Donna Mergler

ORCID: 0000-0002-5205-5180
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Heavy Metal Exposure and Toxicity
  • Mercury impact and mitigation studies
  • Heavy metals in environment
  • Air Quality and Health Impacts
  • Pesticide Exposure and Toxicity
  • Chemical Safety and Risk Management
  • Trace Elements in Health
  • Carcinogens and Genotoxicity Assessment
  • Health, Environment, Cognitive Aging
  • Occupational Health and Safety Research
  • Child Nutrition and Water Access
  • Toxic Organic Pollutants Impact
  • Indigenous Health and Education
  • Selenium in Biological Systems
  • Effects and risks of endocrine disrupting chemicals
  • Climate Change and Health Impacts
  • Visual perception and processing mechanisms
  • Dye analysis and toxicity
  • Environmental Toxicology and Ecotoxicology
  • Workplace Health and Well-being
  • Posttraumatic Stress Disorder Research
  • Occupational exposure and asthma
  • Fatty Acid Research and Health
  • Olfactory and Sensory Function Studies
  • Fish biology, ecology, and behavior

Université du Québec à Montréal
2016-2025

Midlands State University
2022

Centre for Interdisciplinary Research in Rehabilitation
2020

Université du Québec
1988-2010

University of Northern British Columbia
2006

McGill University
2005-2006

Institute for Environmental Sciences
2006

San Francisco State University
1989-2006

Institut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail
2006

Université de Montréal
2001-2006

Manganese is an essential nutrient, but in excess it can be a potent neurotoxicant. Despite the common occurrence of manganese groundwater, risks associated with this source exposure are largely unknown.Our first aim was to assess relations between from drinking water and children's intelligence quotient (IQ). Second, we examined exposures consumption diet hair concentration.This cross-sectional study included 362 children 6-13 years age living communities supplied by groundwater....

10.1289/ehp.1002321 article EN public-domain Environmental Health Perspectives 2010-09-20

BackgroundNeurotoxic effects are known to occur with inhalation of manganese particulates, but very few data available on exposure Mn in water. We undertook a pilot study community Québec (Canada) where naturally occurring high levels were present the public water system. Our objective was test hypothesis that greater via drinking would be reflected higher content hair which, turn, associated increased level hyperactive behaviors.MethodsForty-six children participated study, 24 boys and 22...

10.1289/ehp.9504 article EN public-domain Environmental Health Perspectives 2006-10-03

Background: Manganese neurotoxicity is well documented in individuals occupationally exposed to airborne particulates, but few data are available on risks from drinking-water exposure.Objective: We examined associations of exposure concentrations manganese water and hair with memory, attention, motor function, parent- teacher-reported hyperactive behaviors.Methods: recruited 375 children measured home tap (MnW) (MnH). estimated intake ingestion. Using structural equation modeling, we between...

10.1289/ehp.1307918 article EN public-domain Environmental Health Perspectives 2014-09-26

<b>Background:</b> Although adverse neuropsychological and neurological health effects are well known among workers with high manganese (Mn) exposures in mining, ore-processing ferroalloy production, the risks welders lower less understood. <b>Methods:</b> Confined space welding construction of a new span San Francisco–Oakland Bay Bridge without adequate protection was studied using multidisciplinary method to identify dose–effect relationship between Mn air or whole blood. (n = 43) little...

10.1136/oem.2006.028761 article EN Occupational and Environmental Medicine 2006-10-03

Polychlorinated biphenyls (PCBs), chlorinated pesticides, and mercury are global environmental contaminants that can disrupt the endocrine system in animals humans. However, there is little evidence they interfere with status pregnant women neonates at low levels of exposure. The aim this study was to examine thyroid hormone during pregnancy cord blood relation concentrations organochlorine compounds (OCs) Hg healthy recruited pregnancy. We found a significant negative correlation between...

10.1289/ehp.7685 article EN public-domain Environmental Health Perspectives 2005-05-20

Abstract Background Fish is considered protective for coronary heart disease (CHD), but mercury (Hg) intake from fish may counterbalance beneficial effects. Although neurotoxic effects of methylmercury (MeHg) are well established, cardiovascular still debated. The objective the present study was to evaluate blood pressure in relation Hg exposure and consumption among a non-indigenous fish-eating population Brazilian Amazon. Methods conducted 251 persons six communities along Tapajós River,...

10.1186/1476-069x-5-29 article EN cc-by Environmental Health 2006-10-10

Certain pesticides may affect children's neurodevelopment. We assessed whether pesticide exposure was associated with impaired neurobehavioral outcomes in children aged 6–9 years. conducted a cross-sectional study 140 living near banana plantations and plantain farms the Talamanca County, Costa Rica their performance. Exposure determined by analyzing urinary metabolites of chlorpyrifos (3,5,6-trichloro-2-pyridinol, TCPy), mancozeb (ethylenethiourea, ETU), pyrethroids (3-phenoxybenzoic acid,...

10.1016/j.cortex.2016.09.003 article EN cc-by-nc-nd Cortex 2016-09-16

Manganese is an essential element, but excessive manganese exposure has neurotoxic effects.To examine blood levels in the general population with respect to sex, age, race/ethnicity, pregnancy and menauposal status, as well of trace elements blood.We used data from National Health Nutrition Examination Survey, a national survey U.S. residents (n = 7720 participants, ages 1 80 years). General linear models generalized additive were association between concentration participants'...

10.1186/1476-069x-13-87 article EN cc-by Environmental Health 2014-10-24

In recent decades there has been an increasing recognition of the need to account for sex and gender in biology medicine, order develop a more comprehensive understanding biological phenomena address gaps medical knowledge that have arisen due generally masculine bias research.We noted as basic experimental biomedical researchers, we face unique challenges incorporation our work, these remained largely unarticulated, misunderstood, unaddressed literature.Here, describe some specific...

10.1096/fj.13-233395 article EN The FASEB Journal 2013-09-20

Mercury (Hg) is a ubiquitous environmental contaminant with neurodevelopmental and immune system effects. An informative biomarker of Hg-induced immunotoxicity could aid studies on the potential contribution to immune-related health effects.Our objectives were test hypothesis that methylmercury (MeHg) exposures affect levels serum biomarkers examine interactions between Hg selenium (Se) in terms these responses.This cross-sectional epidemiological study assessed adults living along Tapajós...

10.1289/ehp.1103741 article EN public-domain Environmental Health Perspectives 2011-08-25
Coming Soon ...