Hongyi Chen

ORCID: 0000-0002-5207-6651
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Trauma Management and Diagnosis
  • Geology and Paleoclimatology Research
  • Digital Economy and Work Transformation
  • Tracheal and airway disorders
  • Hepatitis C virus research
  • Aeolian processes and effects
  • Salivary Gland Tumors Diagnosis and Treatment
  • Peer-to-Peer Network Technologies
  • Marine and environmental studies
  • Tree Root and Stability Studies
  • Ethics in Business and Education
  • SARS-CoV-2 detection and testing
  • Medical Research and Treatments
  • Gastrointestinal Tumor Research and Treatment
  • Transplantation: Methods and Outcomes
  • Ear and Head Tumors
  • Infectious Encephalopathies and Encephalitis
  • Tree-ring climate responses
  • Hormonal and reproductive studies
  • Caching and Content Delivery
  • Landslides and related hazards
  • Neurological Disorders and Treatments
  • Bacteriophages and microbial interactions

Yuxian People's Hospital
2024

Zhejiang University
2024

ShanghaiTech University
2023

Xiamen University
2023

Hangzhou Normal University
2021

Dalian Medical University
2021

Second Affiliated Hospital of Dalian Medical University
2021

Nanjing Institute of Technology
2021

Wuhan No.9 Hospital
2020

Ninth Hospital of Nanchang
2020

As coronavirus disease 2019 (COVID-19) outbreak globally, repurposing approved drugs is emerging as important therapeutic options. Danoprevir boosted by ritonavir (Ganovo) a potent hepatitis C virus (HCV) protease (NS3/4A) inhibitor, which was and marketed in China since 2018 to treat chronic patients.This an open-label, single arm study evaluating the effects of danoprevir on treatment naïve experienced COVID-19 patients for first time. Patients received (100 mg/100 mg, twice per day). The...

10.1097/md.0000000000023357 article EN cc-by-nc Medicine 2020-11-23

Abstract As coronavirus disease 2019 (COVID-19) outbreak, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), started in China January, 2020, repurposing approved drugs is emerging as important therapeutic options. We reported here first clinical study using hepatitis C virus (HCV) protease inhibitor, danoprevir, to treat COVID-19 patients. Danoprevir (Ganovo®) a potent HCV (NS3/4A) inhibitor (IC50 = 0.29 nM), which was and marketed since 2018 chronic Ritonavir CYP3A4...

10.1101/2020.03.22.20034041 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2020-03-24

In late December 2019, coronavirus disease 2019 (COVID-19) first broke out in Wuhan, China, and has now become a global pandemic. However, there is no specific antiviral treatment for COVID-19. This study enrolled 33 COVID-19 patients the nineth hospital of Nanchang from 27th January to 24th February 2020. Clinical indexes upon admission/discharge were examined. Patients divided into two groups according different plans (danoprevir lopinavir/ritonavir). The days achieve negative nucleic acid...

10.1002/jmv.26141 article EN Journal of Medical Virology 2020-06-05

Morality-based interventions designed to promote academic integrity are being used by educational institutions around the world. Although many such approaches have a strong theoretical foundation and supported laboratory-based evidence, they often not been subjected rigorous empirical evaluation in real-world contexts. In naturalistic field study (N = 296), we evaluated recent research-inspired classroom innovation which students told, just prior taking an unproctored exam, that trusted act...

10.1177/0956797620977513 article EN Psychological Science 2021-04-15

Context In recent years, Phaeocystis globosa has become a typical red tide species in the Beibu Gulf, posing safety hazard to cold-water intake system of Guangxi Fangchenggang Nuclear Power Plant. Aims To establish an effective early risk-warning monitoring and ensure nuclear power plant intakes. Methods this study, multifactor multilevel was established using warning idea ‘risk grading’. Key results The showed that method can analyse influence trend marine-environment changes on growth P....

10.1071/mf23179 article EN Marine and Freshwater Research 2024-01-29

Abstract Background We retrospectively reviewed and consecutively collected the clinical data of distal gastric cancer patients who received surgical treatment, we discuss safety feasibility double layered end-to-end anastomosis with continuous manual suture to complete digestive tract reconstruction in totally laparoscopic gastrectomy. Methods 41 from gastroenterology department Second Affiliated Hospital Dalian Medical University, September 2018 August 2019, underwent During operation,...

10.1186/s12893-021-01207-1 article EN cc-by BMC Surgery 2021-04-26

Abstract Background There are numerous viruses in the rumen that interact with other microorganisms, which play crucial roles regulating environmental metabolism. However, knowledge of is limited, and their relationship production traits (e.g., feed efficiency) has not been reported. In this study, we combined next-generation sequencing (NGS) HiFi to investigate DNA virome reveal potential mechanisms how influence efficiency dairy cows. Results Compared NGS, improved length, completeness,...

10.21203/rs.3.rs-4199008/v1 preprint EN cc-by Research Square (Research Square) 2024-04-18

This study examined the association between incidence of diabetic retinopathy (DR) in male with type 2 diabetes mellitus (T2DM) and levels systemic immunoinflammatory index (SII), platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte (NLR).A total 719 T2DM men participated this study.Patients' basic information, physical examinations, laboratory examinations were collected.DR was screened for independent influencing variables using both univariate multivariate logistic regression analysis.A...

10.22514/jomh.2024.076 article EN Journal of Men s Health 2024-01-01

Abstract BackgroundIn late December 2019, the coronavirus disease 2019 (COVID-19) first outbroke in Wuhan city, China, and has now become a global pandemic. However, there is no specific antiviral treatment for COVID-19.MethodsThis study was approved by Ethics Committee of Ninth Hospital Nanchang. This enrolled 33 COVID-19 patients nineth hospital Nanchang from January 27th to February 24th, 2020. Clinical indexes upon admission/discharge were examined. Patients divided into two groups...

10.21203/rs.3.rs-28376/v1 preprint EN cc-by Research Square (Research Square) 2020-05-29

Fushi (服食), a method for treating diseases and nourishing life to achieve longevity, is highly valued widely used in traditional Taoism. Regarding whether Quanzhen Taoism, new form of Taoism founded the Jin Dynasty (1115–1234), practices Fushi, contradictory opinions have been recorded Collected records written on Qingyan Mountain (Qingyan conglu 青巖叢錄) from end Yuan (1271–1368) The History Taoist School by (Qiu) Changchun (Changchun daojiao yuanliu 長春道教源流) late Qing (1636–1912). Today’s...

10.3390/rel14060814 article EN cc-by Religions 2023-06-20

Even to this day, limited studies have suggested a relationship between testosterone and SUA. The results of them are also controversial. In order better understand potential relationship, we looked into adult males in the United States. Data from National Health Nutrition Examination Survey 2013–2016 were gathered, containing 1919 male participants aged 18-64 years with required data existing. A summary all useful participants' characteristics among different SUA groups is conducted. We...

10.1117/12.2669014 article EN 2023-03-24
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