A5087787331- Dementia and Cognitive Impairment Research
- Geriatric Care and Nursing Homes
- Mental Health and Patient Involvement
- Stroke Rehabilitation and Recovery
- Health Systems, Economic Evaluations, Quality of Life
- Frailty in Older Adults
- Noise Effects and Management
- Chronic Disease Management Strategies
- Hearing, Cochlea, Tinnitus, Genetics
- Cerebral Palsy and Movement Disorders
- Hearing Loss and Rehabilitation
- Subtitles and Audiovisual Media
- Physical Activity and Health
- Healthcare innovation and challenges
- Health and Wellbeing Research
- Mental Health and Psychiatry
- Aging, Elder Care, and Social Issues
- Facilities and Workplace Management
- Health disparities and outcomes
- Health Policy Implementation Science
- Interprofessional Education and Collaboration
- Balance, Gait, and Falls Prevention
- Pharmacy and Medical Practices
University of Nottingham
2019-2024
Queen's Medical Centre
2022-2024
Nottingham Biomedical Research Centre
2023
University of Ferrara
2023
Worcester Polytechnic Institute
2023
University of Puerto Rico System
2023
University Clinical Centre Maribor
2023
Stanford University
2023
Brighton and Sussex Medical School
2020
To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared usual care.Randomised controlled trial.Participants' homes communities at five sites United Kingdom.365 who were living home, family members carers.The intervention, Promoting activity, Independence, Stability Early Dementia (PrAISED), was a specially designed, specific, rehabilitation programme focusing on strength, balance, physical...
Abstract Background People with dementia progressively lose cognitive and functional abilities. Interventions promoting exercise activity may slow decline. We developed a novel intervention to promote independence prevent falls in people mild impairment (MCI) or early dementia. successfully undertook feasibility randomised controlled trial (RCT) refine the research delivery. are now delivering multi-centred RCT evaluate its clinical cost-effectiveness. Methods will recruit 368 MCI (Montreal...
Abstract Background We tested the feasibility of delivering and evaluating a complex therapy intervention which aimed to promote activity independence for people with early dementia (PrAISED). Feasibility questions were on: recruitment, randomisation, delivery, adherence withdrawals, level supervision required, adverse events, data collection sample size assumptions. Methods conducted three-arm, multi-site, single-blind, randomised controlled trial. Eligibility criteria aged 65 years or...
Abstract Background apathy, defined as reduced goal-directed activity, interests and emotion, is highly prevalent in neurocognitive disorders (NCDs). Apathy has important consequences for the individuals who experience it their carers, yet lived experiences of apathy this population are not well understood. Objective to explore how people with NCDs carers understand apathy. Method in-depth semi-structured interviews were conducted participants’ homes. Sixteen (dementia or mild cognitive...
Objective To explore the experiences of healthcare professionals working in falls prevention and memory assessment services providing assessments interventions for risk reduction people with dementia. Design This is a qualitative study using 19 semistructured interviews. Interviews were analysed through thematic analysis. Setting Community-based East Midlands, UK. Participants Nurses (n=10), physiotherapists (n=5), occupational therapists (n=3) psychiatrist (n=1). Results Three substantive...
Due to the progressive nature of dementia, it is important understand links between disease severity and health-related outcomes. The aim this study explore relationship quality life (QoL) people with dementia their family carers using a number disease-specific generic measures.In MODEM cohort study, three-hundred seven clinically diagnosed were recruited on quota basis provide equal numbers mild (standardised Mini-Mental State Examination (sMMSE), n = 110), moderate (sMMSE 10-19, 100),...
The PRomoting Activity, Independence and Stability in Early Dementia (PrAISED) study delivered an exercise functional activity programme to participants living with dementia. A Randomised Controlled Trial showed no measurable benefits activities of daily living, physical or quality life.
Abstract Background Research to date offers mixed evidence about the relationship between quality of life and severity cognitive impairment in people with dementia. We aimed investigate longitudinal changes patient- proxy-rated health-related (HRQL) by dementia explore factors associated HRQL over a one-year period. used data from MODEM cohort study which recruited dyads persons clinically diagnosed their principal carer interviewed them face-to-face at baseline again 1 year later. Methods...
Despite several interventions demonstrating benefit to people living with dementia and their caregivers, few have been translated implemented in routine clinical practice. There is limited evidence of the barriers facilitators for commissioning implementing health social care dementia. The aim current study was explore dementia, using a friendly exercise physical activity-based intervention (PrAISED [Promoting Activity, Stability Independence Early Dementia Mild Cognitive Impairment]) as case study.
Measuring physical activity (PA) in people with mild cognitive impairment or dementia can be difficult. The aim was to investigate the validity and acceptability of three different PA measurement methods. mixed-method analysis included 49 participants dementia, who completed a daily calendar recording PA, International Physical Activity Questionnaire, Longitudinal Aging Study Amsterdam those wore Misfit Shine accelerometer. quantitative showed equal completion rates for Questionnaire...
Abstract Hearing conditions such as hearing loss, tinnitus and hyperacusis are highly prevalent in the population can severely impact communication quality of life. is affected by multiple factors, including heredity, noise exposure, age, sex, ear disorders lifestyle factors. Globally, loss affects over 80% adults aged 80 years older, often experienced combination with other long-term health a mid-life risk factor for dementia. To form themed collection, we searched Age Ageing articles on...
Abstract Background Dementia is associated with frailty leading to increased risks of falls and hospitalisations. Interventions are required maintain functional ability, strength balance. Design Multi-centre parallel group randomised controlled trial, embedded process evaluation. Procedures were adapted during the COVID-19 pandemic. Participants People mild dementia or cognitive impairment (MCI), living at home, a family member carer. Objectives To determine effectiveness an exercise...
Abstract Background Despite several interventions demonstrating benefit to people living with dementia and their caregivers, few have been translated implemented in routine clinical practice. There is limited evidence of the barriers facilitators for commissioning implementing health social care dementia. The aim current study was explore a friendly exercise physical activity-based intervention (PrAISED (Promoting Activity, Stability Independence Early Dementia Mild Cognitive Impairment))...
Abstract There is a paucity of evidence relating to the implementation dementia care. The Promoting Activity, Independence and Stability in Early Dementia (PrAISED) intervention newly developed 12-month, home-based, individually tailored rehabilitation programme, delivered by therapists support workers, with focus on strength, balance, physical activity activities daily living. aim this study was identify what required implement PrAISED, or similar interventions, routine clinical practice....
Abstract Introduction People living with dementia and MCI progressively lose abilities, through increasing cognitive impairment, co-morbidities, inactivity, acute illnesses injuries. Rehabilitation therapy may reduce disability falls increase resilience. Methods We co-produced a intervention, comprising strength, balance dual-task exercises, functional activity training promoting community access, providing up to 50 sessions, delivered over 12 months underpinned by behaviour change strategy....
Abstract Introduction Hearing loss (HL) affects 12 million UK adults, including 70% of those aged over 70 years. It is associated with social isolation, anxiety, and depression. Furthermore, HL in midlife the largest modifiable risk factor for dementia. However, many individuals delay or avoid treatment. This may be due to limited understanding amongst public, considerable stigma surrounding hearing aids. The media play a crucial role shaping public perceptions age-related conditions....
Abstract Background The PRomoting Activity, Independence and Stability in Early Dementia (PrAISED) study delivered an exercise functional activity programme to participants living with dementia. A Randomised Controlled Trial (RCT) showed no measurable benefits activities of daily living, physical or quality life. Objective To explore participants’ responses PrAISED explain the mechanisms behind a complex intervention that did not lead expected health gains. Methods process evaluation using...
Apathy, defined as reduced goal-directed activity, social engagement and emotion, is highly prevalent in dementia Mild Cognitive Impairment (MCI), has important consequences for the individuals that experience it those who care them. However, lived experiences of this population not well understood. This study aimed to explore how people with MCI their carers apathy.People early living four geographical areas England were invited take part a qualitative interview. All participants had...