A5004316535- Dementia and Cognitive Impairment Research
- Chronic Disease Management Strategies
- Health Systems, Economic Evaluations, Quality of Life
- Prostate Cancer Diagnosis and Treatment
- Geriatric Care and Nursing Homes
- Health disparities and outcomes
- Health and Medical Studies
- Psychiatric care and mental health services
- Frailty in Older Adults
- Total Knee Arthroplasty Outcomes
- Global Health Care Issues
- Spatial Neglect and Hemispheric Dysfunction
- Clinical practice guidelines implementation
- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Bladder and Urothelial Cancer Treatments
- Obstructive Sleep Apnea Research
- Blood transfusion and management
- Urinary Bladder and Prostate Research
- Health, psychology, and well-being
- Renal cell carcinoma treatment
- Pelvic floor disorders treatments
- Intergenerational Family Dynamics and Caregiving
- Social and Demographic Issues in Germany
- Neurological Disorders and Treatments
Wissenschaftliches Institut der AOK
2015-2025
Helios Kliniken
2021
University Medical Center Hamburg-Eppendorf
2011-2013
Universität Hamburg
2011-2013
Institute of Health Economics
2012
Leipzig University
2008-2010
University Hospital Leipzig
2009
Icahn School of Medicine at Mount Sinai
2008
Background Multimorbidity has a negative impact on health-related quality of life (HRQL). Previous studies included only limited number conditions. In this study, we analyse the large conditions HRQL in multimorbid patients without preselecting particular diseases. We also explore effects these specific dimensions HRQL. Materials and Methods This analysis is based multicenter, prospective cohort study 3189 primary care aged 65 to 85. The 45 was analysed. severity rated. EQ-5D, consisting 5...
Leicht H, Heinrich S, Heider D, Bachmann C, Bickel van den Bussche Fuchs A, Luppa M, Maier W, Mösch E, Pentzek Rieder-Heller SG, Tebarth F, Werle J, Weyerer Wiese B, Zimmermann T, König H-H, for the AgeCoDe study group. Net costs of dementia by disease stage. Objective: To estimate net degree severity from a societal perspective, including detailed assessment formal and informal nursing care. Method: In cross-sectional study, illness were analysed in 176 patients 173 matched non-demented...
Background Whether late-onset depression is a risk factor for or prodrome of dementia remains unclear. We investigated the impact depressive symptoms and early- v . on subsequent in cohort elderly general-practitioner patients ( n = 2663, mean age 81.2 years). Method Risk was estimated over three follow-ups (each 18 months apart) depending history depression, particularly onset, current using proportional hazard models. also examined additive prediction incident by beyond cognitive...
Abstract Impaired insight for deficits (anosognosia) is common in Alzheimer’s disease (AD). However, it has not yet been determined clearly (a) whether different methods assessing are comparable, and (b) anosognosia affects domains to degrees (domain-specificity). was investigated 32 patients with AD, who were each accompanied by a caregiver. Anosognosia assessed global clinical rating, questionnaire discrepancies (patient vs. caregiver) covering domains, performance (self-assessment...
Stein J, Luppa M, Maier W, Wagner Wolfsgruber S, Scherer Köhler Eisele Weyerer Werle Bickel H, Mösch E, Wiese B, Prokein Pentzek Fuchs A, Leicht König H‐H, Riedel‐Heller SG for the AgeCoDe Study Group. Assessing cognitive changes in elderly: Reliable Change Indices Mini‐Mental State Examination. Objective: The diagnosis of dementia includes evidence decline functioning over time measured by objective tasks. Normative data adjusted impact socio‐demographic factors on test performance are...
Abstract Background Volume–outcome relationships related to major surgery may be of limited value if observation ends at the point discharge without taking transfers and later events into consideration. Methods The volume–outcome relationship in patients who underwent pancreatic between 2008 2010 was assessed using claims data for all inpatient episodes from Germany's largest provider statutory health insurance covering about 30 per cent population. Multiple logistic regression models with...
Objective To analyse predictors of costs in dementia from a societal perspective longitudinal setting. Method Healthcare resource use and were assessed retrospectively using questionnaire four waves at 6-month intervals sample patients (N = 175). Sociodemographic data, severity comorbidity baseline, cognitive impairment basic instrumental activities daily living also recorded. Linear mixed regression models with random intercepts for individuals used to total sector-specific costs. Results...
Zusammenfassung Aufgrund des demografischen Wandels und damit verbundener erwarteter Steigerungen der Fallzahlen von primärer Hüftendoprothetik Revisionseingriffen ist es wichtig, Faktoren zu identifizieren, die Komplikationen Revisionen reduzieren können. Ein solcher Faktor Fallzahl eines Krankenhauses. Studien haben gezeigt, dass Krankenhäuser mit höheren niedrigere Morbiditäts- Komplikationsraten aufweisen. Die meisten basieren dabei auf Registerdaten, oft unvollständig sind keine...
Social support has been suggested to positively influence cognition and mortality in old age. However, this suggestion questioned due inconsistent operationalisations of social among studies the small number longitudinal available. This study aims investigate perceived support, understood as emotional component on age part a prospective multicentre Germany. A national subsample 2,367 primary care patients was assessed twice over an observation period 18 months regarding cognitive function...
To analyze the impact of multimorbidity (MM) on health care costs taking into account data heterogeneity.Data come from a multicenter prospective cohort study 1,050 randomly selected primary patients aged 65 to 85 years suffering MM in Germany. was defined as co-occurrence ≥3 conditions list 29 chronic diseases. A conditional inference tree (CTREE) algorithm used detect underlying structure and most influential variables inpatient care, outpatient medications well formal informal nursing...
The present study investigates the effect of anosognosia (impaired insight for an illness) and cognitive deficits on reliability validity self-rated Quality Life (QoL) in Mild Cognitive Impairment (MCI) Alzheimer's Disease (AD). Cross-sectional study. with a consecutive clinical sample from memory clinic Leipzig (Germany). 27 patients (aged 65 years or above) diagnosis either MCI (N=12) AD (N=15), each together caregiver. patients' QoL was measured using Dementia self proxy ratings (DEMQoL...
Background/Aims: In the past few decades, a number of studies investigated risk factors nursing home placement (NHP) in dementia patients. The aim study was to investigate NHP incident cases, considering characteristics at time diagnosis. Methods: 254 cases from German general practice sample aged 75 years and older which were assessed every 1.5 over 4 waves included. A Cox proportional hazard regression model used determine predictors NHP. Kaplan-Meier survival curves evaluate until...
ABSTRACT Background: Depression in old age is common. Only few studies examined the association of depressive symptoms and direct costs elderly a cross-sectional way. This study aims to investigate prospectively health service use over course 4.5 years considering also different courses symptomatology. Methods: 305 primary care patients aged 75+ were assessed face-to-face regarding (Geriatric Scale), at baseline later. Resource utilization was monetarily valued using 2004/2005 prices. The...
No large-scale comparison of the 4 most established surgical approaches for lower urinary tract symptoms due to benign prostate obstruction in terms long-term efficacy is available. We compared photoselective vaporization, laser enucleation and open simple prostatectomy transurethral resection with regard 5-year reintervention rates.A total 43,041 male patients who underwent (34,526), vaporization (3,050), (1,814) or (3,651) between 2011 2013 were identified pseudonymized claims core data...
<i>Background:</i> Maintaining independence in instrumental activities of daily living (IADL) is crucial for older adults. This study explored the association between cognitive and functional performance general single IADL domains. Also, risk factors developing impairment were assessed. <i>Methods:</i> Here, 3,215 patients aged 75–98 years included. Data collected during home visits. <i>Results:</i> Cognitive functioning was associated with both...