John Brazier

ORCID: 0000-0001-8645-4780
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About
Contact & Profiles
Research Areas
  • Health Systems, Economic Evaluations, Quality of Life
  • Economic and Environmental Valuation
  • Global Health Care Issues
  • Healthcare Policy and Management
  • Clostridium difficile and Clostridium perfringens research
  • Healthcare cost, quality, practices
  • Health disparities and outcomes
  • Viral gastroenteritis research and epidemiology
  • Delphi Technique in Research
  • Microscopic Colitis
  • Bacterial Identification and Susceptibility Testing
  • Retinal Diseases and Treatments
  • Antimicrobial Resistance in Staphylococcus
  • Economic and Financial Impacts of Cancer
  • Streptococcal Infections and Treatments
  • DNA and Nucleic Acid Chemistry
  • Pharmaceutical Economics and Policy
  • Nosocomial Infections in ICU
  • Health Policy Implementation Science
  • Statistical Methods in Clinical Trials
  • Clinical practice guidelines implementation
  • Otolaryngology and Infectious Diseases
  • Mental Health and Patient Involvement
  • Primary Care and Health Outcomes
  • Psychological Well-being and Life Satisfaction

University of Sheffield
2016-2025

Somerset County Council
2025

University of Bonn
2024

University of Hertfordshire
2024

University of Reading
2012-2023

University of Bristol
2023

The University of Melbourne
2022

University of Technology Sydney
2013-2022

Simon Fraser University
2022

Trinity Western University
2022

Background: The SF-12 is a multidimensional generic measure of health-related quality life. It has become widely used in clinical trials and routine outcome assessment because its brevity psychometric performance, but it cannot be economic evaluation current form. Objectives: We sought to derive preference-based health from the for use compare with original SF-36 index. Research Design: was revised into 6-dimensional state classification (SF-6D [SF-12]) based on an item selection process...

10.1097/01.mlr.0000135827.18610.0d article EN Medical Care 2004-08-19

Abstract As the number of preference‐based instruments grows, it becomes increasingly important to compare different measures health in order inform an debate on choice instrument. This paper presents a comparison two them, EQ‐5D and SF‐6D (recently developed from SF‐36) across seven patient/population groups (chronic obstructive airways disease, osteoarthritis, irritable bowel syndrome, lower back pain, leg ulcers, post menopausal women elderly). The mean index value was found exceed by...

10.1002/hec.866 article EN Health Economics 2004-01-09

A reference library of types Clostridium difficile has been constructed by PCR ribotyping isolates (n = 2,030) from environmental 89), hospital 1,386), community practitioner 395), veterinary 27), and 133) sources. The consists 116 distinct identified on the basis differences in profiles generated with primers designed to amplify 16S-23S rRNA gene intergenic spacer region. Isolates 55% infections hospitals United Kingdom belonged one ribotype (type 1), but this type was responsible for only...

10.1128/jcm.37.2.461-463.1999 article EN Journal of Clinical Microbiology 1999-02-01

Recently the National Institute for Clinical Excellence (NICE) updated its methods guidance technology assessment. One aspect of new is to require use probabilistic sensitivity analysis with all cost-effectiveness models submitted Institute. The purpose this paper place NICE on dealing uncertainty into a broader context requirements decision making; explain general approach that was taken in development; and address each issues which have been raised debate about role general. most...

10.1002/hec.985 article EN Health Economics 2005-01-01

The SF-6D is a new single summary preference-based measure of health derived from the SF-36. Empirical work required to determine what smallest change in scores that can be regarded as important and meaningful for professionals, patients other stakeholders. To use anchor-based methods minimally difference (MID) various datasets. All responders original SF-36 questionnaire assigned an score provided 11 items used have been completed. continuous outcome scored on 0.29 1.00 scale, with...

10.1186/1477-7525-1-4 article EN cc-by Health and Quality of Life Outcomes 2003-01-01
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