Zhicheng Li

ORCID: 0000-0002-5271-3753
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About
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Research Areas
  • Hearing, Cochlea, Tinnitus, Genetics
  • Vestibular and auditory disorders
  • Hearing Loss and Rehabilitation
  • Ear Surgery and Otitis Media
  • Neuroscience and Neuropharmacology Research
  • Noise Effects and Management
  • Neuroscience of respiration and sleep
  • Free Radicals and Antioxidants
  • Multisensory perception and integration
  • Human Health and Disease
  • Neural Networks and Applications
  • Photochromic and Fluorescence Chemistry
  • Cytomegalovirus and herpesvirus research
  • Cerebrospinal fluid and hydrocephalus
  • Retinal Development and Disorders
  • Delphi Technique in Research
  • Olfactory and Sensory Function Studies
  • Consumer Perception and Purchasing Behavior
  • Cardiovascular Health and Risk Factors
  • Healthcare and Venom Research
  • Vagus Nerve Stimulation Research
  • Crystallography and molecular interactions
  • Microencapsulation and Drying Processes
  • Neurological Disorders and Treatments
  • Nicotinic Acetylcholine Receptors Study

Third Affiliated Hospital of Sun Yat-sen University
2013-2025

Sun Yat-sen University
2013-2025

Chinese PLA General Hospital
2022

National Clinical Research Center for Digestive Diseases
2021

South China Normal University
2008-2019

Pudong Medical Center
2013

University of Tennessee Health Science Center
1997-1998

GTx (United States)
1997

Abstract Methyl methacrylate (MMA)–styrene (St) copolymer nanocapsules containing cologne essential oil for fragrant fabrics treatment were prepared by miniemulsion polymerization. The morphology, chemical composition and thermal properties characterized scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT‐IR) gravimetric analysis (TGA). had relatively small size (ca. 136 nm of mean particle diameter), regular sphericity uniform distribution. encapsulation...

10.1002/ffj.3245 article EN Flavour and Fragrance Journal 2015-04-02

Objective:To retrospectively analyze the results of auditory examination,vestibular function examination and laboratory 63 patients diagnosed as vestibular neuritis.Methods:A total with neuritis hospitalized in Department Otolaryngology, Head Neck Surgery Third Affiliated Hospital Sun Yat-sen University, from October 2012 to December 2022 were recruited. All met diagnostic criteria for Bárány association neuritis. Clinical data pure tone audiometry, electrocochleogram, video...

10.13201/j.issn.2096-7993.2025.01.005 article EN PubMed 2025-01-01

In the past decade, with advancement and implementation of sequencing technology, millions human genomes have been sequenced, a plethora sequences could be accessed in public databases. Consequently, various genetic changes within ABO genes identified.1 Here, we report novel B allele variation (c.567G>A) exon 7 ABO*B.01 allele, which is associated weak phenotype. The proband was 6-year-old girl from clinical hospital. phenotype determined using traditional tube methods, involved use anti-A,...

10.1111/trf.18175 article EN other-oa Transfusion 2025-02-22

An abnormal state of the central auditory system (CAS) likely plays a large role in occurrence phantom sound tinnitus. Various tinnitus studies using resting-state functional MRI (RS-fMRI) have reported aberrant spontaneous brain activity non-auditory and altered connectivity between CAS system. This study aimed to investigate connections whole patients, compared healthy controls (HC) RS-fMRI.RS-fMRI from 16 right-ear patients with normal hearing (TNHs) 15 HC individuals was collected, time...

10.3389/fnins.2019.01314 article EN cc-by Frontiers in Neuroscience 2019-12-20

Epilepsy is a disease caused by abnormal discharges in the central nervous system. Automatic detection and accurate identification of epileptic seizures based on electroencephalography (EEG) are significant clinical diagnosis treatment epilepsy. In this paper, we first decompose patient's EEG signal into multiple intrinsic modal functions (IMFs) using empirical decomposition, then compute mean, standard deviation, fluctuation index, sample entropy IMF1, finally classify them fusion algorithm...

10.1002/int.23040 article EN International Journal of Intelligent Systems 2022-08-26

Tinnitus refers to the auditory perception of sound in absence external or electric stimuli. The influence tinnitus on cognitive processing is at cutting edge ongoing research. In this study, we adopted an objective indicator attentional processing, i.e. mismatch negativity (MMN), assess bias patients with decompensated tinnitus. Three kinds pure tones, D1 (8,000 Hz), S (8,500 Hz) and D2 (9,000 were used induce event-related potentials (ERPs) normal ear. Employing oddball paradigm, task was...

10.1159/000441709 article EN Audiology and Neurotology 2016-01-01

Background: Cancer stem cells (CSCs) have been demonstrated to play a vital role in diversity of biological processes cancers. With the emergence new evidence, important function CSCs formation multidrug resistance nasopharyngeal cancer has demonstrated. Dysregulated Wnt/β-catenin signaling pathway is an contributor chemoresistance and maintenance CSCs-like characteristics. This research aims investigate comprehensively dihydromyricetin (DMY), natural flavonoid drug, on cisplatin (cis) cell...

10.1177/1534735421991217 article EN cc-by-nc Integrative Cancer Therapies 2021-01-01

Due to the socio-cultural differences between China and other countries, which may affect development of an individual's personality behavior, it is necessary explore relationship traits tinnitus distress in context China's background.The Tinnitus Handicap Inventory Eysenck Personality Questionnaire Short Scale Chinese version were used influence on patients with tinnitus.The results not entirely consistent previous studies from countries. First, extroversion was significantly higher...

10.4103/nah.nah_68_22 article EN cc-by-nc-sa Noise and Health 2023-01-01

10.1016/j.jfma.2013.09.003 article EN Journal of the Formosan Medical Association 2013-09-29

At present, the mechanisms underlying changes in visual processing individuals with tinnitus remain unclear. We therefore investigated whether vision dominates of disappear at preresponse level through behavioral study. A total 38 and 31 healthy controls completed a task which they were asked to attend either or auditory stimuli while ignoring simultaneous stimulus inputs from other modality. manipulated three levels congruency between inputs: congruent (C), incongruent (PRIC), response...

10.3389/fnins.2019.00482 article EN cc-by Frontiers in Neuroscience 2019-05-14

The visual processing capacity of tinnitus patients is worse than normal controls, indicating cross-modal interference. However, the mechanism underlying tinnitus-modulated largely unclear. In order to explore influence on processing, this study used a signal recognition paradigm observe whether group would display significantly longer reaction time in letter symbols (Experiment 1) and emotional faces 2) control group. Signal detection recognition, which reflect perceptual conceptual aspects...

10.3389/fpsyg.2018.01779 article EN cc-by Frontiers in Psychology 2018-09-24

Abstract Degeneration of cholinergic neurons in the basal forebrain is a neural marker ofAlzheimers disease and associated with perceptual cognitive deficits. An idea that hasattracted scientific scutiny aging makes brain more susceptible to neurodegenerativediseases such as Alzheimers. The purpose this study was compare effects loss ofcholinergic input from nucleus basalis Meynert on evoked activity posteromedial barrelsubfield somatosensory cortex young (2–2.5 months) aged (28–30...

10.1016/s0736-5748(98)00074-4 article EN International Journal of Developmental Neuroscience 1998-11-01

Abstract Background: To improve healthcare quality, a preventive intervention system has been developed globally with routine newborn screening, diagnosis, intervention, and rehabilitation for congenital hearing impairment. An program Newborn Hearing Screening (NHS) was implemented in Guangdong Province, China, 1999, along molecular screening common inherited deafness mutations since 2011. Methods: We evaluated the clinical data impairment results of genetic testing genes that were collected...

10.29011/2577-2228.100400 article EN Journal of Community Medicine & Public Health 2024-01-15

The aim of this study was to explore the impact sleep quality on cognitive function in patients with chronic subjective tinnitus.

10.5152/iao.2024.231179 article EN The Journal of International Advanced Otology 2024-02-01

This study aimed to explore the correlation between extent of fundus damage and severity strategies for chronic kidney disease (CKD).

10.1159/000542363 article EN cc-by-nc Kidney & Blood Pressure Research 2024-11-11

<b><i>Introduction:</i></b> The role of social support in the relief tinnitus distress and related mechanisms remains unclear. This study aimed to confirm a hypothesis that influence on is mediated by resilience self-esteem. <b><i>Methods:</i></b> Social Support Rating Scale, Connor-Davidson Resilience Positive Version Rosenberg Self-Esteem Tinnitus Handicap Inventory were used assess 296 patients who experience chronic subjective tinnitus....

10.1159/000511254 article EN Audiology and Neurotology 2021-01-01

Our objective was to study the efficacy and safety of intratymapanic dexamethasone (ITD) for treating in Méniere's disease southern China.A total 124 patients with were randomly divided into 2 groups: ITD group (n = 62) intratympanic lidocaine (ITL) 62). The further groups based on dosage: ITD1 (2 mg/ml) 31) ITD2 (5 31). Symptom alleviation complications recorded after every treatment.Vertigo improved 65% who received compared 55% ITL (P < .05). Three had from otomycosis, these a...

10.1177/01455613221120729 article EN cc-by-nc Ear Nose & Throat Journal 2022-09-24

The dinuclear title compound, [Cd2(C7H5O3)4(C12H8N2)2], is located on a crystallographic rotation twofold axis. two CdII ions are connected by tridentate bridging 2-hydroxy­benzoate anions. Each ion seven-coordinated five O atoms from three ligands and N 1,10-phenanthroline. mol­ecules adopt kinds of coordination mode, bidentate chelating bridging–chelating. Intra­molecular hydrogen bonds between hydr­oxy carboxyl­ate groups π–π stacking interactions parallel 1,10-phenanthroline...

10.1107/s1600536808033886 article EN cc-by Acta Crystallographica Section E Structure Reports Online 2008-10-24

The narrowband chirp (NB Chirp), a frequency-specific sound stimulus signal obtained by limiting the frequency bandwidth based on chirp, is applied to specified auditory brainstem response (fsABR) increasingly. Although some studies demonstrated that NB Chirp-evoked Chirp ABR) causes better neural than tone burst-evoked and preferred for fsABR, there little known about how estimate an individual's hearing level through threshold of ABR. present study intended compare accuracy deviation ABR...

10.1159/000523918 article EN Audiology and Neurotology 2022-01-01

Objective:The aim of this study is to investigate the efficacy transcutaneous vagus nerve stimulation(taVNS) in treatment chronic tinnitus. Methods:taVNS was used treat decompensated tinnitus, 10 days as a course treatment. Record and analyze improvement patient's subjective symptoms during The THI, PSQI DASS-21 scores were performed at days, 3 months 6 after tinnitus taVNS group control above recorded time points compared, THI score compared before Results:① During treatment, 93.65%...

10.13201/j.issn.2096-7993.2021.02.003 article EN PubMed 2021-02-01
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