Wei Cai

ORCID: 0000-0002-5138-7319
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Research Areas
  • Metal-Organic Frameworks: Synthesis and Applications
  • Magnetism in coordination complexes
  • Nanowire Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Memory and Neural Mechanisms
  • Nanocluster Synthesis and Applications
  • Metal Extraction and Bioleaching
  • Neuroscience and Neuropharmacology Research
  • Iron and Steelmaking Processes
  • Gas Sensing Nanomaterials and Sensors
  • Neural dynamics and brain function
  • Fire Detection and Safety Systems
  • Advanced Photocatalysis Techniques
  • Connexins and lens biology
  • Molecular Sensors and Ion Detection
  • Covalent Organic Framework Applications
  • Calpain Protease Function and Regulation
  • Icing and De-icing Technologies
  • Chemical Looping and Thermochemical Processes
  • Surface Modification and Superhydrophobicity
  • Cardiovascular Disease and Adiposity
  • Neuropeptides and Animal Physiology
  • Thermoregulation and physiological responses
  • Neuroendocrine regulation and behavior
  • Congenital heart defects research

Xi'an Polytechnic University
2022-2024

Dalian University
2021-2022

Dalian University of Technology
2021-2022

State Key Laboratory of Medical Neurobiology
2013-2021

Fudan University
2013-2021

Institute of Neurobiology
2021

Central South University
2005-2020

GlaxoSmithKline (China)
2018

GlaxoSmithKline (United Kingdom)
2018

Huazhong University of Science and Technology
2013

The prefrontal cortex (PFC) plays a critical role in cognitive functions, including working memory, attention regulation, behavioral inhibition, as well memory storage. functions of PFC are very sensitive to norepinephrine (NE), and even low levels endogenously released NE exert dramatic influence on the functioning PFC. Activation β-adrenoceptors (β-ARs) facilitates synaptic potentiation enhances hippocampus. However, little is known regarding these processes In present study, we...

10.1101/lm.030411.113 article EN Learning & Memory 2013-04-17

Metal-organic frameworks (MOFs) have gained attention as multifunctional catalytic platforms, allowing us to gain important insights into synergistically activating both C-H bonds and oxygen for improving oxidation. Herein, by ingenious incorporation of anthraquinone, we report an anthraquinone-based MOF a bifunctional heterogeneous photocatalytic platform simultaneously activate inert C(sp3)-H bond Making use the rigid framework with fixation isolation effect, great chemical stability...

10.1021/acs.inorgchem.2c00441 article EN Inorganic Chemistry 2022-06-13

Abstract The activation and oxidization of inert C(sp 3 )−H bonds into value‐added chemicals affords attractively economic ecological benefits as well central challenge in modern chemistry. Inspired by the natural enzymatic transformation, herein, we report a new multiphoton excitation approach to activate oxygen integrating photoinduced electron transfer (PET), ligand‐to‐metal charge (LMCT) hydrogen atom (HAT) events together one metal ‐ organic framework. well‐modified nicotinamide adenine...

10.1002/anie.202114490 article EN Angewandte Chemie International Edition 2021-11-08

Xanthene dyes as a class of ideal organic homogeneous photocatalyst have received significant attention in C-H bond activation; however, the inherent nature fast carrier recombination/deactivation and low stability limits their practical applications. Herein, by ingenious decoration eosin Y into porous metal-organic framework (MOF), high-performance heterogeneous MOF-based was prepared to efficiently activate inert bonds on reactants via hydrogen atom transfer pathway for functionalization...

10.1021/acs.inorgchem.1c03813 article EN Inorganic Chemistry 2022-05-04

Little is known about the impact of blood–nerve barrier (BNB) on drug distribution into peripheral nerves. In this study, we examined nerve penetration in rats 11 small-molecule drugs possessing diverse physicochemical and transport properties ProTx-II, a tarantula venom peptide with molecular mass 3826 Daltons. Each was administered as constant rate intravenous infusion for 6 hours (small molecules) or 24 (ProTx-II). Blood tissues including brain, spinal cord, sciatic nerve, dorsal root...

10.1124/jpet.117.245613 article EN Journal of Pharmacology and Experimental Therapeutics 2018-03-06

ABSTRACT Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are widely expressed in neurons the central nervous system. It has been documented that HCN regulate intrinsic excitability of pyramidal cells medial prefrontal cortex (mPFC) rodents. Here, we report limited GABAergic transmission onto rat mPFC. The pharmacological blockade resulted a significant increase frequency both spontaneous and miniature inhibitory postsynaptic currents (IPSCs) mPFC cells, whereas...

10.1242/bio.058840 article EN cc-by Biology Open 2021-10-28

Abstract The number and subtype composition of N-methyl-d-aspartate receptor (NMDAR) at synapses determines their functional properties role in learning memory. Genetically increased or decreased amount GluN2B affects hippocampus-dependent memory the adult brain. But some experimental conditions (e.g., elicited by a single conditioning trial (1 CS-US)), is not necessary factor, which indicates that precise formation requires further exploration. Here, we examined consolidation fear using two...

10.1038/srep30743 article EN cc-by Scientific Reports 2016-08-04

To observe the effects of fructose-1,6-diphosphate (FDP) on serum levels cardiac troponin I (cTnI) and creatine kinase-MB (CK-MB), as well concentration calcium in cardiomyocytes (Myo[Ca(2+)]) activity sarcoplosnic Ca(2+)-ATPase (SRCa(2+)-ATPase) Adriamycin (ADR)-treated rats.Rats were intraperitoneally injected with ADR (2.5 mg/kg every other day for 6 times) then different dosages FDP (every twenty-one times). Bi-antibodies sandwich Enzyme linked immune absorption assay (ELISA) was...

10.1631/jzus.2005.b0622 article EN Journal of Zhejiang University SCIENCE A 2005-06-22

With the gradual depletion of high grade iron ores, effective utilization low ore resources is currently a subject concern.][3][4][5][6][7] However, such still cannot be well utilized due to complex mineralogy, fine mineral particles (average size ≤0.045mm).Effective these great benefits ironmaking and steelmaking industry in areas.Banded hematite quartzite (TFe 41.8 wt%, SiO 2 41.25 wt%) was treated by flotation, TFe concentrates recovery were 64 wt% 67% respectively. 3)However, raw should...

10.2355/isijinternational.isijint-2019-381 article EN cc-by-nc-nd ISIJ International 2020-04-15

Abstract The activation and oxidization of inert C(sp 3 )−H bonds into value‐added chemicals affords attractively economic ecological benefits as well central challenge in modern chemistry. Inspired by the natural enzymatic transformation, herein, we report a new multiphoton excitation approach to activate oxygen integrating photoinduced electron transfer (PET), ligand‐to‐metal charge (LMCT) hydrogen atom (HAT) events together one metal ‐ organic framework. well‐modified nicotinamide adenine...

10.1002/ange.202114490 article EN Angewandte Chemie 2021-11-08

10.1631/jzus.2006.b0648 article EN Journal of Zhejiang University SCIENCE B 2006-07-17

Aim: to investigate effects of Losartan on expression connexin 40 and 43 (Cx40 Cx43), in arteries at the early stage atherosclerosis a rabbit model.Methods: A total 28 male New Zealand white rabbits were divided into following groups: control group, high fat diet group (10 mg/kg/day).Losartan was administrated food for two weeks.Iliac obtained immunohistochemistry, transmission electron microscopy, Western blot, reverse transcriptase-polymerase chain reaction (RT-PCR).Results: Transmission...

10.7150/ijms.7.82 article EN cc-by-nc International Journal of Medical Sciences 2010-01-01

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10.2139/ssrn.4770201 preprint EN 2024-01-01

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10.2139/ssrn.4781166 preprint EN 2024-01-01

Afterburning of a rich exhaust/air mixture ahead the catalyst has been shown in earlier papers to offer an effective means achieving light-off very short times. Protection from overheating is important aspect systems using EGI, and on board diagnostics will be required check for proper function EGI. In this paper, some options these requirements are discussed, high temperature linear thermistor. (A) For covering abstract see IRRD 858138.

10.4271/930938 article EN SAE technical papers on CD-ROM/SAE technical paper series 1993-03-01

10.4271/922248 article EN SAE technical papers on CD-ROM/SAE technical paper series 1992-10-01

To observe the effect of Yangxueqingnao particles on rat vascular smooth muscle cell (VSMC) proliferation induced by lysophosphatidic acid (LPA).The amount (3)H-TdR ((3)H-thymidine) admixed in cultured VSMC was measured and mitogen-activated protein kinase (MAPK) activity lipid peroxidation end product malondialdehyde (MDA) content were assayed.1x10(-9), 1x10(-8), 1x10(-7) mol/L LPA a concentration dependent manner, admixed, MAP activity, MDA to increase. However, 5%, 10%, 15% serum...

10.1631/jzus.2005.b0892 article EN Journal of Zhejiang University SCIENCE A 2005-08-30

Two novel Ni/Co-MOFs electrocatalysts were synthesized. Ni-MOF demonstrated a good activity in electrocatalytic OER performances and short-term electrochemical durability.

10.1039/d2nj03815c article EN New Journal of Chemistry 2022-01-01
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