A5102776475- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Viral Infections and Immunology Research
- Virus-based gene therapy research
- Microbial infections and disease research
- Gut microbiota and health
- Virology and Viral Diseases
- Viral gastroenteritis research and epidemiology
- Transplantation: Methods and Outcomes
- Plant Virus Research Studies
- RNA Research and Splicing
- Advanced Sensor and Energy Harvesting Materials
- RNA modifications and cancer
- Dietary Effects on Health
- interferon and immune responses
- Coastal wetland ecosystem dynamics
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Cancer-related molecular mechanisms research
- Nanoplatforms for cancer theranostics
- Soil erosion and sediment transport
- Supercapacitor Materials and Fabrication
- Conducting polymers and applications
- Flood Risk Assessment and Management
- Graphene and Nanomaterials Applications
Yanshan University
2025
State Key Laboratory of Metastable Materials Science and Technology
2025
Southern Medical University
2021-2024
Hebei Normal University of Science and Technology
2024
China Aerospace Science and Industry Corporation (China)
2021-2024
Zhujiang Hospital
2021-2024
Dalian Medical University
2023
First Affiliated Hospital of Dalian Medical University
2023
Qingdao Center of Resource Chemistry and New Materials
2023
Zhejiang University of Finance and Economics
2022
Abstract Background The gut microbiota is reportedly involved in the progression and chemoresistance of various human malignancies. However, underlying mechanisms behind how it exerts some effect on prostate cancer, as an extra-intestinal tumor, a contact-independent way remain elusive deserve exploration. Antibiotic exposure, one factors affecting community capable causing dysbiosis, associated with multiple disorders. This study aims to preliminarily clarify link between dysbiosis cancer....
Abstract The cyclic guanosine monophosphate‐adenosine monophosphate synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway is an important innate immune that has shown remarkable potential in cancer immunotherapy. However, the clinical therapeutic efficacy limited due to insufficient penetration STING agonists into tumors. In this study, a special piezo‐STING agonist (ZnS‐Cur@CM, Z/C@M) composed zinc sulfide nanosheets, curcumin, and tumor cell membranes based on principle...
Wetland vegetation dynamics are vital but difficult to understand due complex impact factors and their spatial heterogeneities. Poyang Lake, the largest freshwater lake in China, is well-known for its ecological importance as a floodplain wetland. However, heterogeneity extent response water regimes across different geomorphic units of Lake remain unclear date. To address this gap, Landsat images acquired during dry seasons from 1987 2018 were selected explore level fluctuations multiple...
The effects of 5-methylcytosine in RNA (m5C) various human cancers have been increasingly studied recently; however, the m5C regulator signature prostate cancer (PCa) has not well established yet. In this study, we identified and characterized a series m5C-related long non-coding RNAs (lncRNAs) PCa. Univariate Cox regression analysis least absolute shrinkage selector operation (LASSO) were implemented to construct lncRNA prognostic signature. Consequently, m5C-lnc model was established,...
Abstract Background Anatid herpesvirus 1 (AHV-1) is an alphaherpesvirus associated with latent infection and mortality in ducks geese currently affecting the world-wide waterfowl production severely. Here we describe a fluorescent quantitative real-time PCR (FQ-PCR) method developed for fast measurement of AHV-1 DNA based on TaqMan MGB technology. Results The detection limit assay was × 10 standard copies, sensitivity 2 logs higher than that conventional gel-based targeting same gene....
Abstract Background Goose parvovirus (GPV) is a Dependovirus associated with latent infection and mortality in geese. Currently, it severely affects geese production worldwide. The objective of this study was to develop fluorescent quantitative real-time polymerase chain reaction (PCR) (FQ-PCR) assay for fast accurate quantification GPV DNA infected goslings, which can aid the understanding regular distribution pattern nosogenesis vivo. Results detection limit 2.8 × 10 1 standard copies,...
Prostate cancer (PCa) is one of the most common malignancies among male patients with pathology worldwide. Owing to inevitable development irremediable castration-resistant prostate (CRPC) following intervention androgen deprivation therapy, new therapeutic strategies are in great demand. Ganoderma lucidum, a medicinal fungus, has recently been reported be potential antitumor agent. However, whether water extract sporoderm-broken spores G. lucidum (BSGWE), special approach obtain whole...
Knowledge of the subcellular localization a protein can provide useful insights about its function. While many alphaherpesvirus UL51 proteins has been well characterized, little is known where duck enteritis virus (DEV) (pUL51) targeted to. Thus, in this study, we investigated and distribution DEV pUL51 by computer aided analysis, as indirect immunofluorescence (IIF) transmission immunoelectron microscopy (TIEM) approaches DEV-infected cells.The gene product was identified an approximate 34...
The UL24 gene of duck enteritis virus (DEV) is conserved across herpesviruses, but its protein characterization has not been reported. We expressed the in Escherichia coli BL21 from a recombinant plasmid pET32a/DEV-UL24 and used resulting to raise antiserum. This antiserum recognized 38-kDa lysates infected cells. SDS-PAGE analysis showed that partial was highly after induction by 0.4 mM IPTG at 30 degrees for 6 h. results purification revealed expression more purified using method...
Environmental deterioration in urbanizing areas increases the risks of sudden death as well chronic, infectious, and psychological diseases. Quantifying health-related physical environment can assess health risk urban residents. This study uses an integrated evaluation method to simulate four dimensions acoustic, wind, thermal, landscape. According case one university campus area China, results show that (1) with unqualified equivalent A sound levels are generally sports area, green square 1...
Background: Prostate cancer (PCa) is one of the most common cancers in males around globe, and about one-third patients with localized PCa will experience biochemical recurrence (BCR) after radical prostatectomy or radiation therapy. Reportedly, a proportion BCR had poor prognosis. Cumulative studies have shown that RNA modifications participate cancer-related transcriptome, but role pseudouridylation occurring lncRNAs remains opaque. Methods: Spearman correlation analysis univariate Cox...
In order to define clearly the conditions leading outcome of acute duck hepatitis B virus (DHBV) infection, 1-day-old Pekin ducklings were infected with DHBV by different routes and given doses inoculum. Groups 24 inoculated either intravenously via vena cruralis, or intraperitoneally pooled serum containing 1.6 x 107 104 genomes. One control from each group was an equal volume normal serum. A sensitive reproducible real-time polymerase chain reaction assay based on TaqMan technology...