A5005946751- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Retinopathy of Prematurity Studies
- Global Health and Surgery
- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Health Research
- Global Healthcare and Medical Tourism
- Neurological Disorders and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Global Health Workforce Issues
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Healthcare Quality and Management
- Syphilis Diagnosis and Treatment
- Cervical Cancer and HPV Research
- COVID-19 Pandemic Impacts
- Data-Driven Disease Surveillance
- Corneal Surgery and Treatments
- Child Abuse and Related Trauma
- Facial Trauma and Fracture Management
- Global Maternal and Child Health
London School of Hygiene & Tropical Medicine
2016-2025
University Hospitals Birmingham NHS Foundation Trust
2021-2025
University Medical Center Freiburg
2019-2025
Ophthalmology Clinic
2023-2025
University of Freiburg
2005-2024
National Eye Centre
2023
Centre for Sight
2023
Kilimanjaro Christian Medical Centre
2012-2022
London Vision Clinic
2022
University of London
2020
In sub-Saharan Africa, diabetes is a growing burden, yet little known about its prevalence, risk factors, and complications. To address these gaps help inform public health efforts aimed at prevention treatment, we conducted community-based study assessing epidemiology.
The conversion rate from untreated ocular hypertension (OHT) to glaucoma is only approximately 1% per year. Discrimination of nonconverters and potential converters would help reserve preventative treatment for those who need it thus avoid unnecessary side effects expenditure do not. This prospective study was designed assess the pattern electroretinogram (PERG) as an early indicator dysfunction preceding glaucoma.Ninety-five eyes 54 patients with intraocular pressure > or =25 mm Hg (or =23...
Background Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious cause of blindness worldwide. Yearly azithromycin mass drug administration (MDA) plays a central role in efforts to eliminate blinding trachoma as public health problem. Programmatic decision-making currently based on prevalence clinical sign "trachomatous inflammation-follicular" (TF) children. We sought test alternative tools for surveillance serology 12-year cohort Kahe Mpya, Rombo District, Tanzania,...
BackgroundGlaucoma is a major cause of sight loss worldwide, with the highest regional prevalence and incidence reported in Africa. The most common low-cost treatment used to control glaucoma long-term timolol eye drops. However, low adherence challenge. We aimed investigate whether selective laser trabeculoplasty (SLT) was superior drops for controlling intraocular pressure (IOP) patients open-angle glaucoma.MethodsWe did two-arm, parallel-group, single-masked randomised controlled trial at...
Introduction Globally, diabetic retinopathy (DR) is a major cause of blindness. Sub-Saharan Africa projected to see the largest proportionate increase in number people living with diabetes over next two decades. Screening for DR recommended prevent sight loss; however, many low and middle-income countries, because lack specialist eye care staff, current screening services are not optimal. The use artificial intelligence (AI) screening, which automates grading retinal photographs provides...
Ocular trauma in childhood is a major cause of unilateral acquired blindness Africa [3]. The aim the study was to identify underlying mechanisms injury order develop region-specific prevention strategies. performed at Department Ophthalmology Bugando Medical Centre Mwanza, Tanzania, during 3-month observation period spring 2019. All children under age 17 years who presented with acute eye or history ocular within 4 prior presentation were included. data collection using standardized...
Abstract Objective The number of adults with diabetes in sub‐Saharan Africa ( SSA ) is expected to almost double by 2035. This study investigated the prevalence diabetic retinopathy DR and its risk factors at entry into a community‐based screening programme. Methods All persons screened for programme Kilimanjaro Region, Tanzania between November 2010 December 2014 were included. Fundus photographs taken Topcon retinal camera following pupil dilation. Data collected on BP , random blood...
Diabetes is an emerging public health problem in sub-Saharan Africa. Diabetic retinopathy the commonest microvascular complication of diabetes and a leading cause blindness, mainly adults working age. Follow-up crucial to effective management diabetic retinopathy, however, follow-up rates are often poor The aim this study was assess proportion patients not presenting for reasons after screening Kilimanjaro Region Tanzania.All referred tertiary ophthalmology hospital 2012 were eligible...
Purpose: To compare severity of visual field (VF) loss at first presentation in glaucoma clinics England and Tanzania.Methods: Large archives VF records from automated perimetry were used to retrospectively examine vision Tanzania (N = 1,502) 9,264). Mean deviation (MD) the worse eye hospital visit was as an estimate detectable severity.Results: In Tanzania, 44.7% {CI95%: 42.2, 47.2} patients presented with severe (< −20 dB), versus 4.6% {4.1, 5.0} England. If we consider late also include...
Background . The Arclight ophthalmoscope is a low-cost alternative to standard direct ophthalmoscopes. This study compared the with Heine K180 evaluate its reliability in assessing vertical cup disc ratio (VCDR) and ease of use (EOU). Methods Eight medical students used both ophthalmoscopes examine optic 9 subjects. An EOU score was provided after every examination (a higher indicating that easier use). A consultant ophthalmologist reference VCDR. Results 288 examinations were performed....
Purpose: The purpose is to describe the outcome of trabeculectomy with transscleral cyclophotocoagulation (TSCPC) as an initial intervention for secondary childhood glaucoma in Northern Tanzania. Methods: A retrospective, consecutive case series was analyzed all children who underwent or TSCPC between 2000 and 2013 at a referral eye unit Retrospective data were collected on causes glaucoma, intraocular pressure (IOP), visual acuity, complications, subsequent interventions. Outcomes evaluated...
The XEN® gel stent reduces intraocular pressure (IOP) in glaucoma. XEN®-45 is widely used; the newer XEN®-63 has a larger lumen targeting potentially lower IOP outcomes. We retrospectively compared first 15 cases to matched controls. With preoperative of 18.1 ± 3.9 mmHg (mean SD) and final 9.1 2.0 mmHg, implantation resulted an reduction 44.6 16.5%. Similarly, with 18.3 4.5 10.3 2.1 40.1 17.2%. median follow-up period was 204 days (range 78-338 days) for group 386 99-1688 group. In total,...
Abstract Purpose To evaluate the efficacy of XEN ® -45 gel stent ab interno implantation for medically uncontrolled uveitic glaucoma. Methods Retrospective analysis 25 eyes receiving glaucoma from February 2019 to 2023 with recording intraocular pressure (IOP) values, ocular hypotensive medication, requirement revision or secondary surgery and complications. Prerequisites were a clear cornea, an open iridocorneal angle unscarred, mobile conjunctiva at site. Minimum follow-up required...
To investigate the barriers to access eye health services for patients with glaucoma in Tanzania aim of identifying key areas improvement and further research.Qualitative investigation using face-to-face semi-structured interviews recruited from Kilimanjaro Christian Medical Centre (KCMC) outpatient clinic. This project is part international strategy Research into Glaucoma Ethnicity (ReGAE) programme.Interviews were conducted help a translator; all data transcribed Swahili then translated...
Background/Aim Glaucoma accounts for 8% of global blindness and surgery remains an important treatment. We aimed to determine the impact adding simulation-based surgical education glaucoma. Methods designed a randomised controlled, parallel-group trial. Those assessing outcomes were masked group assignment. Fifty-one trainee ophthalmologists from six university training institutions in sub-Saharan Africa enrolled by inclusion criteria having performed no trabeculectomies randomised. control...
Die globale Ophthalmologie hat zum Ziel, das Sehvermögen, die Augengesundheit und Funktionsfähigkeit weltweit zu maximieren. Sie trägt so zur allgemeinen Gesundheit, Wohlbefinden, sozialen Teilhabe Lebensqualität eines jeden Einzelnen bei. Derzeit leben geschätzte 1,1 Mrd. Menschen mit einer Sehbehinderung, welche in 90 % der Fälle durch größtenteils kosteneffiziente Maßnahmen präveniert oder kuriert werden kann. Gleichzeitig betroffenen Regionen unzureichenden augenmedizinischen Versorgung....
Introduction: Glaucoma in Sub Saharan Africa (SSA) poses a daunting challenge. Communities are often unaware of the serious implications glaucoma and faced with limited access to specialists, making early detection management difficult. For those who have been diagnosed, socioeconomic barriers limit treatment.Since 2006, we involved an innovative program term 'STOP SSA'. The four main pillars this include building capacity, enhancing awareness, improving management. aim initiative is train...
<h3>Aim</h3> To evaluate goniotomy, trabeculotomy, transscleral cyclophotocoagulation (TSCPC) and trabeculectomy as initial procedures in children with primary childhood glaucoma from Northern Tanzania. <h3>Methods</h3> A retrospective analysis of consecutive interventions for 2000 to 2013 was conducted at the Kilimanjaro Christian Medical Centre. Success defined postoperative intraocular pressure (IOP) below 22 mmHg. rates, IOP, visual acuity (VA), subsequent potential risk factors failure...
By 2030, sub‐Saharan Africa is forecast to see the steepest rise in number of people with hypertension any world region. Hypertensive retinopathy known be a common complication developed countries and some studies suggest it associated presence other hypertension‐related end‐organ damage ( EOD ) such as stroke cardiovascular disease. In Tanzania relatively more than parts , especially older population; however, prevalence hypertensive its association remain unknown. The authors conducted...