A5084045123- Dementia and Cognitive Impairment Research
- Neurology and Historical Studies
- Neurobiology of Language and Bilingualism
- Alzheimer's disease research and treatments
- Spatial Neglect and Hemispheric Dysfunction
- Mental Health and Psychiatry
- History of Medicine Studies
- Neurological disorders and treatments
- Meta-analysis and systematic reviews
- Parkinson's Disease Mechanisms and Treatments
- EEG and Brain-Computer Interfaces
- Pharmaceutical industry and healthcare
- Memory and Neural Mechanisms
- Functional Brain Connectivity Studies
- Reading and Literacy Development
- Neuroscience, Education and Cognitive Function
- Action Observation and Synchronization
- Neurological Disorders and Treatments
- Visual perception and processing mechanisms
- History of Medical Practice
- Neural and Behavioral Psychology Studies
- Epilepsy research and treatment
- Language Development and Disorders
- Neurological Disease Mechanisms and Treatments
- Health Systems, Economic Evaluations, Quality of Life
George Washington University
2014-2025
Tokyo Women's Medical University
2019
Clinique Valmont
2019
Washington University Medical Center
2015
National Institute of Mental Health
2011
Inserm
1998-2009
Centre Paul Broca
1994-2007
University of Pittsburgh
1981-2005
Fremantle Hospital
2005
University of Perugia
2005
We investigated the role of perceptual and motor factors in visuospatial impairment 30 patients with Parkinson's disease (PD) matched controls. All subjects were administered tests, which included "visuoperceptual" tasks, requiring minimal responses, "visuomotor" tasks. The performance PD was considerably impaired on several tasks from both groups, this not related to depression or intellectual impairment. Patients stage 3 tended show greatest Those 1 (unilateral symptoms), however, more...
Journal Article SIMPLE REACTION TIME: EVIDENCE FOR FOCAL IMPAIRMENT FROM LESIONS OF THE RIGHT HEMISPHERE Get access DAVIS HOWES, HOWES Neurology Department, Boston Veterans Administration Hospital, and University School of Medicine; Service, Cleveland Case Western Reserve Medical Search for other works by this author on: Oxford Academic PubMed Google Scholar FRANCOIS BOLLER Brain, Volume 98, Issue 2, 1975, Pages 317–332, https://doi.org/10.1093/brain/98.2.317 Published: 01 April 1975 history...
Abstract We present the first results of a cognitive stimulation programme for patients with dementia. Fifty‐six subjects entered study involving two parallel, randomized groups. Assessment was blind main criteria (neuropsychological tests). Twenty‐nine were stimulated and compared to 27 non‐stimulated patients. The group attended 10 sessions over 5 weeks. Each assessed on seventh week. Following stimulation, there significant improvement Mini‐Mental State (MMS) scores ( p < 0.01)...
Journal Article LATENT SENSORY APHASIA IN HEMISPHERE-DAMAGED PATIENTS: AN EXPERIMENTAL STUDY WITH THE TOKEN TEST Get access F. BOLLER, BOLLER From the Clinica delle Malattie Nervose e Mentali, University of Milano Search for other works by this author on: Oxford Academic PubMed Google Scholar L. A. VIGNOLO Brain, Volume 89, Issue 4, December 1966, Pages 815–830, https://doi.org/10.1093/brain/89.4.815 Published: 01 1966
To examine whether the use of psychiatric medication and presence abnormal behaviors affects progression Alzheimer disease.Cross-sectional with longitudinal follow-up likelihood arriving at 4 end points: (1) Mini-Mental State Examination score 9 or lower; (2) Blessed Dementia Rating Scale 15 higher for activities daily living; (3) nursing home admission; (4) death, evaluated using a proportional hazard model variables: psychosis, insomnia, wandering, aggression, psychomotor agitation,...
Senile plaques (SPs), especially, and neurofibrillary tangles are important pathologic markers for the diagnosis of Alzheimer's disease (AD), but neither is pathognomonic AD. We hypothesize that elevations in levels phosphomonoesters, precursors membrane phospholipids, occur early pathogenesis AD precede appearance SPs. In contrast, phosphodiesters, breakdown products reflect degeneration neural membranes will correlate with Correlative phosphorus-31 magnetic resonance spectroscopy...
In this study we used semantic-priming procedures to examine limitations in the use of semantic context by patients with Alzheimer's disease. We also tried determine whether any such contextual effects were mediated solely through automatic processes or attentional involved. Three tasks applied effect on performance 18 normal elderly and young subjects, When demented subjects asked decide a given item was member certain category, results showed that their response times equally affected...
Recent work has suggested that patients with damage to temporal lobe structures, such as Alzheimer's Disease (AD), lose information from memory at an abnormally rapid rate. In contrast, data other studies suggest the rate of forgetting in AD is normal. present study, 62 mild moderate and 64 elderly controls were tested for their immediate delayed recall a short verbal passage modified Rey complex figure. The results although recalled less than controls, they did not forget faster during 30...
The fluorescence anisotropy of 1,6-diphenyl-1,3,5-hexatriene in labeled platelet membranes, an index membrane fluidity, identifies a prominent subgroup patients with Alzheimer's disease who manifest distinct clinical features. In family study, the prevalence this abnormality was 3.2 to 11.5 times higher asymptomatic, first-degree relatives probands than neurologically healthy control subjects chosen without regard history dementia. pattern within families consistent that fully penetrant...
Familial idiopathic basal ganglia calcification (IBGC, Fahr disease) is an inherited neurologic condition characterized by and extra-basal brain calcifications, parkinsonism, neuropsychiatric symptoms. The authors examined six families for linkage to the previously identified genetic locus (IBGC1) located on chromosome 14q. found evidence against IBGC1 in five of supporting previous preliminary studies demonstrating heterogeneity familial IBGC.
Double-blind fluorescence studies of platelet membrane fluidity were conducted at 37 degrees C for 51 patients with Alzheimer-type dementia, 24 nondemented depressed patients, and 50 neurologically healthy subjects. The the hydrocarbon region membranes from demented group, as reflected by steady-state anisotropy fluorescent probe 1,6-diphenyl-1,3,5-hexatriene (DPH), was significantly greater than that normal control Within correlated severity dementia but not duration illness or age onset....