A5017943920- Spectroscopy Techniques in Biomedical and Chemical Research
- Spectroscopy and Chemometric Analyses
- Biosensors and Analytical Detection
- Extracellular vesicles in disease
- Epigenetics and DNA Methylation
- Meningioma and schwannoma management
- Digital Imaging for Blood Diseases
- Lysosomal Storage Disorders Research
- Brain Tumor Detection and Classification
- Infrared Thermography in Medicine
- MicroRNA in disease regulation
- Glioma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Lipid Membrane Structure and Behavior
Rzeszów University
2021-2025
Early detection of the most common pediatric neoplasm, B-cell precursor lymphoblastic leukemia (BCP-ALL), is challenging and requires invasive bone marrow biopsies. The purpose this study was to establish new biomarkers for early screening detect leukemia. In small cohort study, Fourier transform infrared (FTIR) spectra were obtained from blood sera 10 patients with BCP-ALL compared control samples children some conditions other than neoplasm. Using various analytical approaches, including a...
Medulloblastoma (MB) is the most common malignant tumor of central nervous system in childhood. FTIR spectroscopy provides a holistic view chemical composition biological samples, including detection molecules such as nucleic acids, proteins, and lipids. This study evaluated applicability potential diagnostic tool for MB.FTIR spectra MB samples from 40 children (boys/girls: 31/9; age: median 7.8 years, range 1.5-21.5 years) treated Oncology Department Children's Memorial Health Institute...
Background.Aberrant DNA methylation is an important mechanism by which the normal patterns of mi-croRNA expression are disrupted in human cancers including B-cell precursor acute lymphoblastic leukemia (BCP ALL), most common pediatric malignancy. Objectives.To characterize profile landscape microRNA genes BCP ALL patients. Materials and methods.We employed Infinium® MethylationEPIC BeadChip Arrays to measure from bone marrow samples children with (n = 38) controls without neoplasms...