A5101669879- Advanced Drug Delivery Systems
- Cancer Treatment and Pharmacology
- Chemotherapy-induced cardiotoxicity and mitigation
- Dietary Effects on Health
- Epigenetics and DNA Methylation
- Birth, Development, and Health
- Chemotherapy-induced organ toxicity mitigation
- Drug Solubulity and Delivery Systems
- Genetics, Aging, and Longevity in Model Organisms
- Oral microbiology and periodontitis research
- Toxin Mechanisms and Immunotoxins
- Plant-based Medicinal Research
- Synthesis and Biological Evaluation
- Gut microbiota and health
- Oral and gingival health research
- Corneal Surgery and Treatments
- Inhalation and Respiratory Drug Delivery
- Acute Lymphoblastic Leukemia research
- Adipose Tissue and Metabolism
- Biological Activity of Diterpenoids and Biflavonoids
- Cholinesterase and Neurodegenerative Diseases
- Ocular Surface and Contact Lens
- Berberine and alkaloids research
- Tryptophan and brain disorders
Narsee Monjee Institute of Management Studies
2020-2024
Young blood plasma is known to confer beneficial effects on various organs in mice and rats. However, it was not whether from young adult pigs rejuvenates old rat tissues at the epigenetic level; alters clock, which a highly accurate molecular biomarker of aging. To address this question, we developed validated six different clocks for that are based DNA methylation values derived n = 613 tissue samples. As indicated by their respective names, pan-tissue clock can be applied profiles all...
Abstract Young blood plasma is known to confer beneficial effects on various organs in mice. However, it was not whether young rejuvenates cells and tissues at the epigenetic level; alters clock, which a highly-accurate molecular biomarker of aging. To address this question, we developed validated six different clocks for rat that are based DNA methylation values derived from n=593 tissue samples. As indicated by their respective names, pan-tissue clock can be applied profiles all tissues,...
The current study evaluates the effect of chelidonic acid on doxorubicin-induced cardiac toxicity. Chelidonic (CA) is a natural pyran-skeleton heterocyclic compound found in rhizomes perennial plant, celandine (Chelidonium majus).
ABSTRACT Young blood plasma is known to confer beneficial effects on various organs in mice and rats. However, it was not whether from young pigs rejuvenates old rat tissues at the epigenetic level; alters clock, which a highly accurate molecular biomarker of aging. To address this question, we developed validated six different clocks for that are based DNA methylation values derived n=613 tissue samples. As indicated by their respective names, pan-tissue clock can be applied profiles all...
Aging and, in particular, the emergence of age-related disorders is associated with tissue dysfunction and macromolecular damage, some which can be attributable to accumulated oxidative damage. In current study, we determine potential 'plasma-derived fraction (E5)' for cellular rejuvenation extending lifespan Sprague Dawley (SD) rats. This a unique study wherein have used 24-month-old rats monitored them until end their without E5 treatment. present investigation, SD were separated into two...
Abstract: Objectives: Mouth ulcer is a rupture or breaks in the oral mucosal membrane and it leads to atrophy ulcers cavity. It increases risk of infections with Candida species Inherited trauma aphthous stomatitis, disorder characterised by recurrent production for unknown reasons, are most common causes ulceration. Study Design: This study aimed develop two separates buccal mucoadhesive films, using model drug deglycyrrhizinated liquorice chlorhexidine gluconate. The film was assessed...
Chelidonic acid is a phytoconstituent found in rhizomes of the perennial plant celandine. The current study aims to evaluate acute and repeated dose oral toxicity chelidonic as per OECD guidelines 425 407. pharmacokinetic profile was predicted using online servers tools. A single (2000 mg/kg) administered female Wistar rats an study, animals were monitored for 14 days. We studied at 10, 20, 40 mg/kg doses (28 days). Clinical biochemistry, haematological, urine parameters estimated. gross...