- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Bone Tissue Engineering Materials
- Additive Manufacturing and 3D Printing Technologies
- Medical and Biological Sciences
- Engineering Technology and Methodologies
- Surgical Sutures and Adhesives
- Reconstructive Surgery and Microvascular Techniques
- 3D Printing in Biomedical Research
- Organ and Tissue Transplantation Research
- Mesenchymal stem cell research
- Xenotransplantation and immune response
- Medical and Biological Ozone Research
- Advanced Battery Technologies Research
- Structural mechanics and materials
- Reconstructive Facial Surgery Techniques
- Collagen: Extraction and Characterization
- Hepatitis C virus research
- Technology and Human Factors in Education and Health
- Engineering and Agricultural Innovations
- Myofascial pain diagnosis and treatment
- Advanced Computational Techniques in Science and Engineering
- Abdominal vascular conditions and treatments
- Hemostasis and retained surgical items
Kuban State Medical University
2014-2023
Ministry of Health of the Russian Federation
2017-2021
Sechenov University
2017
Kuban State University
2017
Federal State Budgetary Scientific Institution Research Institute of Medical Primatology
2016
Karolinska Institutet
2013-2016
Specialized Clinical Psychiatric Hospital No. 1
2013
Abstract A tissue-engineered oesophageal scaffold could be very useful for the treatment of pediatric and adult patients with benign or malignant diseases such as carcinomas, trauma congenital malformations. Here we decellularize rat oesophagi inside a perfusion bioreactor to create biocompatible biological scaffolds that mimic native architecture, resist mechanical stress induce angiogenesis. Seeded allogeneic mesenchymal stromal cells spontaneously differentiate (proven by gene-, protein...
Background . Wounds of various aetiology are among the most frequent traumatic injuries. A prospective route to improve treatment this nosology is development novel or advancement already on-stage dressing materials. Objectives. comparative experimental assay chitosan-based wound dressings in healing soft tissue wounds different genesis using ultrasound control biodegradation developed dosage form. Methods. Soft were modelled animals, conventional and lineage male rats, 275 (± 25) g body...
Aim. The main aim of our research is to evaluate the process rat lung decellularization and recellularization as initial step tissue-engineered organs creation. Materials methods. Rat was performed by perfusion with detergents enzymes concomitant atmospheric air ventilation through trachea. quality analyzed routine histological immunohistochemical staining techniques, DNA content determined quantitatively spectrophotometer. For static whole organ reseeding a model cells’ behavior mesenchymal...
The purpose of research - based on analysis the clinical-epidemiologic data, level viral load and prevalence HCV genotypes to determine current consistencies epidemiological trends development HCV-infection in area Krasnodar Territory. Patients methods. Population incidence hepatitis C Territory was studied for period from 2004 2011. Clinical manifestations disease we evaluated base a retrospective 1913 hospital records patients with chronic C. There were investigated results 19,338...
of concern on the manuscript 'Experimental orthotopic transplantation a tissue-engineered oesophagus in rats' from Sjo ¨qvist et al. to alert our readership concerns regarding integrity study.An investigation related this research has been conducted by Expert Group for Misconduct Research at Swedish Central Ethical Review Board behalf Karolinska Institutet.A statement summarizing results...
Despite a significant range of therapeutic measures employed to treat inflammatory diseases in the maxillofacial area, much effort falls short effective suppression infection and proper regeneration as outcome pathological process [1][2][3][4][5][6].The development optimal wound covering that would contribute fast complete recovery damaged structures appears an urgent issue modern medicine.Scientific items, monographs patents offer wide materials used create covering, with over 400 various...
Aim. To carry out a quantitative immunophenotypic characterisation of cellular corporations in mononuclear inflammatory myocardial infiltrate the cell and humoral forms heart transplant rejection using computer morphometry endomyocardial biopsy samples. Materials methods. Endomyocardial samples (n = 226) were obtained from 56 recipients who underwent transplantation 2018–2019. Sections with thickness 5 μm after paraffin infiltration stained hematoxylin eosin according to standard procedure....
ХАРАКТЕР ЭКСПРЕССИИ C-FOS НЕЙРОНАМИ МЕДИАЛЬНОЙ ПРЕФРОНТАЛЬНОЙ КОРЫ В
Automated image analysis methods are highly important for biotechnology research. The authors developed and tested a program the morphometric of photomicrographs sections processed using standard immunohistochemical examination protocols. color deconvolution method used in algorithm was proven to be effective mapping distribution DAB chromogen sample containing multiple dyes. experiment demonstrated that level extracellular matrix proteins could comparatively quantified different groups...
Экспериментальная медицинаT issue engineering is one of the branches regenerative medicine that may offer an alternative treatment option for patients in need organ transplantation.The main point tissue restoring structural and functional intactness tissues organs using bioartificial constructions, which include following [3]:-Cells able to create functioning extracellular matrix.-Suitable biodegradable scaffold (matrix) cells transplantation.
A rapidly growing development of tissue engineering promotes the increasing interest in obtainment various decellularizedtissues and organs. Minimal quality evaluation criteria obtained engineered constructions have been previously specified. In discussionpaper group authors considers morphological methods matrix applied by researchers on model heart decellularization. The analysis modern literature authors’ own researches shown that decellularization has to be complex should consist several...