For the Krasnodar Territory, West Nile fever (WNF) is an emergent infection with insufficiently studied clinical and epidemiological manifestations. The question of role urban environment in formation new endemic foci remains open. Objective study: to characterize main manifestations WNF determine possible location city using example 2019 outbreak. Methods. A retrospective analysis 78 inpatient observation cards for confirmed by ELISA PCR was conducted. selection condition presence patients...

Background. The new coronavirus infection has manifested untypically compared to other acute respiratory agents, posing a major challenge researchers worldwide. Despite low incidence of bacterial complications, microbial coinfection plays an important role in the onset and development severe COVID-19 hamper diagnosis, treatment prognosis. Objectives. A study landscape secondary complications prevailing microbial-agent antibiotic resistance dynamics vs. patients with pre-COVID...

The purpose of research - based on analysis the clinical-epidemiologic data, level viral load and prevalence HCV genotypes to determine current consistencies epidemiological trends development HCV-infection in area Krasnodar Territory. Patients methods. Population incidence hepatitis C Territory was studied for period from 2004 2011. Clinical manifestations disease we evaluated base a retrospective 1913 hospital records patients with chronic C. There were investigated results 19,338...

The purpose of the study - detection clinical and epidemiological peculiarities sepsis in patients admitting to Infectious Diseases Unit on base analysis hospital cohort. Patients methods There was studied Hospital cohort Krasnodar Specialized Disease for period from 2010 2014, there were analyzed both frequency registration structure mortality rate. course records considered 81 patients. Results. percentage infectious clinic accountedfor 0.28%. In lethal outcomes, share amounted one fourth...

The aim of the study. analysis clinical and epidemiological peculiarities tuberculosis associated with HIV infection (TB+HIV), in Tula region for 16 years from 1995 to 2012 determine priority directions prevention improvement quality medical care. Materials methods. There was executed retrospective 818 inpatient records TB+HIV patients 645 outpatient cards (Tula regional antitubercular dispensary N1). Patients were observed examined also Center Prevention Control ofAIDS Infectious diseases....

Background . The incidence of invasive mycoses is reported to increase among patients with a history new coronavirus infection COVID-19. Adhesion and damage endothelial cells by zygomycetes lead fungus angioinvasion, release large number fungal proteases, lipases mycotoxins, as well vascular thrombosis, subsequent necrosis tissues. Objectives Improvement the diagnosis treatment for COVID-19 associated mycosis. Methods Examination 143 mycosis maxillofacial area in period from August 2021 May...

The article gives an analysis of domestic and foreign literature reports, as well the author’s own experience in problem rabies. There are presented facts on etiology, pathogenesis, epidemiology Details features clinical laboratory diagnosis issues treatment prevention considered. An algorithm for management patients with suspected rabies is suggested.

The purpose of the study. improvement diagnosis oftuberculosis in HIV-infected patients on basis ofa comparative study tissue reactions immunecompetent organs disseminated tuberculosis and changes immunological status at different stages HIV infection. Materials methods. Pathological studies were performed autopsy material 11 cases with infection, 6 observations Studies indices response was 60 pulmonary (DPT) agedfrom 18 to 49 years, associated infection - 30 people (DPT + HIV) first group;...

The purpose of the study improvement early diagnostics Lyme disease on based clinical and epidemiological analysis main forms acute course in new natural foci Krasnodar Krai. Patients methods. There was analyzed data for 207 patients period within from 2004 to 2013. Results. In territory Krai Republic Adygea there has formed a set tick-borne borreliosis (TB), i.e. (LD). infection cases is observed not only disease, but also city limits. registered mainly erythematous form (74% patients),...

BACKGROUND: The growth of fungal pathology observed in the last decade, including life-threatening invasive mycoses, is associated with spread immunodeficiency states various etiologies. COVID-19 pandemic has made a negative contribution, causing significant increase number patients complications.
 AIM: To characterize types complications acute period new coronavirus infection based on an analysis clinical course and therapeutic tactics for managing underlying disease.
 MATERIALS...

BACKGROUND: Community-acquired Legionella pneumonia, classified as atypical is an important problem worldwide. Late initiation of etiotropic therapy for Legionnaires’ disease worsens the prognosis and increases risk death.
 AIM: To clinically epidemiologically characterize using data on its incidence in Krasnodar region to attract attention doctors timely diagnosis prescription adequate therapy.
 MATERIALS AND METHODS: A hospital cohort 26 patients who were hospitalized between...

The high incidence of community-acquired pneumonia during the COVID-19 pandemic requires early differential diagnosis because differences in patient management techniques. Among pneumonias, legionelliosis deserves special attention. difficulty clinical legionellosis leads to untimely prescription specific antibacterial therapy, which worsens prognosis. This study presents examples that draw attention specialists clinical, laboratory, and radiological features important role epidemiological...

Aim . Clinical, epidemic and laboratory characterisation of ixodic tick-borne borreliosis in order to improve the early diagnosis disease timely etiotropic therapy. Materials methods The medical histories 257 patients with treated regional infectious diseases hospital Krasnodar from 2004 2018 were analysed. data epidemiological history, clinical manifestations disease, results instrumental studies, as well principles therapy Results incidence Krai is characterised by spring-summer...

The purpose of the study improvement diagnosis and prognosis course leptospirosis on basis characteristics clinical picture pathomorphogenesis, determination main causes lethal outcomes at different stages disease, in dependence level management specialized medical care. Materials methods There were analyzed records autopsy protocols 168 patients who died from Krasnodar region 1969-2014 125 with both severe development multiple organ insufficiency. 4 groups considered: 1st -patients...

With the aim of optimization differential diagnosis there was performed an assessment cellular immunity in patients with acute viral (infectious mononucleosis associated Epstein-Barr virus) and bacterial infection (bacterial tonsillitis). Study groups consisted 22 infectious mononucleosis, comparison group - 19 tonsillitis. There revealed a number significant changes typical for process various etiology. The features terms EBV-associated are: increase cytotoxic CD8(+) T-cells; consistent...

The aim of the work was to study structure, level and dynamics resistance antimicrobial drugs most common types microorganisms in patients with community-acquired pneumonia (CAP) Krasnodar Territory, on example treated a regional specialized infectious hospital for period 2015-2017. Materials methods. results bacteriological tests expectoration, including 523 positive strains microorganisms, are analyzed. analysis does not include multidrug resistance. A bacterioscopy Gram stain sputum...

Epidemiological and clinical-laboratory features of the course drug-induced viral liver damage are considered. Clinical observation severe toxic in a patient suffering from chronic hepatitis “C” is given. The authors share experience successful therapy.

Background. Today, according to the WHO, in Russia 15% of couples do not have children. Opportunistic infections adults are pathological processes that occur and develop against background a reduced immune response often cause infertility.
 Aim. To study ratio opportunistic infection markers women with various types infertility who treated IVF create model for predicting treatment outcomes.
 Materials methods. The main sample consisted 711 patients, aged 20 46 years, were methods...

При расчете внутриквартальных участков наружной канализации специалисты отдают предпочтение нормативным документам, регламентирующим проектирование внутренних, а не уличных сетей, так как эти участки по количеству транспортируемых сточных вод и режиму водоотведения ближе к внутренним системам.Основным документом при внутренних систем был является в настоящее время СНиП 2.04.01-85 «Внутренний водопровод канализация зданий».Дополнительно с 1 января 2013 г. приказом Минрегиона РФ введен...

In a review of the literature there are considered problems hematopoiesis in HCV-infection and discussed different mechanisms anemia. On basis analysis current evidence it was shown that anemia chronic hepatitis C may have hyporegenerative character be associated with myelosuppressive effect viral infection (directly or indirectly through change cytokine profile), has features so-called diseases, regenerative as consequence blood loss, immune non-immune hemolysis, microangiopathies,...

The goal - improving the quality of diagnosis acute infectious mononucleosis (IM) in adults on basis a comparative study cytokine status MI, tonsillitis and viral hepatitis. Materials methods. We observed three groups patients hospitalized «Specialized Clinical Hospital Infectious Diseases Ministry Health Krasnodar Territory» 2012-2014: 29 with myocardial infarction (group 1), 25 2), 19 hepatitis 3) control group. were matched by sex, age severity disease. In phase disease level cytokines...

The cytokine status was studied in 46patients hospitalized Specialized Clinical Infectious Diseases Hospital 2013-2014. Acute course of the infection Ixodes tick borreliosis (ITB) observed 41 (89%) case, subacute and chronic - 5 (11%), dynamics disease there level proinflammatory (IFN-y, IL-1β, IL-2) anti-inflammatory ( IL-4, IL-10) cytokines. average age diseased patients acute erythemalform ITB amounted to 41,1 ± 1,83 years, men accouted for 37%, women 63%. In 31.1% were symptoms...