- Treatment of Major Depression
- Mental Health Research Topics
- Schizophrenia research and treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Bipolar Disorder and Treatment
- Mental Health Treatment and Access
- Electroconvulsive Therapy Studies
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health and Psychiatry
- Health Systems, Economic Evaluations, Quality of Life
- Psychosomatic Disorders and Their Treatments
- Health, psychology, and well-being
- Cardiac Health and Mental Health
- Functional Brain Connectivity Studies
- Psychiatric care and mental health services
- Health disparities and outcomes
- Personality Disorders and Psychopathology
- Tryptophan and brain disorders
- Obsessive-Compulsive Spectrum Disorders
- Neurological disorders and treatments
- Psychotherapy Techniques and Applications
- Musculoskeletal pain and rehabilitation
- Suicide and Self-Harm Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Workplace Health and Well-being
University of Copenhagen
2012-2022
Copenhagen University Hospital
2008-2022
Zealand University Hospital
2006-2022
Region Zealand
2011-2020
Centre for Mental Health
2014-2018
Zucker Hillside Hospital
2017
Albert Einstein College of Medicine
2017
Aalborg University Hospital
2004-2016
Lundbeck (Denmark)
2016
National Research Centre for the Working Environment
2016
Abstract The health status questionnaire Short‐Form 36 (SF‐36) includes subscales measuring both physical and mental health. Psychometrically, the subscale contains a mixture of symptoms psychological well‐being items, among other things, to prevent ceiling effect when used in general population studies. Three items are also included WHO‐Five scale. In Danish study, was compared psychometrically with order evaluate effect. Tests for unidimensionality were psychometric analyses, sensitivity...
Background. We have developed the Major Depression Inventory (MDI), consisting of 10 items, covering DSM-IV as well ICD-10 symptoms depressive illness. aimed to evaluate this a scale measuring severity states with reference both internal and external validity. Method. Patients representing score range from no depression marked on Hamilton Scale (HAM-D) completed MDI. Both classical modern psychometric methods were applied for evaluation validity, including Rasch analysis. Results. In total,...
Background: In a European trial in 8 countries, the subjective well-being of patients on alternative forms treatment for insulin-dependent diabetes was compared using 28-item WHO Well-Being Questionnaire, covering four dimensions depression, anxiety, energy and positive well-being. The objective analysis reported here has been to identify items questionnaire which belong an overall index negative Methods: Adult at 10 study centres countries who had insulin least 2 years were invited...
A step‐by‐step analysis of Beck's and Hamilton's rating scales showed that both, failed to differentiate adequately between moderate severe depression measured by a global clinical assessment. Each item the was tested for calibration, ascending monotonicity, dispersion parallel Twelve items scale six were found valid with respect these criteria. Those should be taken into account in future research baseline ratings change depressive states quantitatively.
This paper presents the results of a detailed study pain epidemiology and health related quality life (HRQL) in 150 chronic non-malignant patients consecutively referred to Danish multidisciplinary center. Mean severity was 71.6 (SD=18.5) on VAS scale. Forty-two percent reported poor sleep. HRQL evaluated with Medical Outcome Study-Short Form (SF-36), Hospital Anxiety Depression scale (HAD) Psychological General Well-Being Scale (PGWB). Compared normal population (NP) both SF-36 scores PGWB...
The consistency of the Hamilton Depression Scale (HDS) as a measure severity depressive states has been examined when scale was used weekly during trial with imipramine. By use logistic models (Rasch) HDS considered across patient‐variables age, sex, plasma levels imipramine, and diagnosis. results showed that original 17‐item without adequate consistency, i.e. total score sample items no one‐dimensional states. However, melancholia subscale contained which can be to compare patients...
In a study of 18 patients with manic symptomatology and 31 melancholic the Bech‐Rafaelsen Mania Scale (BRMS) Hamilton Depression (HDS) have been compared. The results showed that inter‐observer reliability BRMS was adequate compared HDS. Both scales are constructed for assessing severity or states, no difference found in total HDS score between various diagnostic groups, when were classified by an index course their disorder, using Multi‐axial Classification System Affective Disorders...
The current criteria for major depression (1) have been criticized the heterogeneity of clinical syndrome they define. This has led to suggestions alternative classifications, most recently by G. Parker in this journal (2). According critics, polymorphic is partly blame fact that treatment still not moved beyond trial and error approach genetics neurobiology underlying depressive disorder remain largely unknown without practical significance (3). Two interesting studies on depression,...
The Major Depression Inventory (MDI) was developed to cover the universe of depressive symptoms in DSM-IV major depression as well ICD-10 mild, moderate, and severe depression. objective this study evaluate standardization MDI a severity scale using Visual Analogue Scale (VAS) index external validity accordance with LEAD approach (Longitudinal Expert Assessment All Data). We used data from two previously published studies which patients had MINI Neuropsychiatric Interview verified diagnosis...
This report describes the GRID-Hamilton Depression Rating Scale (GRID-HAMD), an improved version of Hamilton that was developed through a broad-based international consensus process. The GRID-HAMD separates frequency symptom from its intensity for most items, refines several problematic anchors, and integrates both structured interview guide consensus-derived conventions all items. Usability established in small three-site sample convenience, evaluating 29 outpatients, with evaluators...
Objective: To evaluate the internal validity of subscales combined SCL‐90 and SCL‐90R, SCL‐92, by item response analyses as compared with several previously reported factor this questionnaire in literature. Method: The SCL‐92 was mailed to an age‐ gender‐stratified random sample Danish citizens. comprised 2040 individuals. structure nine factors evaluated Mokken‐Loevinger analysis Rasch analysis. Results: In total, 1153 persons or 58% returned fully completed. Mokken found all scales apart...
To estimate the prevalence rate of major depression in Danish general population by using Major Depression Inventory (MDI), a validated self-rating scale fulfilling symptomatic criteria DSM-IV and ICD-10 for depressive episode.A booklet containing MDI number questions on psychosocial factors was sent to 2040 randomly selected citizens. The sample age- gender-stratified. Mean scores were calculated. Logistic regression analysis used order produce model influence factors.The response 60%....
Abstract The present study had two aims. first was to evaluate the reliability and validity of Japanese version World Health Organization (WHO)‐Five Well‐Being Index (WHO‐5‐J) as a brief well‐being scale. second examine discriminatory this test screening tool for current depressive episodes in diabetic patients. A sample 129 patients completed WHO‐5‐J. Of these, 65 were also interviewed by psychiatrists assess whether they any according DSM‐IV. internal consistency evaluated using Cronbach’s...