- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Gastroesophageal reflux and treatments
- Clinical Nutrition and Gastroenterology
- Eosinophilic Esophagitis
- Microscopic Colitis
- Hepatocellular Carcinoma Treatment and Prognosis
- Helicobacter pylori-related gastroenterology studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatitis C virus research
- Inflammatory Bowel Disease
- Diverticular Disease and Complications
- Gastrointestinal disorders and treatments
- Viral-associated cancers and disorders
- Sirtuins and Resveratrol in Medicine
- Genomics, phytochemicals, and oxidative stress
- Healthcare cost, quality, practices
- Myasthenia Gravis and Thymoma
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Screening and Detection
- Hepatitis B Virus Studies
- Gastric Cancer Management and Outcomes
- Organ Transplantation Techniques and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Gastrointestinal Tumor Research and Treatment
Tufts University
2020
Tufts Medical Center
2018-2019
MetroHealth Medical Center
2014-2018
Case Western Reserve University
2014-2018
MetroHealth
2016-2017
Cleveland Clinic
2012-2015
University of Iowa Hospitals and Clinics
2015
Creative Research Enterprises (United States)
2015
Northeast Ohio Medical University
2010-2011
Ohio University
2010-2011
OBJECTIVES: Optimal administration of proton pump inhibitor (PPI) for the treatment gastroesophageal reflux disease (GERD) requires consideration meal timing. Since becoming available over counter (OTC), no studies have assessed patterns and symptom control in OTC consumers. The objective this study was to survey dosing prescription PPI users. METHODS: Patients at five clinics were surveyed regarding diagnosis GERD, use or PPIs, information on time day dosing, demographics, Gastroesophageal...
Abstract Introduction Recurrent hepatocellular carcinoma ( HCC ) following liver transplantation LT carries a poor prognosis. The aim of our study was to assess the safety and efficacy sorafenib in patients with recurrent . Methods A prospectively maintained database retrospectively analyzed for between 2001 2011–34 patients. Patients were divided into two groups based on whether they prescribed (n = 17) or not 17). primary endpoint overall survival. Results There no significant differences...
Hepatocellular carcinoma (HCC), one of the most common and lethal cancers, is a growing menace in modern society. Until recently, majority detected cases liver cancer have been found developing nations Asia Africa; however, its occurrence has significantly increased United States. HCC occurs due to several etiologies, such as alcoholism, dietary carcinogens, iron overload, viral hepatitis, well hepatic chronic diseases. In view limited treatment options, surgery transplantation, critical...
Background and aims: Hilar cholangiocarcinoma is a devastating malignancy with incidence varying by geography other risk factors. Rapid progression of disease delays in diagnosis restrict the number patients eligible for curative therapy. The objective this study was to determine prognostic factors overall survival all presenting hilar cholangiocarcinoma. Methods: All adult histologically confirmed from 2003 2013 were evaluated predictors using demographic factors, laboratory data, symptoms...
Colorectal cancer (CRC) is a common form of malignancy and leading cause death in the United States. Screening decreases CRC incidence mortality. African Americans are at an increased risk developing CRC, recommendations to initiate screening age 45. This study aims assess rate for colorectal between ages 45-49.African 45-49 were identified Explorys national database. Patients who completed colonoscopy, sigmoidoscopy or fecal occult blood test stratified by sex insurance status. A P value <...
Introduction. The progression of chronic liver disease to cirrhosis involves both innate and adaptive immune system dysfunction resulting in increased risk infectious complications. Vaccinations against pneumococcus, hepatitis A virus (HAV), B (HBV) are well tolerated effective prevention reduction morbidity mortality. Prior studies assessing vaccination rates patients with have specific limitations date no study has provided a comprehensive evaluation the United States. Aim. This assessed...
Hepatocellular carcinoma (HCC), one of the most common and lethal cancers, is a growing menace in modern society. Until recently, majority detected cases liver cancer have been found developing nations Asia Africa; however, its occurrence has significantly increased United States. HCC occurs due to several etiologies, such as alcoholism, dietary carcinogens, iron overload, viral hepatitis, well hepatic chronic diseases. In view limited treatment options, surgery transplantation, critical...
Key Clinical Message Small bowel intussusception is a relatively uncommon cause of abdominal pain. The diagnosis often delayed due to vague symptoms and limitations with current endoscopic radiographic approaches evaluate the small lumen. Treatment requires surgical resection, which can usually be performed in minimally invasive fashion.
Bile salt export pump (BSEP) is the principal exporter of bile salts (BiS) from hepatocyte cytoplasm.It expressed at canalicular / apical aspect hepatocytes and well-differentiated (WD) hepatocellular carcinoma (HCC) cells.Immunohistochemically demonstrable BSEP expression (IDBE) begins in early second trimester.WD epithelial hepatoblastoma (HB) cells resemble relatively mature, polarised hepatocytes.They lack IDBE.Absence IDBE associated with cytoplasmic rarefaction, cholestasis,...
Abstract Hepatocellular carcinoma (HCC), one of the most common and deadliest malignancies in world, has been increasing steadily Japan, Europe as well United States. HCC develops frequently background oxidative stress chronic unresolved hepatic inflammation due to viral infection, alcoholic cirrhosis exposure several environmental carcinogens. In absence proven effective systemic therapy for HCC, novel chemopreventive strategies are urgently needed lower current morbidity mortality...
Background: Weather patterns are well-known to affect human health and behavior often arbitrarily blamed for high no-show rates (NSRs). The NSR outpatient gastrointestinal procedures ranges from 4% 41% depending on the population procedure performed. Identifying potential causes will allow optimization of endoscopy resource utilization. Aim: aim this study was evaluate effects a day year weather conditions have NSRs endoscopic at safety-net hospital in Cleveland, Ohio, United States....