A5087320270- Fatty Acid Research and Health
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Eicosanoids and Hypertension Pharmacology
- Cholesterol and Lipid Metabolism
- Diet, Metabolism, and Disease
- Antioxidant Activity and Oxidative Stress
- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Food composition and properties
- Advanced Glycation End Products research
- Mitochondrial Function and Pathology
- Metabolomics and Mass Spectrometry Studies
- Clinical Nutrition and Gastroenterology
- Peroxisome Proliferator-Activated Receptors
- Lipid metabolism and biosynthesis
- Meat and Animal Product Quality
- Biochemical effects in animals
- Biochemical Analysis and Sensing Techniques
- Edible Oils Quality and Analysis
- Moringa oleifera research and applications
- Inflammatory mediators and NSAID effects
- Lipid Membrane Structure and Behavior
- Nitric Oxide and Endothelin Effects
- Muscle metabolism and nutrition
CSIRO Health and Biosecurity
2011-2025
Commonwealth Scientific and Industrial Research Organisation
2009-2023
Health Sciences and Nutrition
2002-2023
Animal, Food and Health Sciences
2010-2015
Food & Nutrition
2015
Cambridge University Press
2011
New York University Press
2011
Weatherford College
2007
Universiti Putra Malaysia
2002
MRC Epidemiology Unit
1989
The fatty-acid composition of rat heart phospholipids was examined after long-term, i.e. more than 12 months, feeding diets supplemented with n-6 fatty acids as sunflower seed oil (SSO), or n-3 tuna fish (TFO) which is a particularly rich source docosahexenoic acid (DHA). Although some small changes occurred in the relative proportions palmitic and stearic ratio total saturates to unsaturates, most important were 18:2 20:4 20:5 22:6 n-3. In general, n-6/n-3 phosphatidylcholine (PC),...
Waste from agricultural products represents a disposal liability, which needs to be addressed. Palm oil is the most widely traded edible globally, and its production generates 85 million tons of aqueous by-products annually. This stream rich in phenolic antioxidants, were investigated for their composition potential vitro biological activity. We have identified three isomers caffeoylshikimic acid as major components palm phenolics (OPP). The 2,2-diphenyl-1-picrylhydrazyl assay confirmed...
Metabolic dysfunction and hepatic abnormalities, such as those associated with high-fat, high-fructose (HFHFr) diets, are major contributors to obesity-related health issues. The growing interest in sustainable dietary interventions has highlighted the potential of plant-based byproducts. Dragon fruit (Hylocereus undatus) peel waste, rich bioactive compounds fibers, phenolics, betacyanins, represents a promising functional ingredient for managing these disorders. This study investigated...
Twelve edible plant extracts rich in polyphenols were screened for their potential to inhibit oxidation of low-density lipoprotein (LDL) vitro and modulate LDL receptor (LDLr) activity cultured HepG2 cells. The antioxidant (inhibition oxidation) was determined by measuring the formation conjugated dienes (lag time) thiobarbituric acid reagent substances (TBARS). Betel leaf (94%), cashew shoot (63%), Japanese mint (52%), semambu (50%), palm frond (41%), sweet potato shoot, chilli fruit,...
The chain length of saturated fatty acids may dictate their impact on inflammation and mitochondrial dysfunction, two pivotal players in the pathogenesis insulin resistance. However, these paradigms have only been investigated animal models cell lines so far. Thus, aim this study was to compare effect palmitic (PA) (16:0) lauric (LA) (12:0) acid human primary myotubes health metabolic inflammation. Human were challenged with either PA or LA (500 μM). After 24 h, expression interleukin 6...
A high plasma cholesterol level, especially low-density lipoprotein cholesterol, indicates increased risk of cardiovascular diseases. Plasma levels are influenced by diet and biosynthesis, uptake, secretion. Cholesterol uptake involves solubilization into complex phospholipid spherical bodies termed micelles that facilitate the transport lipids through gut brush border membrane enterocytes. In vitro assays reported to date determine potential cholesterol-lowering effects various compounds...
Male rats were fed for 3–4 months (short-term) or 12–15 (long-term) on a standard laboratory diet alone (control) supplemented with sunflower seed oil (SSO, 12 % w/w) sheep kidney fat (SKF, 12% w/w). Papillary muscles electrically driven (1 Hz, 5 ms, supramaximal voltage) at 37 °C in Krebs-Henseleit solution, and contractions measured isometrically. Both the positive inotropic responses to CA++ incidence of spontaneous tachyarrhythmias under catecholamine stress increased by short-term SKF...