A5044751577- Toxin Mechanisms and Immunotoxins
- Bioactive Compounds and Antitumor Agents
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Phytochemistry and Bioactive Compounds
- Paleopathology and ancient diseases
- Immune Cell Function and Interaction
- Marine Sponges and Natural Products
- Phytochemical compounds biological activities
- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Chronic Lymphocytic Leukemia Research
Universidade Estadual Paulista (Unesp)
2009-2021
Centro Universitário de Araraquara
2011
Universidade de Fortaleza
2010
PURPOSE: To compare chemical to morphological kidney stone composition analysis based on a sample of 50 stones retrieved from patients at nephrology service. METHODS: The was performed with Bioclin® kit, while 10-mm magnifying glass (10x; Prolabo, Paris, France) employed in the analysis. Findings obtained two methods were compared and classified as concordant (100% agreement), partly (concordant for major components, discordant minor components) or (discordant components). RESULTS: In...
1 The purpose of the present study was to investigate antitumour and anti-inflammatory activities flavonoids isolated from Byrsonima crassa, Davilla elliptica Mouriri pusa. activity measured by MTT assay in murine mammary tumour cells (LM2) IC 50 values fl avonoids tested ranged (31.5 ± 2.97) (203.1 5.9) μg/ml. (myricetin-3-O-α-L-rhamnopyranoside) 3 (quercetin-3-Ogalactopyranoside) D. were most active ones against cells. same samples determine inhibition release nitric oxide (NO) necrosis...
Abstract Background Ribosome-inactivating proteins (RIP) have been studied in the search for toxins that could be used as immunotoxins cancer treatment. Pulchellin, a type 2 RIP, is suggested to induce immune responses role controlling cancer. Methods The percentage of dendritic cells and CD4 + CD8 T spleen (flow cytometry), cytokines’ release by PECs splenocytes (ELISA) nitric oxide production (Griess assay) were determined from tumor-bearing mice injected intratumorally with 0.1 ml...
This work describes a pharmacological screening of Brazilian medicinal plants through their anti-inflammatory and cytotoxicity activities. Cytotoxicity activity Mouriri elliptica Alchornea glandulosa as well the drugs celecoxib doxorubicin were evaluated in cultures peritoneal macrophages. The immune system influence these samples was analyzed by determining production/inhibition NO, production tumor necrosis factor-α interleukin-10. Regarding there NO M. inhibition when cells exposed to A....