Rhys Williams

ORCID: 0000-0002-5327-406X
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About
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Research Areas
  • Iron Metabolism and Disorders
  • Chronic Lymphocytic Leukemia Research
  • Erythropoietin and Anemia Treatment
  • Lymphoma Diagnosis and Treatment
  • Medical research and treatments
  • Research on Leishmaniasis Studies
  • Chronic Myeloid Leukemia Treatments
  • Heart Failure Treatment and Management
  • Hemoglobinopathies and Related Disorders
  • Plant Virus Research Studies
  • Renal function and acid-base balance
  • Plant and Fungal Interactions Research
  • Diabetes Management and Research
  • Cutaneous lymphoproliferative disorders research
  • Ultrasound and Hyperthermia Applications
  • Trypanosoma species research and implications
  • Electrolyte and hormonal disorders
  • Medication Adherence and Compliance
  • Biotechnology and Related Fields
  • Obesity and Health Practices
  • Bacteriophages and microbial interactions
  • Diabetes and associated disorders
  • Diabetes Management and Education
  • Healthcare cost, quality, practices
  • Potassium and Related Disorders

Gloucestershire Hospitals NHS Foundation Trust
2024

Princess of Wales Hospital
2024

Cwm Taf University Health Board
2023

University of South Australia
2019

Swansea University
2008

Nuffield Health
2001-2002

University of Leeds
2002

Flinders University
1998

Biochemical Society
1986

The University of Adelaide
1984-1985

The nucleotide sequence of the 3389 residues RNA 1 (Mr 1.15 X 10(6) Q strain cucumber mosaic virus (CMV) was determined, completing primary structure CMV genome (8617 nucleotides). sequenced by dideoxy-chain-termination method using M13 clones carrying sequences as well synthetic oligonucleotide primers on a template. At 5' end there are 97 noncoding between cap and first AUG (98-100), which is start single long open-reading frame. This reading frame encodes translation product 991 amino...

10.1111/j.1432-1033.1985.tb09025.x article EN European Journal of Biochemistry 1985-07-01

The nucleotide sequence of the 3035 residues RNA 2 ( M r 1.03 × 10 6 ) Q strain cucumber mosaic virus (CMV) was determined by sequencing M13 clones 2cDNA and dideoxy using primers prepared either from or chemical synthesis. A single long open reading frame starts at second AUG 5′ end encodes 839 amino acids 94333). This has flanking regions 92 nucleotides terminus 423 nudeotides 3′ terminus. Computer analysis showed that CMV a significant homology with brome (BMV) alfalfa (AMV) also region...

10.1111/j.1432-1033.1984.tb08370.x article EN European Journal of Biochemistry 1984-09-01

SUMMARY Infants respond to antigen by making antibody that is generally of low affinity for antigen. Somatic hypermutation immunoglobulin genes, and selection cells expressing mutations with improved antigen, are the molecular cellular processes underlying maturation affinity. We have reported previously neonates infants up 2 months age, including individuals undergoing strong immunological challenge, show very few mutated VH6 sequences, mutation frequencies in little evidence selection. now...

10.1046/j.1365-2249.1998.00694.x article EN Clinical & Experimental Immunology 1998-10-01

The Northern Territory (NT) is characterised by major health inequalities. A high proportion of the population Indigenous, with poor socioeconomic conditions and a burden disease. small NT - 1% total Australian dispersed over one-sixth Australia's land mass. Given this very low density geographical isolation many communities, access to services often difficult. Medical workforce recruitment retention have been persistent problems. Prior 2011, residents who aspired study medicine had leave...

10.22605/rrh4671 article EN cc-by Rural and Remote Health 2019-05-27

10.1016/j.mpaic.2023.01.005 article EN Anaesthesia & intensive care medicine 2023-03-21
Robin Ray Ian Ford John G.F. Cleland Fraser J Graham Fozia Ahmed and 95 more Abdallah Al‐Mohammad Peter J. Cowburn Chris Critoph Philip A. Kalra Rebecca Lane Andrew Ludman Pierpaolo Pellicori Mark C. Petrie Michelle M. Robertson Alison Seed Iain Squire Paul R. Kalra Paul R. Kalra Elena Cowan Serena Howe Charlotte Turner Rosalynn Austin Rebeca Lane Paula Rogers Paul Foley Badri Chandrasekaran Eva Fraile Lynsey Kyeremeh Fozia Ahmed Mark Petrie Lorraine McGregor Joanna Osmanska Fraser J Graham Ninian N. Lang Bernhard Meyer Faheem Ahmad Joanna Osmanska Iain Squire Jude Fisher Philip A. Kalra Christina Summersgill Katarzyna Adeniji Rajkumar Chinnadurai Andrew Ludman Lisa Massimo Clare S. Hardman Daisy Sykes Peter J. Cowburn Sarah Frank Simon Smith Alan G. Japp Mohamed Anwar Beth Whittington Alison Seed Robin Ray Vennessa Sookhoo Abdallah Al‐Mohammad Janet Middle Kay Housley Andrew L. Clark Jeanne Bulemfu Christopher Critoph Victor Chong Stephen J. Wood Benjamin R. Szwejkowski Chim C. Lang Jackie Duff Susan M. MacDonald Rebekah Schiff John Donnelly Thuraia Nageh Swapna Kunhunny Mark Petrie Roy S. Gardner Marion McAdam Elizabeth McPherson Prithwish Banerjee Eleanor Sear Nigel Edwards Jason Glover Pierpaolo Pellicori Clare Murphy Justin Cooke Charles Spencer Mark L. Francis Iain Matthews Hayley McKie Andrew Marshall Janet Large Jenny Stratford Piers Clifford Sara Tavares Christopher J. Boos Philip J. Keeling Debbie Hughes Aaron Wong Deborah J. Jones Alex James Rhys Williams Stephen J Leslie

BackgroundIn some countries, intravenous (IV) ferric derisomaltose (FDI) is only licensed for treating iron deficiency with anemia. Accordingly, we investigated the effects of FDI in a subgroup patients anemia IRONMAN trial.Method and ResultsIRONMAN enrolled heart failure, left ventricular ejection fraction (LVEF) ≤45% (ferritin <100 µg/L or TSAT <20%), 771 (68%) whom had (hemoglobin <12 g/dL women; <13 men). Patients were randomized, open-label, to (n=397) usual care (n=374) followed median...

10.1016/j.cardfail.2023.10.006 article EN cc-by Journal of Cardiac Failure 2023-11-04

An abstract is not available for this content. As you have access to content, full HTML content provided on page. A PDF of also in through the ‘Save PDF’ action button.

10.1017/s0029665106005222 article EN Proceedings of The Nutrition Society 2006-11-01

e19049 Background: Acala and zanu are 2 nd generation Bruton tyrosine kinase inhibitors (BTKis) that have demonstrated improved safety profiles vs 1 st BTKi ibrutinib in clinical trials. While head-to-head comparison of acala is lacking, a recent meta-analysis trials provided comprehensive, indirect the AE B-cell malignancies (Hwang, Hemasphere. 2023;7(S3):1134). This study aims to evaluate costs impacts on quality life (QoL) for using their profiles. Methods: A health economic model was...

10.1200/jco.2024.42.16_suppl.e19049 article EN Journal of Clinical Oncology 2024-06-01

In this retrospective analysis, we evaluate the effectiveness of potassium (K+) binder sodium zirconium cyclosilicate (SZC) in maintaining normokalemia and facilitating initiation, optimization, maintenance renin–angiotensin–aldosterone system inhibitors (RAASi) patients with heart failure (HF) reduced ejection fraction (HFrEF). A total 44 HFrEF a history hyperkalemia who were receiving SZC to enable prescription RAASi identified from two district general hospital sites. Retrospective...

10.1007/s40119-024-00388-z article EN cc-by-nc Cardiology and Therapy 2024-11-01

10.17925/use.2006.00.1.16 article EN US Endocrinology 2006-01-01

<h3>Introduction</h3> Initiation &amp; optimisation of disease-modifying medicines in patients with heart failure a reduced ejection fraction (HFrEF) is the cornerstone management(1). Delivering optimal medical therapy (OMT)* has proven morbidity mortality benefits(1). The rising prevalence (HF) backlog pressure due impact COVID have put enormous on majority services country. There need to build capacity within HF meet demands. With appropriate training support, GP practice based, clinical...

10.1136/heartjnl-2023-bcs.82 article EN 2023-06-01
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