Tadashi Nosaka

ORCID: 0000-0002-4925-8665
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About
Contact & Profiles
Research Areas
  • Bipolar Disorder and Treatment
  • Schizophrenia research and treatment
  • Electroconvulsive Therapy Studies
  • Treatment of Major Depression
  • Tryptophan and brain disorders
  • Attention Deficit Hyperactivity Disorder
  • Pharmaceutical studies and practices
  • Adolescent and Pediatric Healthcare
  • Diet and metabolism studies
  • Electrolyte and hormonal disorders
  • Dementia and Cognitive Impairment Research
  • Congenital Heart Disease Studies
  • Conservation Techniques and Studies
  • Mental Health Treatment and Access
  • Cardiac Health and Mental Health
  • Thyroid and Parathyroid Surgery
  • Lipoproteins and Cardiovascular Health
  • Family Caregiving in Mental Illness
  • Tissue Engineering and Regenerative Medicine
  • Diet, Metabolism, and Disease
  • Chronic Disease Management Strategies
  • Complex Systems and Time Series Analysis
  • COVID-19 Clinical Research Studies
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Liver Disease Diagnosis and Treatment

Sumitomo Dainippon Pharma (Japan)
2019-2025

Vion Pharmaceuticals (United States)
2021

Sunovion (United States)
2021

Sumitomo Dainippon Pharma (United States)
2018-2020

Schizophrenia places a great humanistic and financial burden to patients, families, societies, the is substantially impacted by comorbid conditions. This study aimed estimate lifetime prevalence of schizophrenia assess health-related quality life (HRQoL), work productivity, indirect cost among patients with without comorbidities (depressive symptoms, sleep disturbances, anxiety problems).This secondary analysis existing data collected in 2019 from Japan National Health Wellness Survey. The...

10.1186/s12888-022-04044-5 article EN cc-by BMC Psychiatry 2022-06-18

To evaluate the relationship between cognitive impairment and work productivity loss in patients with bipolar disorder. We enrolled outpatients disorder aged 18-59 years undergoing treatment actively employed or on sick leave. Baseline demographic, medical resource use, employment data were collected. evaluated productivity, impairment, quality of life (QOL), depressive symptoms (defined as a Patient Health Questionnaire-9 [PHQ-9] score ≥ 10), sleep disturbance. This interim analysis...

10.1002/npr2.70012 article EN cc-by Neuropsychopharmacology Reports 2025-03-01

Previous studies have shown that bipolar disorder (BD) patients frequently present with difficulties in interpersonal relationships, education or employment and suffer poorer quality of life. This study aimed to estimate the impact BD on health-related life (HRQOL), work productivity loss indirect costs.Data was from online, self-administered 2019 National Health Wellness Survey. Outcomes were compared for those who self-reported a physician diagnosis (N=179), major depressive (MDD, N=1,549)...

10.1016/j.jad.2021.07.104 article EN cc-by Journal of Affective Disorders 2021-08-01

Aim The aim of this study was to evaluate the efficacy lurasidone in acute schizophrenia Japan and other countries. Methods Subjects (aged 18–74 years) diagnosed with were randomized 40 mg/day or placebo. primary endpoint change from baseline on Positive Negative Syndrome Scale (PANSS) total score at Week 6. Secondary assessments included Clinical Global Impression‐Severity (CGI‐S). Safety endpoints adverse events, laboratory electrocardiogram parameters. Results A 483 subjects placebo; 107...

10.1111/pcn.13221 article EN cc-by Psychiatry and Clinical Neurosciences 2021-04-23

Abstract Background Bipolar disorder often emerges from depressive episodes and is initially diagnosed as depression. This study aimed to explore the effects of a prior depression diagnosis on outcomes in patients with bipolar disorder. Methods cohort analyzed data aged 18–64 years who received new Japan, using medical claims January 2005 October 2020 provided by JMDC, Inc. The index month was defined time diagnosis. assessed incidence psychiatric hospitalization, all‐cause mortality,...

10.1002/npr2.12457 article EN cc-by-nc-nd Neuropsychopharmacology Reports 2024-07-02

Abstract Background Lurasidone is once a day oral medication, which could be administered any time of the day, but relationship between timing administration and risk developing adverse events has not been systematically evaluated. The purpose this study was to examine whether there difference in lurasidone morning at night treatment adult schizophrenia. Methods Randomized placebo-controlled trials (RCTs) adults with acute exacerbation schizophrenia were analyzed for incidence akathisia,...

10.1093/schbul/sbaa031.071 article EN cc-by-nc Schizophrenia Bulletin 2020-04-01

Abstract Background Bipolar disorder often emerges from depressive episodes and is initially diagnosed as depression. This study aimed to explore the effects of a prior depression diagnosis on outcomes in patients with bipolar disorder. Methods cohort analyzed data aged 18–64 years who received new Japan, using medical claims January 2005 October 2020 provided by JMDC, Inc. The index month was defined time diagnosis. assessed incidence psychiatric hospitalization, all-cause mortality,...

10.21203/rs.3.rs-3976192/v1 preprint EN 2024-02-23
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