A5078567094- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Thermography and Photoacoustic Techniques
- Ultrasound and Hyperthermia Applications
- Thermoregulation and physiological responses
- Enzyme Catalysis and Immobilization
- Innovative Microfluidic and Catalytic Techniques Innovation
- Angiogenesis and VEGF in Cancer
- Mesoporous Materials and Catalysis
Pennsylvania State University
2023-2024
National Institute of Technology Warangal
2023
National Institute of Technology Andhra Pradesh
2021
Abstract Studying brain‐wide hemodynamic responses to different stimuli at high spatiotemporal resolutions can help gain new insights into the mechanisms of neuro‐ diseases and ‐disorders. Nonetheless, this task is challenging, primarily due complexity neurovascular coupling, which encompasses interdependent parameters including cerebral blood volume (CBV), flow (CBF), oxygen saturation (SO 2 ). The current brain imaging technologies exhibit inherent limitations in resolution, sensitivity,...
Photoacoustic (PA) imaging provides deep tissue molecular of chromophores with optical absorption contrast and ultrasonic resolution. Present PA techniques are predominantly limited to one 2-D plane per acquisition. The ultrasound (US) transducers, required for real-time 3-D imaging, high cost, complex fabricate, have scalability in design. We present novel printed circuit board (PCB)-based matrix US transducer arrays that capable being bulk manufactured at low cost without using laborious...
Abstract Vascular diseases are a leading cause of death and disability worldwide. Despite having precursor conditions like peripheral arterial disease (PAD), they often only diagnosed after the onset stroke or heart attack. Low‐cost, portable, noninvasive, point‐of‐care (POC), label‐free assessment deep vascular function benefits PAD diagnosis, especially in resource poor settings world. Doppler ultrasound‐based blood flow measurements can diagnose PAD, albeit with limited sensitivity...
Noninvasive mapping of chromophore distribution in deep tissue is highly desired numerous biomedical applications. Multispectral photoacoustic (PA) imaging fused with linear spectral unmixing employed to generate 2-D and 3-D maps chromophores. However, wavelength depth dependent attenuation optical fluence leads nonuniform variations the behavior biomolecules affecting accuracy conventional methods. To address this, a modified independent component analysis (ICA) model proposed construct...
Abstract Over the past decades, there has been an escalating rise in need for chemicals and catalytic materials to keep up with global demands. Addressing those issues by conventional methods often becomes inefficient, myriad operational risks. Process intensification through procedural equipment‐based modifications have considered greener, higher heat mass transfer rates, operate lower costs. In this review, research using ultrasonic reactors microreactors, along developments integrated...
Vascular diseases are a leading cause of death and disability worldwide. Despite having precursor conditions like peripheral arterial disease (PAD), they often only diagnosed after the onset strokes or heart attacks. Low-cost, portable, non-invasive, point-of-care (POC) assessment deep vascular function benefits PAD diagnosis, especially in low-and-middle-income countries. Doppler ultrasound-based blood flow measurements can diagnose PAD, albeit, with limited sensitivity specificity. To...
2-D Ultrasound (US) Transducer (2D-UST) arrays facilitate scan-less volumetric photoacoustic imaging (3D-PAI), but are typically high-cost, involve laborious fabrication process, and permit limited scalability in design with respect to array parameters like element count, aperture size, center frequency ( 𝑓<i><sub>c</sub></i>) pitch. In this work, we report a novel, matrix UST fabricated on printed circuit board (PCB) substrate (2D-PCB-UST array) at low-cost without the need of advanced...
Understanding brain-wide hemodynamic responses to different stimuli at high spatiotemporal resolutions can help study neuro-disorders and brain functions. However, the existing imaging technologies have limited resolution, sensitivity, depth provide information about only one or two parameters. To address this, we propose a multimodal functional ultrasound photoacoustic (fUSPA) platform, which integrates ultrafast multispectral methods in compact head-mountable device, quantitatively map...