A5018857446- Plant Molecular Biology Research
- Plant Reproductive Biology
- Genomics and Chromatin Dynamics
- Plant Virus Research Studies
- Chromosomal and Genetic Variations
- Fungal and yeast genetics research
- Genomics and Phylogenetic Studies
- DNA Repair Mechanisms
- Plant Gene Expression Analysis
- vaccines and immunoinformatics approaches
- Machine Learning in Bioinformatics
- Plant tissue culture and regeneration
- Microtubule and mitosis dynamics
- Photosynthetic Processes and Mechanisms
University of California, Davis
2014-2015
Centre for Cellular and Molecular Biology
2006-2014
The female gametophyte of flowering plants, called the embryo sac, develops from a haploid cell named functional megaspore, which is specified after meiosis by diploid sporophyte. In Arabidopsis, megaspore undergoes three syncitial mitotic divisions followed cellularization to form seven cells four types including two gametes. plant hormone auxin important for sporophytic developmental processes, and levels are known be regulated biosynthesis transport. Here, we investigated role...
In flowering plants, meiocytes develop from subepidermal cells in anthers and ovules. The mechanisms that integrate gene-regulatory processes with meiotic programs during reproductive development remain poorly characterized. Here, we show Arabidopsis thaliana plants deficient ACTIN-RELATED PROTEIN6 (ARP6), a subunit of the SWR1 ATP-dependent chromatin-remodeling complex, exhibit defects prophase I female meiosis. We found this defect is likely due to dysregulated expression genes,...
Abstract Background Pairing of homologous chromosomes at meiosis is an important requirement for recombination and balanced chromosome segregation among the products meiotic division. Recombination initiated by double strand breaks (DSBs) made Spo11 followed interaction DSB sites with a chromosome. This requires exchange proteins Rad51 Dmc1 that bind to single stranded regions created resection ends site DSBs promote interactions uncut DNA on partner. also considered be dependent factors...
Adherin plays an important role in loading the cohesin complex onto chromosomes, and is essential for establishment of sister-chromatid cohesion. We have identified analyzed Arabidopsis adherin homolog AtSCC2. Interestingly, sequence analysis AtSCC2 other putative plant homologs revealed presence a PHD finger, which not found their fungal animal counterparts. identical to EMB2773, mutants show early embryo lethality formation giant endosperm nuclei. A cohesion was established by using...
The establishment of sister chromatid cohesion followed by its controlled release at the metaphase to anaphase transition is necessary for faithful segregation chromosomes in mitosis and meiosis. Cohesion established action Ctf7/Eco1 on cohesin complex during DNA replication following loading onto chromatin Scc2-Scc4 complex. Ctf7 also required repair double strand breaks. contains an acetyltransferase domain a zinc finger motif acetylates conserved lysine residues Smc3 subunit cohesin. In...
The pandemicity & the ability of SARS-COV-2 to reinfect a cured subject, among other damaging characteristics it, took everybody by surprise. A global collaborative scientific effort was direly required bring learned people from different niches medicine data science together. Such platform provided COVID19 Virtual BioHackathon, organized 5th 11th April, 2020, ponder on related pressing issues varying in their diversity text mining genomics. Under "Machine learning" track, we...