<h3>Importance</h3> Perioperative respiratory adverse events (PRAEs) are the most common complication during pediatric anesthesia, and they may be affected by administration of preoperative sedatives. <h3>Objective</h3> To investigate effect intranasal dexmedetomidine or midazolam used for premedication on occurrence PRAEs. <h3>Design, Setting, Participants</h3> This single-center, double-blind, randomized clinical trial was conducted among children aged 0 to 12 years undergoing elective...

Upper gastrointestinal (UGI) cancers are highly prevalent in China and have been linked to dietary factors, yet the impact of overall diet quality remains underexplored. This study aimed assess association between Chinese quality, as measured by Diet Balance Index 2016 (DBI-16) plant-based index (PDI), UGI cancer risks high-risk populations. We conducted a prospective cohort from 2017 2019 five regions China. was assessed using DBI-16 PDI. evaluated DBI-16, which includes higher bound scores...

This study investigates the security of two-way relaying system with untrusty relay nodes. Cooperative jamming schemes are considered for bi-directional secrecy communications. The transmit power each source node is divided into two parts corresponding to user and signals, respectively. Two different assumptions signals considered. When a priori known at nodes, closed-form allocation expressions nodes derived. Under assumption unknown it proven that cooperative useless capacity, because all...

Postoperative emergence agitation/delirium (POED) is a common complication in pediatric surgery patients, which increases the risk of developing postoperative airway obstruction and respiratory depression. This study aims to investigate safety efficacy intraoperative infusion dexmedetomidine (DEX) its effects on POED patients undergoing tonsillectomy with or without adenoidectomy. Sixty scheduled for adenoidectomy, aged 2 8 years, were randomly allocated into groups (n = 30). Pediatric group...

Caffeine promotes expression of <italic>TERT</italic>, consequently increases telomere length, prevents cellular senescence and delays aging phenotypes in mice.

Abstract Background Diabetic foot ulcer (DFU) is a serious chronic complication of diabetes. This study aimed to establish weighted risk models for determining DFU occurrence and severity in diabetic patients. Methods was multi-center hospital-based cross-sectional study. A total 1488 patients with or without an from three tertiary hospitals were included the Random forest method used develop assessing severity. Receiver operating characteristic curves validate calculate optimal cut-off...

Abnormalities in glucose metabolism may be the underlying cause of β-cell dysfunction and identity impairment resulting from high exposure. In China, Coptis deltoidea C. Y. Cheng et Hsiao (YL) has demonstrated remarkable hypoglycemic effects.

Research on the imbalance of proopiomelanocortin (POMC)/agouti-related protein (AgRP) neurons in hypothalamus holds potential insights into pathophysiology diabetes. Jinkui Shenqi pills (JSP), a prevalent traditional Chinese medicine, regulate hypothalamic function and treat To investigate hypoglycemic effect JSP explore probable mechanism treating A type 2 diabetes mouse model was used to pharmacodynamics JSP. The glucose-lowering efficacy assessed through various metrics including body...

Abstract The failure of coal mine overburden is mainly caused by fractures under bending loads. energy evolution characteristics and rock are closely related to disasters such as burst. To obtain the release accumulation load, three‐point tests coal, mudstone, sandstone were carried out respectively. strength fracture propagation process load studied. strain rules calculated obtained. mechanism was discussed analyzing critical rate. results show that complexity mudstone greater than coal....

To develop a risk prediction nomogram of postoperative sleep disturbance (PSD) in patients undergoing non-cardiac surgery.Data on 881 consecutive who underwent surgery at the Affiliated Hospital Xuzhou Medical University between June 2020 and April 2021 were prospectively collected. Of these, we randomly divided into two groups, training cohort (n = 617) validation 264) ratio 7:3. Characteristic variables selected based data through least absolute shrinkage selection operator (LASSO)...

Abstract Background Diabetic kidney disease (DKD) is a severe complication of diabetes. Currently, no effective measures are available to reduce the risk DKD progression. This study aimed establish weighted model determine progression and provide treatment strategies. Methods was hospital-based, cross-sectional study. A total 1104 patients with were included in this The random forest method used develop models assess Receiver operating characteristic curves validate calculate optimal cutoff...

Prediabetes is prevalent and significantly increases lifetime risk of progression to type 2 diabetes mellitus (T2DM). Acupuncture has been increasingly used for prediabetes in China but its effect unclear. We aim assess the efficacy safety acupuncture preventing or delaying incident among individuals with prediabetes.The following 8 databases will be searched from inception September 1, 2018: Cochrane Central Register Controlled Trials (CENTRAL) on Library, PubMed, Embase, Chinese National...

The aim of this study was to explore the associated risk factors perioperative respiratory adverse events (PRAEs) in children undergoing airway surgery and establish validate a nomogram prediction model for PRAEs.This involved 709 between November 2020 July 2021, aged ≤18 years affiliated hospital Xuzhou Medical University. They were divided into training (70%; n = 496) validation (30%; 213) cohorts. least absolute shrinkage selection operator (LASSO) used develop model. Concordance index...

The use of Unmanned Arial Systems (UAS) in both civil and military applications has greatly increased over the last few years. At same time, issues related to safety air traffic operation arise when considering UAS insertion into non-segregated airspace. Thus, surveillance plays a key role monitoring controlling traffic, enabling UASs manned aircrafts insure themselves against collision. Automatic Dependent Surveillance-Broadcast (ADS-B) been proposed as potential solution. It empowers...

The reinforced concrete (RC) piers of offshore bridges inevitably experience seawater freeze–thaw cycles due to the periodic movement tides in cold climates. damage caused by will reduce durability and mechanical properties concrete, then affect seismic performance RC piers. method analysis on numerical simulation is gradually emerging because process conventional experiment relatively complicated, heterogeneity degradation after should be considered. In this study, meso-element equivalent...

Abstract Studying the mechanical properties and failure mechanisms of damaged rocks holds practical significance in guiding tunnel or roadway support assessing stability engineering rock masses. To uncover sandy mudstone with varying degrees damage, we conducted cyclic loading‐unloading tests to create specimens at different damage levels. Subsequently, uniaxial loading were performed investigate fundamental properties, wave velocity, acoustic emission (AE) parameter evolution...

To investigate the effect of continuous erector spinae plane block (ESPB) on postoperative sleep in patients undergoing thoracoscopic lung lobe resection surgery.

Based on the engineering background of weakly cemented roadways and adjacent chambers in Western China, a numerical simulation method was used to examine changes stress distribution increment surrounding rock chambers. The results show that roadway increases by approximately 30%. vertical mainly expands along direction, expansion range is 7–12 times chamber height. horizontal 3–6 width. support idea “allowable deformation” + “relief pressure” “maintaining shape”, technology established with...