A5013437877- Microgrid Control and Optimization
- Multilevel Inverters and Converters
- Advanced DC-DC Converters
- Seismic Performance and Analysis
- Structural Health Monitoring Techniques
- Structural Response to Dynamic Loads
- HVDC Systems and Fault Protection
- Structural Engineering and Vibration Analysis
- Advanced Memory and Neural Computing
- Vibration Control and Rheological Fluids
- Ferroelectric and Negative Capacitance Devices
- High-Voltage Power Transmission Systems
- Masonry and Concrete Structural Analysis
- Wireless Power Transfer Systems
- Wind and Air Flow Studies
- Polydiacetylene-based materials and applications
- Smart Grid and Power Systems
- Islanding Detection in Power Systems
- Optimal Power Flow Distribution
- Olfactory and Sensory Function Studies
- Silicon Carbide Semiconductor Technologies
- Power Systems and Renewable Energy
- RNA Interference and Gene Delivery
- Advanced Battery Technologies Research
- Advanced Nanomaterials in Catalysis
Peking University Cancer Hospital
2025
Sichuan University
2020-2024
Harbin Institute of Technology
2015-2024
National University of Singapore
2022-2024
Peking University
2024
South China University of Technology
2022-2023
Institute of Process Engineering
2019-2023
China Earthquake Administration
2023
Chengdu University
2022
Shandong First Medical University
2019-2021
The treatment of Parkinson's disease (PD) has been hindered by the complex pathologies and multiple membrane barriers during drug delivery. Although exosomes derived from mesenchymal stem cells (MSCs) have great potential for PD, MSC-derived alone could not fully meet therapeutic requirements due to their limitation in therapy Here, we develop a self-oriented nanocarrier called PR-EXO/PP@Cur that combines with curcumin. can be across directly release drugs into cytoplasm target after...
A particle swarm optimization (PSO) algorithm-based staircase modulation strategy for modular multilevel converters (MMC) is proposed. To reduce switching losses and device stress, the method has been adopted in high-voltage high-power energy conversion applications. In particular, selection of appropriate iterative initial values angles a significant step to realize modulated MMC. The proposed able find optimum angles, while it advantages global quadratic convergence, which benefit from PSO...
Magnetic skyrmion technology is promising for the next-generation spintronics-based memory and neuromorphic computing due to their small size, non-volatility low depinning current density. However, Magnus force originating from Hall effect causes move along a curved trajectory, which may lead annihilation of in nanotrack during current-induced motion. Consequently, circuits utilizing skyrmionic motion need be designed limit impact effect. In this work, we propose design an artificial neuron,...
Gene therapy has shown great potential for neurodegenerative diseases with complex pathology. However, its therapeutic effect is limited due to the delivery barriers and own single function. Herein, self-catalytic small interfering RNA (siRNA) nanocarriers (S/Ce-PABMS) are developed catalyze process treatment synergistic of diseases. On one hand, rough surface S/Ce-PABMS mediated by ceria (CeO2 ) nanozymes can cellular uptake in process, so that acetylcholine analogs penetrate blood-brain...
Inspired by the fact that leukocytes have innate phagocytic functions and oriented migration capabilities in response to chemoattractants, we unveiled endogenous neutrophils as "Trojan horses", participate delivery of nanoparticles an "in vivo self-armed assembly" manner. Neutrophils were main population preferentially sequester intravenous administrated with average size 260 nm. The pre-implantation CXCL1-laden hydrogels could trigger induce a targeted signal attract influx carrying...
Osthole (OST) is a natural coumarin compound that exerts multiple pharmacologic effects. However, the poor water solubility and low oral absorption of OST limit its clinical application for treatment neurologic diseases. A suitable preparation needs to be tailored evade these unfavourable properties OST. In this study, an nanoemulsion (OST‐NE) was fabricated according pseudoternary phase diagram method, which generally used optimize prescription in light surfactants cosurfactants. The final...
Radiotherapy (RT) is a primary treatment for breast cancer, but its effectiveness often compromised by hypoxia and intrinsic resistance mechanisms. The F-box protein JFK overexpressed in cancer associated with reduced radiosensitivity, specific inhibitors are currently unavailable. Herein, we developed spherical nanoparticles (SNP-JC) designed to co-deliver small interfering RNA targeting catalase the tumor, aiming silence alleviate overcome RT resistance. Positron emission tomography...
A modulation reconfiguration based fault-tolerant method is proposed for the modular multilevel converter (MMC) system. practical to reconfigure reference sine wave from point of view that output line-to-line voltages should be guaranteed well regulated and not vary. Voltage balancing sub-module capacitors achieved while using carrier rotation algorithm multicarrier pulse width modulation. Experimental results obtained laboratory system verified validity reliability control in MMC application.
Summary The tuned liquid damper (TLD) and particle (PD) have been used as effective passive vibration absorbers to suppress undesirable structural vibrations induced by dynamic loads such earthquake strong winds. In this paper, through an integrated use of the TLD PD, a new system named (TLPD) was developed. characteristics TLPD in terms tuning conditions transfer functions were investigated series shaking table tests. Nonlinear behaviors frequency domain discussed, preliminary framework...
Automatic inspection of concrete surface defects based on visual elements is crucial for the timely detection security risks in infrastructure. Moreover, accurate determination geographical location detected critical subsequent maintenance and reinforcement tasks. This study employed convolutional neural network (CNN) training methods localization. approach employs bounding boxes to confine damaged pixels utilizes projection loss foster similarity learning between pixels. In addition,...
In this paper, a family of new step-up series-parallel dual resonant switched-capacitor converters (SP-DRSCs) is proposed to extend the conversion ratio for high applications. The feature wide gain range, continuously adjustable, and enhanced light-load voltage regulation. All flying capacitors operate in resonance, eliminating transient current spikes charge sharing losses. Thus, zero-current-switching (ZCS) turn-on all transistors ZCS turn-off diodes are achieved. A comprehensive analysis...
In this article, a step-down switched-capacitor converter (SCC) and step-up SCC with an integrated passive regenerative snubber (PRS) are proposed based on the Cuk dual resonance core (DRC). The members of DRC family overcome barrier for SCCs to achieve continuous output voltage regulation. One remaining challenge is turn-off spikes oscillations during switch transient that cause stress power loss transistor diode. PRS eliminates across diode process. Moreover, zero switching (ZVS) turn-on...
Astronauts are under high stress for a long time because of the microgravity condition, which leads to anxiety, affects their learning and memory abilities, seriously impairs health astronauts. Aromatherapy can improve physical mental astronauts in way that moisturizes them softly silently. However, strong volatility fragrances inconvenience aroma treatment greatly limit application field spaceflight. In this study, reactive mesoporous silica nanoparticles were prepared encapsulate slowly...