Matthew Lynch

ORCID: 0000-0002-5112-7816
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About
Contact & Profiles
Research Areas
  • Dialysis and Renal Disease Management
  • Pharmaceutical Practices and Patient Outcomes
  • Innovations in Medical Education
  • Muscle and Compartmental Disorders
  • Healthcare Quality and Management
  • Autophagy in Disease and Therapy
  • Renal function and acid-base balance
  • Medical Malpractice and Liability Issues
  • Patient Safety and Medication Errors
  • Kidney Stones and Urolithiasis Treatments
  • Pediatric Urology and Nephrology Studies
  • Potassium and Related Disorders
  • COVID-19 Digital Contact Tracing
  • Antibiotic Use and Resistance
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Childhood Cancer Survivors' Quality of Life
  • Sirtuins and Resveratrol in Medicine
  • Environmental Education and Sustainability
  • Maternal and fetal healthcare
  • PARP inhibition in cancer therapy
  • Child and Adolescent Psychosocial and Emotional Development
  • Climate Change Communication and Perception
  • Chronic Kidney Disease and Diabetes
  • Healthcare cost, quality, practices
  • Adipose Tissue and Metabolism

Royal College of Surgeons in Ireland
2019-2024

Brown University
2019-2023

Rhode Island Hospital
2020-2022

Beth Israel Deaconess Medical Center
2017-2019

Harvard University
2017-2019

University of Technology Sydney
2018

University College Cork
1998

Cork University Hospital
1998

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread around the world. As of end June 2021, there were approximately 181 million confirmed cases and more than 3.9 deaths across globe. The colossal impact disease 2019 (COVID-19) is driving biggest vaccination campaign in human history. All 3 vaccines authorized for emergency use by US Food Drug Administration (Pfizer-BioNTech, Moderna, Janssen/Johnson & Johnson) have been thoroughly studied found be safe effective...

10.1053/j.ajkd.2021.06.016 article EN other-oa American Journal of Kidney Diseases 2021-07-17

Because injured mitochondria can accelerate cell death through the elaboration of oxidative free radicals and other mediators, it is striking that proliferator γ coactivator 1-α (PGC1α), a stimulator increased mitochondrial abundance, protects stressed renal cells instead potentiating injury. Here, we report PGC1α's induction lysosomes via transcription factor EB (TFEB) may be pivotal for kidney protection. CRISPR stable gene transfer showed PGC1α-KO tubular were sensitized to genotoxic...

10.1172/jci.insight.126749 article EN JCI Insight 2019-03-14

Shortages in healthcare workers affects the overall delivery and effectiveness of provision healthcare. There are currently insufficient pharmacists working community sector Ireland. While several studies have reported on factors leading to retention medical nursing profession, there is an absence robust research examining within pharmacist workforce Ireland.To identify understand range at play pharmacy Ireland which influence decision-making process for deciding whether or not continue...

10.1016/j.rcsop.2023.100329 article EN cc-by-nc-nd Exploratory Research in Clinical and Social Pharmacy 2023-09-09

“Colleges and universities can only thrive if society the biosphere are healthy. Any institution that is so shortsighted as to pursue its ends without taking into account interests of larger community or ecosystem in which it enmeshed will not achieve sustainable success. In end, find itself forced, one way another, deal with fact future linked web social ecological relations” (Bardaglio & Putman, 2009, p. 174). “You mature enough tell like is. Even burden you leave us children” (Thunberg, 2018).

10.54656/iowf3526 article EN cc-by Journal of Community Engagement and Scholarship 2021-01-01

The recent recommendation by the American Society of Nephrology/National Kidney Foundation task force to immediately eliminate "race" factor in estimated glomerular filtration rate (eGFR) equation (1) is a much-needed and long-overdue correction original Modification Diet Renal Disease (MDRD) Chronic Epidemiology Collaboration (CKD-EPI) eGFR equations. While primary continual goal MDRD, CKD-EPI, other equations has been agree with measured GFR (mGFR), we believe this was misguided as shown...

10.1093/jalm/jfac001 article EN The Journal of Applied Laboratory Medicine 2022-01-11

Reforms to models of health and care regulation internationally have adapted address the challenges associated with regulating healthcare professionals. Pharmacists in Ireland entered a new era enactment Pharmacy Act 2007 which significantly updated law pharmacy expanded regulatory scope considerably. An earlier study 2017 examined experiences 20 community pharmacists Act. This follow-up aimed expand original all Ireland, report their "lived experience" model introduced by Act, assessing its...

10.1186/s40545-022-00465-5 article EN cc-by Journal of Pharmaceutical Policy and Practice 2022-10-29

Three Higher Education Institutions (HEIs) in Ireland are accredited to provide education and training, successful completion of which, entitles one register as a pharmacist with the Pharmaceutical Society (PSI). Legislation (2014) mandated that these HEIs replace their existing structure (four-year degree followed by one-year internship), five-year 'integrated Master's programme'. Integration includes 'in-service practical training' (placement) at beginning Year 4 (four months), end 5...

10.3390/pharmacy7030093 article EN cc-by Pharmacy 2019-07-16

With increasing prevalence of both kidney disease and cancer, patients who have are common. Toxicity from treatment or direct injury by the cancer itself can lead to acute progression pre-existing chronic disease. Management advanced end-stage among those with concomitant is challenging; however, better understanding complications in this population will allow for optimization treatments. Strategies medication dosing, judicious use erythropoiesis-stimulating agents anemia, options mineral...

10.1177/2399369320918256 article EN Journal of Onco-Nephrology 2020-02-01

Figure S1 Individual patient potassium values by dialysis session. Table S1. Serum chemistries timepoint. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied authors. Any queries (other than missing content) should be directed to corresponding author article.

10.1111/hdi.12897 article EN Hemodialysis International 2020-10-22
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