A5005807553- Cervical Cancer and HPV Research
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Estrogen and related hormone effects
- Reproductive Health and Contraception
- Maternal and Perinatal Health Interventions
- Cancer Genomics and Diagnostics
- Ectopic Pregnancy Diagnosis and Management
- Maternal and fetal healthcare
- Genetic factors in colorectal cancer
- Cardiac, Anesthesia and Surgical Outcomes
- Genital Health and Disease
- Anesthesia and Pain Management
- Hepatitis B Virus Studies
- Reproductive tract infections research
- Menopause: Health Impacts and Treatments
- Epigenetics and DNA Methylation
- Pregnancy-related medical research
- Pregnancy and preeclampsia studies
- TGF-β signaling in diseases
- Airway Management and Intubation Techniques
- Preterm Birth and Chorioamnionitis
- Medical History and Innovations
- Sarcoma Diagnosis and Treatment
- Mathematical Biology Tumor Growth
Haukeland University Hospital
2003-2022
University of Bergen
1987-2022
Cancer Registry of Norway
2009
Norwegian Institute of Public Health
2009
Weatherford College
2009
Institute of Clinical Research
2007
Skedsmo Medisinske Senter
2005
University of Oxford
1997
St Olav's University Hospital
1994
Smerteklinikken
1991
Objectives To evaluate the prophylactic efficacy of human papillomavirus (HPV) quadrivalent vaccine in preventing low grade cervical, vulvar, and vaginal intraepithelial neoplasias anogenital warts (condyloma acuminata).
Hormone replacement therapy (HT) is known to increase the risk of breast cancer in healthy women, but its effect on survivors less clear. The randomized HABITS study, which compared HT for menopausal symptoms with best management without hormones among women previously treated cancer, was stopped early due suspicions an increased new events following HT. We present results after extended follow-up. a randomized, non–placebo-controlled noninferiority trial that aimed be at power 80% detect...
<b>Objectives</b> To examine the consequences of cervical conisation in terms adverse outcome subsequent pregnancies. <b>Design</b> Population based cohort study. <b>Data sources</b> Data on derived from Cancer Registry Norway and pregnancy Medical Birth Norway, 1967-2003. 15 108 births occurred women who had previously undergone 57 136 subsequently underwent conisation. In same period there were 2 164 006 to not relevant treatment (control). <b>Results</b> The proportion preterm delivery...
PURPOSE: For endometrial carcinoma patients, there is a need for improved identification of high-risk groups that may benefit from postoperative adjuvant therapy. We therefore studied the prognostic impact markers cell proliferation, cell-cycle regulation, and angiogenesis among patients in population-based setting. PATIENTS AND METHODS: All diagnosed with between 1981 1985 Hordaland County, Norway, were studied. The median follow-up survivors was 11.5 years (range, 8 to 15 years), no...
Ovarian cancer spreads intraperitoneally and forms fluid, whereby the diagnosis therapy often become delayed. As complement (C) system may provide a cytotoxic effector arm for both immunological surveillance mAb-therapy, we have characterised C in intraperitoneal ascitic fluid (AF) from ovarian patients. Most of AF samples showed alternative classical pathway haemolytic activity. The levels C3 C4 were similar to or lower normal range when compared values sera, respectively. However, elevated...
The aim of the study was to find incidence and clinical implications peripartum hysterectomy in our department identify women at risk improve treatment before resorting hysterectomy.In period 1981-1996, cases with among a total 70,546 deliveries were identified from three different sources. variables obtained by review maternal records.In period, 11 cases, representing an 0.2 hysterectomies per 1000 found. Eight had cesarean section spontaneous vaginal delivery. Six patients previous...
Objectives. Medical abortion was first introduced in Norway April 1998. The aims of this study were to assess the efficacy, side effects, and acceptability medical using mifepristone orally misoprostol vaginally a Norwegian population. Design. included 226 pregnant women with gestational age <63 days who requested nonsurgical during year hospital regimen. Methods. All received single dose 600 mg orally, followed at 48 hours by 800 μg vaginally. Treatment outcome complications principal...
Newborn screening for total homocysteine (tHcy) in blood may identify babies with vitamin B12 (B12) deficiency or homocystinuria, but data on the causes of increased tHcy samples are sparse.Serum concentrations tHcy, cystathionine, methionine, folate, and methylenetetrahydrofolate reductase (MTHFR) 677C > T polymorphism were determined 4992 capillary collected as part routine program newborn children. Methylmalonic acid (MMA), gender (SRY genotyping), frequency six cystathionine...
Biodegradable pins of polyglycolic acid (PGA) or polylactic (PLA) have been used in the treatment fractures and osteotomies during past 5 years. Adverse effects reported included swelling at implantation site sinus formation, considered to represent nonspecific foreign-body reactions. Recent reports, however, shown severe reactions after intraarticular fracture fixation. Reactions 2 patients, treated with for osteochondritis dissecans (OCD) our hospital, prompted present clinical...
To evaluate the acceptability and efficacy of medical abortion at home up to 63 days' gestation without limits on travel distance a registered institution.
Objective To identify women treated for endometrial carcinoma with increased risk recurrent disease, to examine how and when recurrences are discovered, assess the clinical benefit of routine follow up investigations. Design Retrospective case analysis. Setting Hordaland county, Norway. Population All in a demographically well defined area, 10‐year period (1981–1990). Methods Data concerning patient characteristics course disease were collected through review medical records, correspondence...
Abstract Background: Cervical cancer screening programs are facing a programmatic shift where protocol based on human papillomavirus testing (HPV-Screening protocol) is replacing the liquid-based cytology (LBC-Screening protocol). For safe technology transfer within nationwide programme in Norway, HPV-Screening was implemented randomized to compare real-world effectiveness of and LBC-Screening at first round. Methods: Among 302,295 women ages 34 69 years scheduled attend from February 2015...
Objective.To determine the incidence and complications related to manual removal of placenta.Methods.Review hospital medical records from 1990 throughout 1994.One thousand five hundred two vaginal deliveries 1984-1992 were used for comparisons.Results.A total 24,750 registered during year study period.Placenta was removed manually in 165 women (0.6%).The use general anesthesia placenta decreased 74% 19% 1994.Spinal analgesia applied 1993, it 42% 1994.Of 74 parous women, 12 (16%) had...
BACKGROUND Several epidemiologic studies have shown an inverse relationship between parity and the incidence of endometrial carcinoma. A prognostic influence reproductive factors has been reported for carcinomas breast uterine cervix; but no such independent carcinoma, to authors' knowledge. Therefore, authors investigated importance in unselected group patients. METHODS Clinical histopathologic data on all 316 patients treated carcinoma during period 1981-1990 Hordaland County, Norway, were...
Prognostic factors for outcome of malignant disease should be based on objective assessments whenever possible, so that the results may reproduced. In a prospective study, tumor samples from 75 patients were subjected to flow cytometric DNA analysis. Samples also taken 61 estradiol and progesterone receptor measurements. The course was analysed with regard ploidy status. Receptor status significantly correlated ploidy, as diploid tumors more often receptor‐positive or receptor‐rich (≥30...
Abstract Control of technique and use biological standards in flow cytometry have become increasingly important due to the wider method for ploidy determination malignant tumors clinical research. Trout (TRBC) salmon erythrocytes human buffy coat leukocytes were selected a study factors influencing DNA stainability. Whether standard test cells mixed before or after enzymatic treatment staining was found be critical comparisons. Otherwise, artifactual differences at least 20% may noted,...