side comparison healthy controls 67). The presence anti-SARS-CoV-2 spike (S) anti-nucleocapsid (NP) IgG were assessed using in-house S- NP-based ELISA...
Viruses have evolved to inhibit cellular DNA damage response pathways that possess antiviral activities and utilize proviral activities. Adenovirus has evolved, primarily, by engaging with the ubiquitin-proteasome system promoting degradation of key proteins. differentially regulates ATR signaling during infection. The adenovirus E1B-55K binding protein E1B-AP5 participates in activated infection, while 12 E4orf6 negates Chk1 activation proteasome-dependent activator TOPBP1. studies detailed...
Emerging global infections, such as coronavirus disease (COVID-19), pose serious public health threats, especially for vulnerable groups, including pregnant women. Knowledge about the disease, attitudes toward prevention, and preventative practices can help curb spread of limit mortality well. To determine knowledge, attitudes, (KAP) among a cohort Saudi women who were either during pandemic or at time data collection. A cr
Environmental conditions in hospitals facilitate the growth and spread of pathogenic bacteria on surfaces such as floors, bed rails, air ventilation units, mobile elements. These pathogens may be eliminated with proper disinfecting processes, including use appropriate surface disinfectants. In this study, we aimed to evaluate antibacterial effects seven disinfectants (HAMAYA, DAC, AJAX, Jif, Mr. MUSCLE, CLOROX, BACTIL) against eight bacterial strains Klebsiella pneumoniae, Enterobacter...
This research evaluated the most visible symptoms associated with coronavirus (COVID-19) vaccines among residents in Makkah of Saudi Arabia.A cross-sectional study was conducted 2021 a representative sample receiving COVID-19 vaccination at King Abdullah Medical City, Al Ukayshiyyah, and Umm Al-Qura University centers. A total 805 participants selected by census sampling method were included. Data regarding characteristics, medical history, post-vaccination obtained an interview-based...
This study estimates the point prevalence of symptomatic respiratory tract infections (RTIs) among returned Hajj pilgrims and their contacts in 2021. Using computer-assisted telephone interview (CATI) technique, domestic were invited to participate this cross-sectional survey two weeks after home return from Hajj. Of 600 approached, 79.3% agreed completed survey. Syndromic definitions used clinically diagnose possible influenza-like illnesses (ILI) COVID-19. Median with range was applied...
This study investigated the presence of COVID-19 cases among pilgrims, healthcare workers, and non-healthcare workers Hajj 2022. Nasopharyngeal samples were collected from 491 attendees All participants received three doses vaccines. Paired (n = 138; 69 participants) unpaired 422; 422 nasopharyngeal swabs subjected to RT-PCR targeting E gene β-coronaviruses RNA-dependent RNA polymerase SARS-CoV-2. Results linked participants' profiles including role during Hajj, respiratory symptoms or...
Abstract Background: This cohort study estimated the incidence of symptomatic respiratory tract infections (RTIs) and hand hygiene compliance with its impact among domestic Hajj pilgrims during COVID-19 pandemic. Methods: During week rituals in 2021, were recruited by phone asked to complete a baseline questionnaire. Pilgrims followed up after seven days using questionnaire about development symptoms, practices hygiene. Syndromic definitions used clinically diagnose ‘possible’ influenza-like...
The ongoing COVID-19 spreads worldwide with the ability to evolve in diverse human populations. nucleocapsid (N) protein is one of mutational hotspots SARS-CoV-2 genome. N an abundant RNA-binding critical for viral genome packaging. It comprises two large domains including N-terminal domain (NTD) and C-terminal (CTD) linked by centrally located linker region. Mutations have been reported increase severity disease modulating transmissibility, replication efficiency as well virulence...