A5042560200- Polysaccharides Composition and Applications
- Drug Solubulity and Delivery Systems
- Food composition and properties
- Advanced Cellulose Research Studies
- Pharmaceutical studies and practices
- Advanced Drug Delivery Systems
- Polysaccharides and Plant Cell Walls
- Pharmaceutical Economics and Policy
- Analytical Methods in Pharmaceuticals
- Advancements in Transdermal Drug Delivery
- Ethnobotanical and Medicinal Plants Studies
- Microbial Metabolites in Food Biotechnology
- Nanoparticle-Based Drug Delivery
- Pharmacological Effects of Medicinal Plants
- Lignin and Wood Chemistry
- Pharmaceutical Quality and Counterfeiting
- Botanical Research and Chemistry
- Proteins in Food Systems
- Biotechnology and Related Fields
- Characterization and Applications of Magnetic Nanoparticles
- Pacific and Southeast Asian Studies
- Drug-Induced Hepatotoxicity and Protection
- Pharmacological Effects and Toxicity Studies
- Bee Products Chemical Analysis
- Cassava research and cyanide
Addis Ababa University
2014-2025
Martin Luther University Halle-Wittenberg
2012-2022
American Pharmacists Association
2016
University of Bahrain
2013-2015
There is no ethnobotanical study conducted specifically on medicinal plants traditionally used to treat cancer in Ethiopia. Yet, traditional herbalists different parts of the country claim that they have been treating cancer‐like symptoms using herbal remedies. The objective this was document eleven districts, Traditional were interviewed semistructured questionnaires, and field visits also carried out collect claimed for identification purpose. Seventy‐four herbalists, who knew about and/or...
Sterculia setigera gum, also known as gum karaya, is a vegetable produced an exudate. No teratogenic and mutagenic effects were reported from karaya toxicity studies. The aim of this study was to extract the fraction S. characterize its properties for potential application in pharmaceutical formulations. colour extracted powder grayish white, loss on drying 1.2 ± 0.7%, which showed suitability formulating stable tablets, especially moisture-sensitive drugs. total ash value 6.98 0.41%, within...
Background Medical devices (MDs) are critical components of healthcare systems, used for diagnosing and managing diseases. However, MDs have the potential adverse events hazards patients that could be assessed through post market surveillance (PMS). Objective This study was designed to assess PMS regulatory challenges, future perspectives in Ethiopia. Methods A mixed-methods conducted involving importers Addis Ababa Ethiopian Food Drug Authority (EFDA). Data were collected using checklists...
Ranitidine HCl, a selective, competitive histamine H 2 -receptor antagonist with short biological half-life, low bioavailability and narrow absorption window, is an ideal candidate for gastro-retentive drug delivery system (GRDDS). Controlled release optimum retentive formulation in the upper stomach would be this drug. The aim of present study was therefore to develop, formulate optimize floating, bioadhesive, swellable matrix tablets ranitidine HCl. were prepared using combination...
The present research work was aimed to formulate fast disintegrating tablets (FDTs) of salbutamol sulphate (SBS) using a combination superdisintegrant and subliming agent, optimize the formulation evaluate in vitro performance developed FDTs.A SBS FDT - crospovidone agent Ammonium Bicarbonate (AB) which variables, namely levels Microcrystalline Cellulose (MCC):Mannitol (MNTL) ratio, were evaluated for their effects on response disintegration time, hardness, friability wetting resulting FDTs....
Medicinal plants have been traditionally used to treat cancer in Ethiopia. However, very few studies reported the vitro anticancer activities of medicinal that are collected from different agro-ecological zones Hence, main aim this study was screen cytotoxic 80% methanol extracts 22 against human peripheral blood mononuclear cells (PBMCs), as well breast (MCF-7), lung (A427), bladder (RT-4), and cervical (SiSo) cell lines. Active were further screened large carcinoma (LCLC-103H), pancreatic...
Teff (Eragrostis tef), a grass which belongs to the Family Poaceae, is widely cultivated for its starch-rich grains in Ethiopia, generating large amounts of agricultural byproduct, teff straw. The aim this study was isolate and characterize cellulose microcrystalline (MCC) from straw evaluate MCC as directly compressible tablet excipient. Cellulose extracted partially depolymerized obtain MCC. physicochemical properties powders were characterized. Yields powder raw material 35.2% 27.2%,...
Olibanum is an oleo-gum resin which economically and culturally valuable product obtained from several species of the genus Boswellia. In this study, resins extracted local olibanum: Boswellia papyrifera (Tigray type) rivae (Ogaden were evaluated as matrix forming agents in sustained release tablet formulations employing diclofenac sodium a model drug. Some physico-chemical characterization revealed low solubility, moisture content swelling ratio. Sustained tablets containing 100 mg then...
The local gum of Acacia polyacantha was evaluated as a suspending agent in metronidazole benzoate suspensions comparison with senegal and NaCMC at concentration range 1-4% (w/v). resulting were for their sedimentation volume (%), degree flocculation, rheology, redispersibility, dissolution rate. Stability studies performed 3 months. apparent viscosities the order NaCMC>A. polyacantha>A. senegal. redispersibilities A. polyacanthaand comparable but better than those NaCMC. volumes (%) higher...
Background. Tablets are still the most preferred means of drug delivery. The search for new and improved direct compression tablet excipients is an area research focus. This because method overcomes drawbacks granulation methods production. It exempts several treatment steps associated with methods. requirements powders to be directly compressible include flowability, low friction tendency, compressibility, fast disintegration capacity. Taro Boloso-I a variety Colocasia esculenta (L. Schott)...