A5065929066- Photoacoustic and Ultrasonic Imaging
- Ultrasound Imaging and Elastography
- Optical Imaging and Spectroscopy Techniques
- Thermography and Photoacoustic Techniques
- Ultrasound and Hyperthermia Applications
- Disaster Response and Management
- Nanoplatforms for cancer theranostics
- Viral Infections and Outbreaks Research
- Urinary and Genital Oncology Studies
- Rheumatoid Arthritis Research and Therapies
- Poisoning and overdose treatments
- Ultrasonics and Acoustic Wave Propagation
- Quality and Safety in Healthcare
- RNA Interference and Gene Delivery
- Drug-Induced Hepatotoxicity and Protection
- Advanced biosensing and bioanalysis techniques
- Pain Mechanisms and Treatments
- Bladder and Urothelial Cancer Treatments
- Functional Brain Connectivity Studies
- Healthcare Technology and Patient Monitoring
- Concrete Properties and Behavior
- Bone health and treatments
- Ion Channels and Receptors
- Evaluation of Teaching Practices
- CRISPR and Genetic Engineering
Pennsylvania State University
2019-2025
Taiyuan University of Technology
2025
Dongguan University of Technology
2025
Huazhong University of Science and Technology
2023-2024
Shanghai Jiao Tong University
2024
Shanghai Children's Medical Center
2022-2024
Hebei Medical University
2023-2024
First Affiliated Hospital of Zhengzhou University
2024
East China Normal University
2024
South China University of Technology
2023
The fructus of Kadsura coccinea known as 'Bu-Fu-Na' is an emerging internet-famous fruit. For deep processing related products, approach combining LC-MS analysis, network pharmacological prediction, and experimental validation was adopted to explore phytochemicals biological functions K. pericarpium (KCP) for the first time. In total, 9 lignans 11 triterpenoids in KCP chloroform extract were identified by HPLC-Q-TOF/MS, these chemicals acted on their key targets through multiple signaling...
A Chinese medical team managed Ebola virus disease (EVD) patients in Sierra Leone from October 2014 to March 2015 and attended 693 suspected patients, of whom 288 had confirmed disease.A retrospective study was conducted the with disease. Clinical symptoms, manifestations, serum viral load were analyzed compared among different groups for mortality survival time.Among EVD (149 male 139 female, median age 28 years, log 6.68), 98 died, 36 recovered, 154 lost follow-up. Common symptoms fever...
Brain-inspired synaptic transistors have been considered as a promising device for next-generation electronics. To mimic the behavior of biological synapse, both data processing and nonvolatile memory capability are simultaneously required single electronic device. In this work, simple approach to realize transistor with improved characteristics is demonstrated by doping an ionic additive, tetrabutylammonium perchlorate (TBAP), into active polymer semiconductor without using any extra charge...
The opacity of conventional ultrasound transducers can impede the miniaturization and workflow current photoacoustic systems. In particular, optical-resolution microscopy (OR-PAM) requires coaxial alignment optical illumination acoustic-detection paths through complex beam combiners a thick coupling medium. To overcome these hurdles, we developed novel OR-PAM method on basis our recently reported transparent lithium niobate (LiNbO
Some major construction projects require materials that can quickly and easily obtain high mechanical properties. Nowadays sulfoaluminate cement (SAC) has attracted attention for such due to its fast hardening rate, early strength, low alkalinity. Added strength agents are commonly used improve the of Ultra-high performance concrete (UHPC). Most early-strength agent research focused on Portland systems. Due different components SAC cement, compatibility between needs be further explored.This...
Biodiesel has wide application prospects due to its good power performance, fuel economy and emission reduction. Experimental studies have found that the measured engine vibration presents an N-shaped nonlinear trend with increase of biodiesel proportion in blends, which cannot be explained solely based on combustion characteristics blended fuels. To study mechanisms for this vibration, a two-degree-of-freedom model piston–cylinder system was established verified analyse correspondence...
Ultrasound neuromodulation is a rapidly advancing, non-invasive technique with significant therapeutic potential for treating various neurological disorders. Although extensive in vitro and vivo studies have provided valuable insights into its modulatory effects, the underlying mechanisms remain poorly understood, limiting clinical translation. Optical neuroimaging techniques can help investigate these mechanisms; however, opacity bulkiness of conventional ultrasound transducers pose...
Gas pipeline leakage will result in casualties and property losses if not detected time. Conventional localization methods usually rely on dense grid distribution, leading to high computational costs. This study proposes a time-reversal-based adaptive generation approach enhance efficiency localization. The method introduces resolution adjustment parameter optimize captured signals, allowing for concentration areas based energy distribution. Based this principle, three steps—including signal...
We recently introduced piezoelectric lithium niobate (LN) based transparent ultrasound transducers (TUT) as a new platform for developing multimodal optical, and photoacoustic imaging systems. However, LN TUT is limited in its signal-to-noise ratio due to material's low piezoelectricity (d33). In this paper, we report, the first time, 0.2 mm thick lead magnesium niobate-lead titanate (PMN-PT) (PMN-PT-TUT) applications compared performance with 0.25 (LN-TUT). To improve energy transmission...
ABSTRACT Aims This research aimed to investigate the specific mechanism of methyltransferase like 3 (METTL3) in progression diabetic kidney disease (DKD). Materials and Methods The model was established with HK‐2 cells mice vitro vivo . N6 methyladenosine (m6A) contents tissues were detected a commercial kit m6A levels PTEN induced putative kinase 1 (PINK2) MeRIP kit. mRNA protein determined RT‐qPCR western blot. ROS, TNF‐α, IL‐6 assessed ELISA. cell proliferative ability measured by CCK‐8...
Optical resolution photoacoustic microscopy (OR-PAM) can map the cerebral vasculature at capillary-level resolution. However, OR-PAM setup's bulky imaging head makes awake mouse brain challenging and inhibits its integration with other optical neuroimaging modalities. Moreover, glass cranial windows used for are unsuitable due to acoustic impedance mismatch between plate tissue. To overcome these challenges, we propose a lithium niobate based transparent ultrasound transducer (TUT) as window...
Objective and Impact Statement. Simultaneous imaging of ultrasound optical contrasts can help map structural, functional, molecular biomarkers inside living subjects with high spatial resolution. There is a need to develop platform facilitate this multimodal capability improve diagnostic sensitivity specificity. Introduction . Currently, combining ultrasound, photoacoustic, modalities challenging because conventional transducer arrays are optically opaque. As result, complex geometries used...
Bio-based carbon capture and utilization emerges as a critical pathway to mitigate dioxide (CO2) emissions from industrial activities. Within this context, plant factories become an innovative solution for biological within parks, fed with the substantial inherent in exhaust gases maximize their sequestration capabilities. Among various species suitable such factories, Pennisetum giganteum becomes candidate best potential, characterized by its high photosynthetic efficiency (rapid growth...
Abstract Studying brain‐wide hemodynamic responses to different stimuli at high spatiotemporal resolutions can help gain new insights into the mechanisms of neuro‐ diseases and ‐disorders. Nonetheless, this task is challenging, primarily due complexity neurovascular coupling, which encompasses interdependent parameters including cerebral blood volume (CBV), flow (CBF), oxygen saturation (SO 2 ). The current brain imaging technologies exhibit inherent limitations in resolution, sensitivity,...
In photoacoustic imaging, accurate spectral unmixing is required for revealing functional and molecular information of the tissue using multispectral imaging data. A significant challenge in deep-tissue nonlinear dependence received signals on local optical fluence distribution. To overcome this, we have deployed an end-to-end unsupervised neural network based autoencoders. The proposed method employs physical properties as constraints to which effectively performs outputs individual...
Abstract Background Persistent pain is the most reported symptom in patients with rheumatoid arthritis (RA); however, effective and brief assessment tools are lacking. We validated Chinese version of Global Pain Scale (C-GPS) RA proposed a short C-GPS (s-C-GPS). Method The study was conducted using face-to-face questionnaire survey multicenter cross-sectional design from March to December 2019. Patients aged > 18 years who met diagnostic criteria were included. Based on classical test...
The Ebola virus causes an acute, serious illness which is often fatal if untreated. However, factors affecting the survival of disease remain unclear. Here, we investigated prognostic (EVD) through various statistical models.Sixty three laboratory-confirmed EVD patients with relatively complete clinical profiles were included in study. All recruited at Jui Government Hospital, Sierra Leone between October 1st, 2014 and January 18th, 2015. We first whether a single presentation would be...
Infant brain imaging is highly challenging but necessary for diagnosing various prevalent disorders including vascular malformations, encephalitis, and abusive head trauma. Conventional technologies such as MRI, CT, PET are not suitable repeated use on neonates due to the of ionizing radiation (CT PET), need patient transport, uncomfortable environment, high cost, bulky equipment. A wearable photoacoustic (PAI) hat can be an ideal candidate this application. However, its practical...
Transparent ultrasound transducer (TUT) technology allows easy co-alignment of optical and acoustic beams in the development compact photoacoustic imaging (PAI) devices with minimum coupling. However, TUTs suffer from narrow bandwidth low pulse-echo sensitivity due to lack suitable transparent matching backing layers. Here, we studied translucent glass beads (GB) epoxy as an layer for lithium niobate piezoelectric material-based (LN-TUTs). The properties various volume fractions GB layers...
The receive sensitivity of lead zirconate titanate (PZT) piezoelectric micromachined ultrasound transducers (PMUTs) was improved by applying a DC bias during operation. PMUT is governed the voltage coefficient, h31,f. With applied biases (up to 15 V) on 2 μm PbZr0.52Ti0.48O3 film, e31,f increased 1.6 times, permittivity decreased factor 0.6, and coefficient ~2.5 times. For released devices, 2.5 times photoacoustic signal 1.9 with V bias. B-mode imaging experiments showed that bias, received...
We report on the development of combined ultrasound and photoacoustic imaging system using Lead Zirconate Titanate (PZT) based flexible bulk transducer arrays. The was made with a new simple technique electronically interfaced research to obtain image custom targets. also for first time, A-line signal from array thereby laying foundation body conformal co-registered system.