A5003404025- Cardiac Arrest and Resuscitation
- Simulation-Based Education in Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Anesthesia and Neurotoxicity Research
- Glaucoma and retinal disorders
- Neural and Behavioral Psychology Studies
- Traumatic Brain Injury Research
- Intensive Care Unit Cognitive Disorders
- Disaster Response and Management
- Autoimmune Neurological Disorders and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Traumatic Brain Injury and Neurovascular Disturbances
- Ocular Surface and Contact Lens
- Respiratory Support and Mechanisms
- Glycogen Storage Diseases and Myoclonus
- Cognitive Functions and Memory
- Public Administration and Political Analysis
- Law and Political Science
- EEG and Brain-Computer Interfaces
- Trauma and Emergency Care Studies
- Anesthesia and Sedative Agents
- Mechanical Circulatory Support Devices
- Malaria Research and Control
- Political Influence and Corporate Strategies
University Medical Center Hamburg-Eppendorf
2014-2024
Universität Hamburg
2014-2024
TU Dresden
2010-2016
Columbus Oncology and Hematology Associates
2016
University of Florida
2016
Charité - Universitätsmedizin Berlin
2000-2011
Johannes Gutenberg University Mainz
2001-2010
Washington University in St. Louis
2009-2010
University Medical Center of the Johannes Gutenberg University Mainz
2010
Justus-Liebig-Universität Gießen
2006-2007
Cognitive control and working memory processes have been found to be influenced by changes in motivational state. Nevertheless, the impact of different variables on behavior brain activity remains unclear.The current study examined incentive category varying a within-subjects basis whether performance during task was reinforced with either secondary (monetary) or primary (liquid) rewards. The temporal dynamics motivation-cognition interactions were investigated employing an experimental...
Identifying the processes by which people remember to execute an intention at appropriate moment ( prospective memory) remains a fundamental theoretical challenge. According one account, top-down attentional control is required maintain activation of intention, initiate retrieval, or support monitoring. A diverging account suggests that bottom-up, spontaneous retrieval can be triggered cues have been associated with and sustained are not required. We used specialized experimental design...
Affective variables have been shown to impact working memory and cognitive control. Theoretical arguments suggest that the functional of emotion on cognition might be mediated through shifting action dispositions related changes in motivational orientation. The current study examined effects positive negative affect performance via direct manipulation state tasks with high demands Experiment 1 monetary reward task-switching performance, while 2 both rewards punishments memory, using primary...
Journal Article Anaemia in pregnant Ghanaian women: importance of malaria, iron deficiency, and haemoglobinopathies Get access Frank P. Mockenhaupt, Mockenhaupt ∗ 1Institut für Tropenmedizin, Medizinische Fakultät Charité, Humboldt Universität zu Berlin, Germany ∗Address for correspondence: Dr med. F. Institut Spandauer Damm 130, 14050 Germany; phone +49 30 30116 750, fax 888. frank.mockenhaupt@charite.de Search other works by this author on: Oxford Academic PubMed Google Scholar Birgit...
Summary Malarial parasitaemia below the threshold of microscopy but detectable by polymerase chain reaction (PCR) assays is common in endemic regions. This study was conducted to examine prevalence, predictors, and effects submicroscopic Plasmodium falciparum infections pregnancy. In a cross‐sectional among 530 pregnant women Ghana, plasmodial were assessed PCR assays. Concentrations haemoglobin C‐reactive protein (CRP) measured antimalarial drugs (chloroquine, pyrimethamine) urine...
Continuous infusion of meropenem is a candidate strategy for optimization its pharmacokinetic/pharmacodynamic profile. However, plasma concentrations are difficult to predict in critically ill patients. Steady-state were determined prospectively during continuous 32 surgical ICU patients (aged 21-85 years, body weight 55-125 kg, APACHE II 5-29, measured creatinine clearance 22.7-297 mL/min). Urine was collected the quantification renal and creatinine. Cystatin C as an additional marker...
Cognitive control as well stress reactivity is assumed to depend on prefrontal dopamine and decline with age. Because Ginkgo biloba extract EGb761 increases in animals, we assessed its effects cognitive functions related dopamine.Effects of 240-mg daily task-set-switching, response-inhibition, delayed response, prospective-memory, task-related fMRI-BOLD-signals the Trier Social Stress-Test were explored a randomized, placebo-controlled, double-blind pilot-trial 61 elderly volunteers...
Abstract Background The Kids save lives statement recommends annual Basic Life Support (BLS) training for school children but the implementation is challenging. Trainings should be easy to realise and every BLS as effective possible prepare learners lifesaving actions. Preparedness implies skills positive beliefs in own capability (high self-efficacy). Methods This randomized controlled cluster study investigates, if self-regulated learning promotes self-efficacy long-term retention of...
Opsoclonus-myoclonus syndrome (OMS) is a rare neurologic disorder comprising the main symptoms of eye-movement disturbances, muscle jerks, and severe ataxia. In children adults, some cases are associated with tumor as paraneoplastic syndrome, whereas in form almost exclusively neuroblastoma. The detection autoantibodies OMS sera led to hypothesis that autoimmune origin. Beside against intracellular proteins, such anti-Hu, alpha-enolase, KHSRP, specific binding surface neuroblastoma cells...
Training of lay-rescuers is essential to improve survival-rates after cardiac arrest. Multiple campaigns emphasise the importance basic life support (BLS) training for school children. Trainings require a valid assessment give feedback children and compare outcomes different formats. Considering these requirements, we developed an BLS skills using MiniAnne tested inter-rater reliability between professionals, medical students trained as assessors. Fifteen professional assessors, 10...
Sedative premedication with benzodiazepines has been linked prolonged recovery and inadequate emergence during the immediate postoperative period. We aimed to analyze association between postanesthesia care unit (PACU) delirium sedative oral midazolam.We performed a secondary analysis of prospectively collected data before (midazolam cohort) after (non-midazolam implementation restrictive strategy for midazolam. From March 2015 until July 2018, we included patients 60 years older, who...
In ICU patients, glomerular filtration is often impaired, but also supraphysiological values are observed (“augmented renal clearance”, >130 mL/min/1.73 m2). Renally eliminated drugs (e.g. many antibiotics) must be adjusted accordingly, which requires a quantitative measure of function throughout all the range clinically encountered values. Estimation from plasma creatinine standard, cystatin C may valuable alternative. This was secondary analysis parameters in 100 patients two...
Abstract Background Delayed neurocognitive recovery (DNCR) is a common and serious complication after radical prostatectomy. We hypothesized that patients with DNCR in the early postoperative period would report reduced health-related quality of life (HRQoL) more cognitive failures 12 months surgery, compared without DNCR. Methods performed 12-month follow-up on 367 who had been enrolled prospective observational trial to study incidence Patients were screened for preoperative impairment...