A5040828828- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Genomics and Phylogenetic Studies
- Cancer-related molecular mechanisms research
- Genetic diversity and population structure
- Animal Genetics and Reproduction
- Identification and Quantification in Food
- Human-Animal Interaction Studies
- Livestock and Poultry Management
- Reproductive Physiology in Livestock
- Animal Diversity and Health Studies
- Livestock Farming and Management
- RNA modifications and cancer
- Animal Nutrition and Physiology
- Molecular Biology Techniques and Applications
- CRISPR and Genetic Engineering
- Rabies epidemiology and control
- Chromosomal and Genetic Variations
- Effects of Environmental Stressors on Livestock
- Animal Disease Management and Epidemiology
- Milk Quality and Mastitis in Dairy Cows
- Veterinary Equine Medical Research
- Genetics and Physical Performance
- Plant and Fungal Interactions Research
- Plant responses to water stress
Agricultural Research & Education Organization
2024-2025
Northwest A&F University
2020-2025
Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences
2025
Shahid Bahonar University of Kerman
2016-2024
Biotechnology Research Center
2023
Academic Center for Education, Culture and Research
2023
Agriculture and Forestry University
2020
National Museums of Kenya
2019
Isfahan University of Technology
2013-2016
Structural variations (SVs) are a major contributor to genetic diversity and phenotypic variations, but their prevalence functions in domestic animals largely unexplored. Here we generated high-quality genome assemblies for 15 individuals from genetically diverse sheep breeds using Pacific Biosciences (PacBio) high-fidelity sequencing, discovering 130.3 Mb nonreference sequences, which 588 genes were annotated. A total of 149,158 biallelic insertions/deletions, 6531 divergent alleles, 14,707...
Pistachio (Pistacia vera), one of the most important commercial nut crops worldwide, is highly adaptable to abiotic stresses and tolerant drought salt stresses.Here, we provide a draft de novo genome pistachio as well large-scale resequencing. Comparative genomic analyses reveal stress adaptation likely attributable expanded cytochrome P450 chitinase gene families. Particularly, comparative transcriptomic analysis shows that jasmonic acid (JA) biosynthetic pathway plays an role in tolerance...
Abstract Background Sheep were among the first animals to be domesticated. They are raised all over world and produce a major scale of animal-based protein for human consumption play an important role in agricultural economy. Iran is one locations sheep genetic resources world. Here, we compared Illumina Ovine SNP50 BeadChip data three Iranian local breeds (Moghani, Afshari Gezel), as population that does not undergone artificial breeding programs yet, five other namely East Friesian white,...
Chinese indicine cattle harbor a much higher genetic diversity compared with other domestic cattle, but their genome architecture remains uninvestigated. Using PacBio HiFi sequencing data from 10 across southern China, we assembled 20 high-quality partially phased genomes and integrated them into multiassembly graph containing 148.5 Mb (5.6%) of novel sequence. We identified 156,009 high-confidence nonredundant structural variants (SVs) 206 SV hotspots spanning ∼195 gene-rich detected 34,249...
The geographic origin and migration of the brown rat (Rattus norvegicus) remain subjects considerable debate. In this study, we sequenced whole genomes 110 wild rats with a diverse world-wide representation. We reveal that migrated out southern East Asia, rather than northern Asia as formerly suggested, into Middle then to Europe Africa, thousands years ago. Comparison from different geographical populations reveals many genes involved in immune system experienced positive selection rat.
Abstract Ruminant Genome Database (RGD; http://animal.nwsuaf.edu.cn/RGD) provides visualization and analysis tools for ruminant comparative genomics functional annotations. As more high-quality genome assemblies have become available, we redesigned the user interface, integrated expanded multi-omics data, developed novel features to improve database. The new version, RGD v2.0, houses 78 genomes; 110-species synteny alignments major livestock (including cattle, sheep, goat) wild ungulates; 21...
Abstract During the process of animal domestication, both natural and artificial selection cause variation in allele frequencies among populations. Identifying genomic areas domestic animals may aid detection linked to ecological economic traits. We studied 140 worldwide goat individuals, including 75 Asian, 30 African 35 European goats. further carried out comparative population genomics detect regions under for adaptability harsh conditions local Asian ecotypes also milk production traits...
Abstract Background Goat, one of the first domesticated livestock, is a worldwide important species both culturally and economically. The current goat reference genome, known as ARS1, reported nonhuman genome assembly using 69× PacBio sequencing. However, ARS1 suffers from incomplete X chromosome highly fragmented Y scaffolds. Results Here, we present very high-quality de novo assembly, Saanen_v1, male Saanen dairy goat, with scaffold based on 117× long-read sequencing 118× Hi-C data....
The Chantecler chicken, a unique Canadian indigenous breed, is well adapted to extremely cold environments. However, its genetic characteristics have not been studied. Here, we analyzed the whole genomes of 10 chickens and 121 worldwide chickens, which indicated that were derived from commercial exhibit high level inbreeding. Based on genome-wide scan, identified two vital candidate regions containing ME3 ZNF536, are related fat metabolism nervous system in adaptation, respectively. We also...
Abstract Background Understanding how evolutionary forces relating to climate have shaped the patterns of genetic variation within and between species is a fundamental pursuit in biology. Iranian indigenous chickens evolved adaptations their local environmental conditions, such as hot arid regions. In present study, we provide population genome landscape variations 72 representing nine ecotypes (Creeper, Isfahan, Lari, Marand, Mashhad, Naked neck, Sari, Shiraz Yazd) two commercial lines...
Abstract Background Artificial and natural selection for important economic traits genetic adaptation of the populations to specific environments have led changes on sheep genome. Recent advances in genome sequencing methods made it possible use comparative genomics tools identify genes under interest domestic animals. Objectives In this study, we compared genomes Assaf Awassi breeds with those Cambridge, Romanov British du cher explore positive signatures milk using nucleotide diversity...
Abstract Background Since domestication, both evolutionary forces and human selection have played crucial roles in producing adaptive economic traits, resulting animal breeds that been selected for specific climates different breeding goals. Pakistani goat acquired genomic adaptations to their native climate conditions, such as tropical hot climates. In this study, using next-generation sequencing data, we aimed assess the signatures of positive three goats, known milk production breeds,...
Contents Ovulation rate and prolificacy are the most important reproductive traits that have major impact on efficiency of lamb meat production. Here, we compared whole genomes Romanov sheep, known as one high prolific breeds, four other sheep breeds namely Assaf, Awassi, Cambridge British du cher, to identify genetic mechanisms underlying in sheep. Selection signature analysis revealed 637 477 protein‐coding genes under positive selection from F ST nucleotide diversity (Pi) statistics,...
Abstract The origin of domestic sheep ( Ovis aries ) can be traced back to the Asian mouflon gmelini ), in Near East around 10 000 years ago. Genetic divergence within populations occur due factors such as geographical isolation, social structures, and environmental pressures, leading different affinities with sheep. However, few studies have reported extent which contribute regions. Here, we implemented demographic analyses across globe based on whole genome resequencing data 410 samples, Y...
Coat color polymorphism in domestic animals provides a robust framework for elucidating mechanisms of species adaptation, domestication, and genomic diversity. Leiqiong cattle, representative indicine breed from southern China, are predominantly yellow-coated, although subset exhibits solid black phenotype. To determine the genetic basis this variation, genome-wide association study (GWAS) was performed 212 bulls. A pronounced signal detected on chromosome 6 within fifth intron CORIN gene,...
Goats are essential to the dairy industry in Shaanxi, China, with udder traits playing a critical role determining milk production and economic value for breeding programs. However, direct measurement of these goats is challenging resource-intensive. This study leveraged genotyping imputation explore genetic parameters architecture assess efficiency genomic prediction methods. Using data from 635 Saanen goats, genotyped over 14,717,075 SNP markers phenotyped three traits, heritability was...
Abstract Background Body size is considered as one of the most fundamental properties an organism. Due to intensive breeding and artificial selection throughout domestication history, horses exhibit striking variations for heights at withers body sizes. Debao pony (DBP), a famous Chinese horse, known its small lives in Guangxi mountains southern China. In this study, we employed comparative population genomics study genetic basis underlying DBP breed based on whole genome sequencing data. To...
Understanding how evolutionary pressures related to climate change have shaped the current genetic background of domestic animals is a fundamental pursuit biology. Here, we generated whole-genome sequencing data from native goat populations in Iraq and Pakistan. Combined with previously published on modern, ancient (Late Neolithic Medieval periods), wild Capra species worldwide, explored population structure, ancestry components, signatures natural positive selection Southwest Asia (SWA)....