A5037471075- Visual perception and processing mechanisms
- Ophthalmology and Visual Impairment Studies
- Neural dynamics and brain function
- Retinal Development and Disorders
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Health and Medical Studies
- Health Systems, Economic Evaluations, Quality of Life
- Retinal and Optic Conditions
- Tactile and Sensory Interactions
- Chronic Disease Management Strategies
- Multiple Sclerosis Research Studies
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Mental Health Treatment and Access
- Glaucoma and retinal disorders
- Multisensory perception and integration
- Neuroscience and Neural Engineering
- Hip and Femur Fractures
- Spatial Neglect and Hemispheric Dysfunction
- Psychiatric care and mental health services
- Advanced Vision and Imaging
- Face Recognition and Perception
- Social and Demographic Issues in Germany
- European and International Contract Law
University Medical Center Freiburg
2016-2025
University of Freiburg
2016-2025
Ophthalmology Clinic
2015-2024
Heinrich Heine University Düsseldorf
2023-2024
Heidelberg University
2023-2024
University Hospital Heidelberg
2023-2024
National Center for Tumor Diseases
2023-2024
University of Bern
2023-2024
Eye Center
2020-2024
University Hospital of Bern
2023
Leicht H, Heinrich S, Heider D, Bachmann C, Bickel van den Bussche Fuchs A, Luppa M, Maier W, Mösch E, Pentzek Rieder-Heller SG, Tebarth F, Werle J, Weyerer Wiese B, Zimmermann T, König H-H, for the AgeCoDe study group. Net costs of dementia by disease stage. Objective: To estimate net degree severity from a societal perspective, including detailed assessment formal and informal nursing care. Method: In cross-sectional study, illness were analysed in 176 patients 173 matched non-demented...
The EQ-5D is a generic questionnaire which generates health profile as well index scores for health-related quality of life that may be used in cost-utility analysis. To examine validity and responsiveness the patients with anxiety disorders. 389 disorders completed at baseline 6-month follow-up. Subjective measures (WHOQOL-BREF) psychopathology (BAI, BDI-II, BSQ, ACQ, MI) were comparison. Validity was analyzed by assessing associations between related other scores. Responsiveness...
The International Society for Clinical Electrophysiology of Vision (ISCEV) standard visual evoked potentials (VEPs) describes a minimum procedure clinical VEP testing and encourages more extensive testing. This ISCEV extended protocol is an extension to the standard. It procedures recording multiple VEPs range sizes pattern stimuli establish spatial frequency limit (threshold) relating this acuity.
Abstract The electroretinogram (ERG), a non-invasive electrophysiological tool used in ophthalmology, is increasingly applied to investigate neural correlates of depression. present study aimed reconsider previous findings major depressive disorder (MDD) reporting (1) diminished contrast sensitivity and (2) reduced patten ERG (PERG) amplitude ratio, additionally, assess (3) the photopic negative response (PhNR) from flash (fERG), with RETeval® device, more practical option for clinical...
Optic neuritis leads to degeneration of retinal ganglion cells whose axons form the optic nerve. The standard treatment is a methylprednisolone pulse therapy. This slightly shortens time recovery but does not prevent neurodegeneration and persistent visual impairment. In phase II trial performed in preparation this study, we have shown that erythropoietin protects global nerve fibre layer thickness (RNFLT-G) acute neuritis; however, preparatory was powered show effects on function. Treatment...
Optical blur from defocus is quite frequently considered as equivalent to low-pass filtering. Yet that belief, although not entirely wrong, inaccurate. Here, we wish disentangle the concepts of dioptric blur, caused by myopia or mis-accommodation, due filtering when convolving with a Gaussian kernel. Perhaps surprisingly-if well known in optometry-the representation kernel (or point-spread function) for is, good approximation and disregarding diffraction, simply cylinder. Its projection onto...
Transcranial direct current stimulation (tDCS) is increasingly used as a form of noninvasive brain to treat psychiatric disorders; however, its mechanism action remains unclear. Prolonged visual (PVS) can enhance evoked EEG potentials (visually potentials, VEPs) and has been proposed tool examine long-term potentiation (LTP) in humans. The objective the study was induce analyze VEP plasticity whether tDCS could either modulate or mimic changes induced by PVS. Thirty-eight healthy...
Abstract Background Optical coherence tomography (OCT) has emerged as a significant non-invasive imaging technique in psychiatric research, allowing for detailed structural assessment of the retinal layers. While OCT been promising monitoring neurodegeneration Alzheimer’s and Parkinson’s diseases, results major depressive disorder (MDD) remain inconsistent. Building on findings attenuated electroretinogram (ERG) responses MDD, indicating functional alterations, this study investigated...
Background Hip fractures are a major public health burden. In industrialized countries about 20% of all femoral occur in care dependent persons living nursing and assisted facilities. Preventive strategies for these groups needed as the access to medical services differs from independent home dwelling older at risk osteoporotic fractures. It was objective study evaluate effect fall fracture prevention program on incidence homes Bavaria, Germany. Methods translational intervention introduced...
Abstract The electroretinogram (ERG) allows the investigation of retinal signaling pathways and has increasingly been applied in individuals with mental disorders search for potential biomarkers neurodevelopmental disorders. Preceding ERG examinations autism spectrum (ASD) showed inconsistent results, which might be due to small number participants, heterogeneity ASD population, differences age ranges, stimulation methods. aim this study was investigate functional responses adults by means...
Abstract Ophthalmological methods have increasingly raised the interest of neuropsychiatric specialists. While integrity retinal cell functions can be evaluated with electroretinogram (ERG), optical coherence tomography (OCT) allows a structural investigation layer thicknesses. Previous studies indicate possible functional and alterations in patients schizophrenia. Twenty-five paranoid schizophrenia 25 healthy controls (HC) matched for age, sex, smoking status participated this study. Both,...
Erythropoietin (EPO) is a candidate neuroprotective drug. We assessed its long-term safety and efficacy as an adjunct to methylprednisolone in patients with optic neuritis focused on conversions multiple sclerosis (MS).The TONE trial randomized 108 acute but without previously known MS either 33,000 IU EPO or placebo conjunction 1,000 mg daily for 3 days. After reaching the primary end point at 6 months, we conducted open-label follow-up 2 years after randomization.The was attended by 83 of...