A5001711102- RNA modifications and cancer
- Molecular Biology Techniques and Applications
- RNA Research and Splicing
- Advanced Proteomics Techniques and Applications
- Bioinformatics and Genomic Networks
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Genomics and Phylogenetic Studies
- Machine Learning in Bioinformatics
- Adipokines, Inflammation, and Metabolic Diseases
Baker Heart and Diabetes Institute
2023
Institute of Bioinformatics
2016-2018
Amrita Vishwa Vidyapeetham
2018
Narayana Health
2017
Splice variants are known to be important in the pathophysiology of tumors, including brain cancers. We applied a proteogenomics pipeline identify splice glioblastoma (GBM, grade IV glioma), highly malignant tumor, using in-house generated mass spectrometric proteomic data and public domain RNASeq dataset. Our analysis led identification novel exon that maps long isoform Neural cell adhesion molecule 1 (NCAM1), expressed on surface glial cells neurons, for signaling. The presence is...